Structure and Function ofE. ColiPromoter DN

Compilation and analysis ofEscherichia colipromoter DNA sequences

1983 • 2,228 citations

Dependency on Medium and Temperature of Cell Size and Chemical Composition during Balanced Growth of Salmonella typhimurium

1958 • 1,471 citations

The locus of sequence-directed and protein-induced DNA bending

1984 • 1,453 citations

DNA bending at adenine · thymine tracts

1986 • 1,032 citations

Structure of the nucleosome core particle at 7 Å resolution

1984 • 1,028 citations

MECHANISM AND CONTROL OF TRANSCRIPTION INITIATION IN PROKARYOTES

1985 • 1,012 citations

The tac promoter: a functional hybrid derived from the trp and lac promoters.

1983 • 1,001 citations

Factor Stimulating Transcription by RNA Polymerase

1969 • 983 citations

Sequence periodicities in chicken nucleosome core DNA

1986 • 930 citations

E. coli RNA polymerase interacts homologously with two different promoters

1980 • 911 citations

Gene regulation by proteins acting nearby and at a distance

1986 • 886 citations

REGULATION OF THE SYNTHESIS OF RIBOSOMES AND RIBOSOMAL COMPONENTS

1984 • 847 citations

DNA bending and its relation to nucleosome positioning

1985 • 702 citations

Reversible bending and helix geometry in a B-DNA dodecamer: CGCGAATTBrCGCG.

1982 • 626 citations

PROTEIN-NUCLEIC ACID INTERACTIONS IN TRANSCRIPTION: A Molecular Analysis

1984 • 620 citations

The htpR gene product of E. coli is a sigma factor for heat-shock promoters

1984 • 593 citations

Mechanics of sequence-dependent stacking of bases in B-DNA

1982 • 571 citations

The Selectivity of Transcription

1974 • 539 citations

Base sequence and helix structure variation in B and A DNA

1983 • 522 citations

Role of amino acids in osmoregulation of non-halophilic bacteria

1975 • 509 citations

Escherichia colipromoter sequences predictin vitroRNA polymerase selectivity

1984 • 492 citations

Helical repeat of DNA in solution.

1979 • 481 citations

DNA structural variations in the E. coli tyrT promoter

1984 • 448 citations

Transcription of glnA in E. coli is stimulated by activator bound to sites far from the promoter

1986 • 444 citations

An operator at -280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repression.

1984 • 375 citations

Consensus sequence for Escherichia coli heat shock gene promoters.

1985 • 372 citations

POSITIVE CONTROL OF TRANSCRIPTION INITIATION IN BACTERIA

1984 • 369 citations

Helical periodicity of DNA determined by enzyme digestion

1980 • 347 citations

REGULATION OF NITROGEN FIXATION GENES

1986 • 345 citations

The general affinity of lac repressor for E. coli DNA: Implications for gene regulation in procaryotes and eucaryotes

1975 • 341 citations

Transcription of glnA by purified Escherichia coli components: core RNA polymerase and the products of glnF, glnG, and glnL.

1985 • 335 citations

Repressor structure and the mechanism of positive control

1983 • 324 citations

Rate-limiting steps in RNA chain initiation.

1980 • 308 citations

Promoters of Escherichia coli: a hierarchy of in vivo strength indicates alternate structures.

1986 • 305 citations

DNA determinants of rRNA synthesis in E. coli: Growth rate dependent regulation, feedback inhibition, upstream activation, antitermination

1986 • 300 citations

Upstream activator sequences are present in the promoters of nitrogen fixation genes

1986 • 293 citations

The interaction of RNA polymerase and lac repressor with the lac control region

1979 • 283 citations

BACTERIAL REGULATION: GLOBAL REGULATORY NETWORKS

1984 • 279 citations

A topological model for transcription based on unwinding angle analysis of E. coli RNA polymerase binary, initiation and ternary complexes

1982 • 264 citations

The nudeotide sequence of the cloned rpoD gene for the RNA polymerase sigma subunit from E. coil K12

1981 • 262 citations

Sequence dependence of the curvature of DNA: a test of the phasing hypothesis

1985 • 259 citations

Kinetics of open complex formation between Escherichia coli RNA polymerase and the lac UV5 promoter. Evidence for a sequential mechanism involving three steps

1985 • 259 citations

THE REGULATION OF TRANSCRIPTION INITIATION IN BACTERIA

1985 • 251 citations

Stabilities of nearest‐neighbor doublets in double‐helical DNA determined by fitting calculated melting profiles to observed profiles

