A lifelong bleeding disorder associated with a deficiency of plasminogen activator inhibitor type 1

PLASMINOGEN ACTIVATOR INHIBITOR IN PLASMA: RISK FACTOR FOR RECURRENT MYOCARDIAL INFARCTION

1987 • 1,516 citations

A study of proteases and protease-inhibitor complexes in biological fluids

1978 • 810 citations

Deficient t-PA Release and Elevated PA Inhibitor Levels in Patients with Spontaneous or Recurrent Deep Venous Thrombosis

1987 • 373 citations

Detection and partial characterization of an inhibitor of plasminogen activator in human platelets.

1984 • 365 citations

Two different mechanisms in patients with venous thrombosis and defective fibrinolysis: low concentration of plasminogen activator or increased concentration of plasminogen activator inhibitor.

1985 • 341 citations

Significance of Cross-Linking of α2-Plasmin Inhibitor to Fibrin in Inhibition of Fibrinolysis and in Hemostasis

1982 • 287 citations

Bleeding diathesis due to decreased functional activity of type 1 plasminogen activator inhibitor.

1989 • 208 citations

Congenital Deficiency of α2-Plasmin Inhibitor Associated with Severe Hemorrhagic Tendency *

1979 • 201 citations

The role of the fibrinolytic system in deep vein thrombosis.

1985 • 201 citations

Plasminogen activator inhibitor 1: development of a radioimmunoassay and observations on its plasma concentration during venous occlusion and after platelet aggregation

1987 • 195 citations

Daytime Fluctuations in Blood of Tissue-Type Plasminogen Activator (t-PA) and Its Fast-Acting Inhibitor (PAI-1)

1988 • 183 citations

Studies on the Release of a Plasminogen Activator Inhibitor by Human Platelets

1986 • 152 citations

Measurement of human tissue-type plasminogen activator by a two-site immunoradiometric assay.

1983 • 142 citations

Diurnal Variation of the Fibrinolytic System

1988 • 138 citations

Identification of and partial characterization of platelet vitronectin: evidence for complex formation with platelet-derived plasminogen activator inhibitor-1

1989 • 114 citations

Interaction between plasminogen activator inhibitor type 1 (PAI-1) bound to fibrin and either tissue-type plasminogen activator (t-PA) or urokinase-type plasminogen activator (u-PA). Binding of t-PA/PAI-1 complexes to fibrin mediated by both the finger and the kringle-2 domain of t-PA.

1989 • 99 citations

α2-PLASMIN-INHIBITOR DEFICIENCY (MIYASATO DISEASE)

1978 • 88 citations

The Fast-Acting Inhibitor of Tissue-Type Plasminogen Activator in Plasma Is also the Primary Plasma Inhibitor of Urokinase

1986 • 80 citations

Residual plasminogen activator inhibitor activity after venous stasis as a criterion for hypofibrinolysis: a study in 83 patients with confirmed deep vein thrombosis

1988 • 64 citations

A new life-long hemorrhagic disorder due to excess plasminogen activator

1983 • 62 citations

Genetic Abnormalities of the Fibrinolytic System

1984 • 59 citations

Release of vascular plasminogen activator (v‐PA) after venous stasis: electrophoretic—zymographic analysis of free and complexed v‐PA

1985 • 56 citations

Preoperative Identification of Patients at High Risk of Deep Venous Thrombosis Despite Prophylaxis in Total Hip Replacement

1988 • 45 citations

Increased Fibrinolysis and Amyloidosis

1983 • 43 citations

Human Z α₁‐antitrypsin accumulates intracellularly and stimulates lysosomal activity when synthesised in the Xenopus oocyte

1985 • 25 citations