1981 • 238 citations

Curved DN

1985 • 236 citations

Initiation of DNA‐Dependent RNA Synthesis and the Effect of Heparin on RNA Polymerase

1967 • 233 citations

A structural basis for S1 nuclease sensitivity of double-stranded DNA

1985 • 232 citations

Control of rRNA and tRNA syntheses in Escherichia coli by guanosine tetraphosphate

1982 • 231 citations

Mechanism of CRP-cAMP activation of lac operon transcription initiation activation of the P1 promoter

1984 • 228 citations

Conformational change in the DNA associated with an unusual promoter mutation in a tRNA operon of Salmonella

1984 • 225 citations

The nif promoters of Klebsiella pneumoniae have a characteristic primary structure

1983 • 223 citations

Sequence-dependent variation in the conformation of DNA

1981 • 220 citations

Homocopolymer sequences in the spacer of a sea urchin histone gene repeat are sensitive to S1 nuclease

1982 • 220 citations

Two RNA polymerase sigma factors from Bacillus subtilis discriminate between overlapping promoters for a developmentally regulated gene

1983 • 218 citations

Conformation of promoter DNA: Fine mapping of S1-hypersensitive sites

1983 • 216 citations

Cruciform formation in a negatively supercoiled DNA may be kinetically forbidden under physiological conditions

1983 • 212 citations

Mechanism of activation of transcription initiation from the λPRM promoter

1982 • 210 citations

Evidence for the existence of stable curvature of DNA in solution.

1984 • 210 citations

Promoter Sequence for Stringent Control of Bacterial Ribonucleic Acid Synthesis

1980 • 208 citations

Chromatin and core particles formed from the inner histones and synthetic polydeoxyribonucleotides of defined sequence

1979 • 208 citations

DNA conformation at the 5′ end of the chicken adult β-globin gene

1983 • 206 citations

A base-centred explanation of the B-to-A transition in DNA

1984 • 205 citations

Control of ribosome synthesis

1975 • 204 citations

Intermediates in transcription initiation from the E. coli lac UV5 promoter

1985 • 202 citations

Differential stringent control of the tandem E. coli ribosomal RNA promoters from the rrnA operon expressed in vivo in multicopy plasmids

1983 • 202 citations

Nucleotide sequence of the heat shock regulatory gene of E. coli suggests its protein product may be a transcription factor

1984 • 198 citations

A dimer of AraC protein contacts three adjacent major groove regions of the araI DNA site.

1985 • 197 citations

Defining a bacteriophage T4 late promoter: Absence of a “−35” region

1984 • 192 citations

The bending of DNA in nucleosomes and its wider implications

1987 • 189 citations

Promoters: Structure and function

1983 • 186 citations

Regulation of nitrogen fixation genes

1984 • 182 citations

Nucleosome cores reconstituted from poly (dA-dT) and the octamer of histones

1979 • 172 citations

Conserved features of coordinately regulatedE.colipromoters

1984 • 167 citations

Requirement for an upstream element for optimal transcription of a bacterial tRNA gene

1983 • 163 citations

Temperature dependence of the rate constants of the Escherichia coli RNA polymerase-λP promoter interaction

1985 • 162 citations

Unwinding of double-stranded DNA helix by dehydration.

1981 • 160 citations

Functional dissection of Escherichia coli promoters: information in the transcribed region is involved in late steps of the overall process.

1986 • 159 citations

Dependence of the Putrescine Content of Escherichia coli on the Osmotic Strength of the Medium

1972 • 156 citations

The molecular topography of rna polymerase-promoter interaction

1979 • 153 citations

Characterization in vitro of the effect of spacer length on the activity of Escherichia coli RNA polymerase at the TAC promoter.

1985 • 149 citations

Negative supercoiling induces spontaneous unwinding of a bacterial promoter.

1985 • 141 citations

Changes in the DNA structure of the lac UV5 promoter during formation of an open complex with Escherichia coli RNA polymerase

1985 • 125 citations

On the action of the cyclic AMP-cyclic AMP receptor protein complex at the Escherichia coli lactose and galactose promoter regions.

1984 • 124 citations

Rapid "footprinting" on supercoiled DNA.

1985 • 121 citations

Bacteriophage λ protein cII binds promoters on the opposite face of the DNA helix from RNA polymerase

1983 • 116 citations

Some physical properties of RNA polymerase.

1966 • 116 citations

Physicochemical studies on interactions between DNA and RNA polymerase. Unwinding of the DNA helix by Escherichia coli RNA polymerase

1977 • 115 citations

DNA gyrase and its complexes with DNA: direct observation by electron microscopy

1985 • 113 citations

Modulation of RNA polymerase specificity by ppGpp

1976 • 110 citations

Establishment of exponential growth after a nutritional shift-up in Escherichia coli B/r: accumulation of deoxyribonucleic acid, ribonucleic acid, and protein

1977 • 110 citations

Structural junctions in DNA: the influence of flanking sequence on nuclease digestion specificities

1985 • 110 citations

The nucleotide sequence of the nitrogen-regulation genentrAofKlebsiella pneumoniaeand comparison with conserved features in bacterial RNA polymerase sigma factors

1985 • 105 citations

Sequence specificity of curved DNA

1986 • 102 citations

Promoter selectivity of Escherichia coli RNA polymerase. Differential stringent control of the multiple promoters from ribosomal RNA and protein operons.

1984 • 101 citations

Stringent control of bacterial transcription

1985 • 99 citations

Supercoiling response of the lac ps promoter in vitro

1985 • 96 citations

RNA polymerase interactions with the upstream region of the E. coli tyrT promoter

1983 • 93 citations

Activation of Transcription at Specific Promoters by Glycerol

1974 • 93 citations

Identification of initiation sites for the in vitro transcription of rRNA operons rrnE and rrnA in E. coli

1979 • 91 citations

Genetically separable functional elements mediate the optimal expression and stringent regulation of a bacterial tRNA gene

1985 • 90 citations

Regulation of the kinetics of the interaction of Escherichia coli RNA polymerase with the .lambda.PR promoter by salt concentration

1985 • 88 citations

Two functional domains conserved in major and alternate bacterial sigma factors

1985 • 85 citations

The effect of a lambda repressor mutation on the activation of transcription initiation from the lambda PRM promoter

1983 • 83 citations

Functional interrelationship between two tandem E. coli ribosomal RNA promoters

1983 • 83 citations

DNA supercoiling affects in vitro transcription of two maize chloroplast genes differently.

1985 • 79 citations

In vitro comparison of initiation properties of bacteriophage lambda wild-type PR and x3 mutant promoters.

1980 • 78 citations

Promoter recognition by Escherichia coli RNA polymerase. Effects of substitutions in the spacer DNA separating the -10 and -35 regions.

1986 • 75 citations

Binding of Escherichia coli RNA polymerase holoenzyme to bacteriophage T7 DNA

1982 • 74 citations

A mutation affecting the σ subunit of RNA polymerase changes transcriptional specificity

1978 • 69 citations

A Bent Helix in Kinetoplast DNA

1983 • 68 citations

Topography of interaction of Escherichia coli RNA polymerase subunits with lac UV5 promoter

1981 • 68 citations

Binding of Escherichia coli RNA polymerase holoenzyme to bacteriophage T7 DNA

1982 • 68 citations

Specific inhibition of ribosomal RNA synthesis in vitro by guanosine 3′ diphosphate, 5′ diphosphate

1975 • 66 citations

Multiple procaryotic ribonucleic acid polymerase sigma factors.

1986 • 62 citations

Binding of Escherichia coli ribonucleic acid polymerase holoenzyme to a bacteriophage T7 promoter-containing fragment: evaluation of promoter binding constants as a function of solution conditions

1980 • 62 citations

Effect of supercoiling on the abortive initiation kinetics of the RNA-I promoter of ColE1 plasmid DNA.

1984 • 62 citations

High-resolution analysis of lac transcription complexes inside cells

1986 • 61 citations

Synthesis and activity of ribonucleic acid polymerase in Escherichia coli

1980 • 60 citations

A tRNATyr promoter with an altered in vitro response to ppGpp

1980 • 58 citations

Genetic studies on the β subunit of Escherichia coli RNA polymerase

1986 • 55 citations

Supercoiling response of a bacterial tRNA gene.

1985 • 55 citations

Conformational analysis of lac promoters using the nuclease activity of 1,10‐phenanthroline‐copper ion

1985 • 54 citations

Promoter mutations in the transfer RNA gene tyrT of Escherichia coli.

1979 • 54 citations

Aggregation equilibria of Escherichia coli RNA polymerase: evidence for anion-linked conformational transitions in the protomers of core and holoenzyme

1982 • 53 citations

A new experimental approach for studying the association between RNA polymerase and thetetpromoter of pBR322

1984 • 53 citations

3 Bacterial DNA-Dependent RNA Polymerases

1982 • 50 citations

Regulation of the expression of the tufB operon: DNA sequences directly involved in the stringent control.

1985 • 49 citations

Ion Effects on the Aggregation and DNA-binding Reactions of Escherichia coli RNA Polymerase

1983 • 49 citations

Deoxyribonuclease I produces staggered cuts in the DNA of chromatin

1977 • 46 citations

The pathway ofE. coliRNA polymerase-promoter complex formation as visualized by footprinting

1985 • 44 citations

Nucleotide sequence of the promoter region of the gene cluster for proton-translocating ATPase from Escherichiacoli and identification of the active promoter

1982 • 44 citations

Positive control of transcription initiation in Escherichia coli

1985 • 44 citations

rpoB mutation in Escherichia coli alters control of ribosome synthesis by guanosine tetraphosphate

1983 • 43 citations

Relaxed mutants of Escherichia coli RNA polymerase

1983 • 41 citations

Analysis of RNA polymerase by trypsin cleavage. Evidence for a specific association between subunits sigma and beta involved in the closed to open complex transition.

1980 • 41 citations

Mutations affecting regulation of the Klebsiella pneumoniae nifH (nitrogenase reductase) promotor

1984 • 41 citations

The structure of the nucleosome core particle

1986 • 40 citations

The selection and characterization of two novel mutations in the overlapping promoters of the Escherichia coli galactose operon

1984 • 38 citations

Alteration of the growth-rate-dependent regulation of Escherichia coli tyrT expression by promoter mutations

1986 • 38 citations

On the Nature of DNA Promoter Conformations

1974 • 38 citations

Binding of CRP to DNA-dependent RNA polymerase from E. coli: Modulation by cAMP of the interactions with free and DNA-bound holo and core enzyme

1980 • 37 citations

Differential effects of mutations on discrete steps in transcription initiation at the λ PRE promoter

1983 • 37 citations

In vitro transcription of three different ribosomal RNA cistrons of E. coli; heterogeneity of control regions

1977 • 36 citations

Promoter selectivity ofEscherichia coliRNA polymerase: alteration by fMet-tRNA_f^Met

1986 • 33 citations

Bent DNA for gene regulation and DNA packaging

1985 • 31 citations

Effect of superhellcity on the transcription from the tet promoter of pBR322. Abortive initiation and unwinding experiments

1984 • 30 citations

The .sigma. subunit of RNA polymerase contacts the leading ends of transcripts 9-13 bases long on the .lambda. PR promoter but not on T7 A1

1986 • 28 citations

Formylmethionyl-tRNA alters RNA polymerase specificity.

1980 • 27 citations

In vitro transcription initiation from three different Escherichia coli promoters

1985 • 27 citations

ppGpp regulates the binding of two RNA polymerase molecules to thetyrTpromoter

1982 • 26 citations

Equilibrium DNA-binding of AraC protein

1987 • 24 citations

The control of stable RNA synthesis in bacteria

1985 • 24 citations

Selective Inhibition of tRNA^Tyr Transcription by Guanosine 3′‐Diphosphate 5′‐Diphosphate

1977 • 22 citations

Small‐angle x‐ray study of DNA‐dependent RNA polymerase holoenzyme from Escherichia coli

1981 • 21 citations

The synthesis and cloning of two tyrosine suppressor tRNA genes with altered promoter sequences.

1981 • 19 citations

Functional heterogeneity of Escherichia coli ribonucleic acid polymerase holoenzyme

1980 • 17 citations

Selective inhibition of transcription of the E. coli tufB operon by guanosine-5′-diphosphate-3′-diphosphate

1983 • 16 citations

Effects of deletions near Escherichia coli rrnB promoter P2 on inhibition of in vitro transcription by guanosine tetraphosphate

1983 • 12 citations

An Escherichia coli RNA polymerase tight-binding site on T7 DNA is a weak promoter subject to substrate inhibition

1986 • 11 citations

Selectivity of RNA chain initiation in vitro. 3. Variables affecting initiation of transcription

1978 • 11 citations

DNA structure and promoter function

1986 • 8 citations

THE REGULATION OF RNA POLYMERASE BY GUANOSINE 5′-DIPHOSPHATE 3′-DIPHOSPHATE

1979 • 6 citations

Regulation of Gene Expression

2017 • 2 citations