Calcium modulates the generation of inositol 1,3,4-trisphosphate in human platelets by the activation of inositol 1,4,5-trisphosphate 3-kinase

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

1983 • 2,596 citations

Inositol phospholipids and cell surface receptor function

1975 • 2,458 citations

Platelet Sequestration in Man. I. Methods*

1964 • 830 citations

Micro-injection of inositol 1,3,4,5-tetrakisphosphate activates sea urchin eggs by a mechanism dependent on external Ca2+

1986 • 775 citations

Rapid formation of inositol 1,3,4,5-tetrakisphosphate following muscarinic receptor stimulation of rat cerebral cortical slices

1985 • 641 citations

The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane

1982 • 541 citations

Cytoplasmic free Ca²⁺ in human platelets: Ca²⁺ thresholds and Ca‐independent activation for shape‐change and secretion

1982 • 537 citations

The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics and unanswered questions

1981 • 518 citations

Metabolism of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in rat parotid glands

1985 • 450 citations

The rapid formation of inositol phosphates in human platelets by thrombin is inhibited by prostacyclin.

1984 • 319 citations

Agonists stimulate divalent cation channels in the plasma membrane of human platelets

1985 • 303 citations

Inositol trisphosphates in carbachol-stimulated rat parotid glands

1984 • 296 citations

Mass changes in myoinositol trisphosphate in human platelets stimulated by thrombin. Inhibitory effects of phorbol ester.

1985 • 292 citations

Liberation of [3H]arachidonic acid and changes in cytosolic free calcium in fura-2-loaded human platelets stimulated by ionomycin and collagen

1986 • 292 citations

Inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate formation in Ca2+-mobilizing-hormone-activated cells

1985 • 234 citations

Specificity of inositol phosphate-stimulated Ca2+ mobilization from Swiss-mouse 3T3 cells

1986 • 190 citations

Ca2+ regulates the inositol tris/tetrakisphosphate pathway in intact and broken preparations of insulin-secreting RINm5F cells.

1986 • 177 citations

Collagen stimulates [3H]inositol trisphosphate formation in indomethacin-treated human platelets

1985 • 122 citations

Synthesis and biological properties of a 9,11-azo-prostanoid: highly active biochemical mimic of prostaglandin endoperoxides.

1975 • 117 citations

Potentiation by thrombin of the secretion of serotonin from permeabilized platelets equilibrated with Ca2+ buffers. Relationship to protein phosphorylation and diacylglycerol formation

1984 • 110 citations

Inositol bis-, tris-, and tetrakis(phosphate)s: analysis in tissues by HPLC.

1986 • 93 citations

Regulation of inositol 1,4,5-trisphosphate kinase activity after stimulation of human T cell antigen receptor.

1987 • 77 citations

ADP stimulates IP₃ formation in human platelets

1986 • 75 citations

The role of cytosolic free calcium in the generation of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in HL-60 cells. Differential effects of chemotactic peptide receptor stimulation at distinct Ca2+ levels.

1986 • 71 citations

Calmodulin activates inositol 1,4,5-trisphosphate 3-kinase activity in pig aortic smooth muscle

1987 • 65 citations

Formation and metabolism of inositol 1,4,5-trisphosphate in human platelets

1987 • 52 citations

Interconversion of inositol (1,4,5)-trisphosphate to inositol (1,3,4,5)-tetrakisphosphate and (1,3,4)-trisphosphate in permeabilized adrenal glomerulosa cells is calcium-sensitive and ATP-dependent

1986 • 46 citations

Turnover of the phosphomonoester groups of polyphospoinositol lipids in unstimulated human platelets

1987 • 40 citations

Metabolism of inositol 1,4,5-trisphosphate in permeabilized rat aortic smooth-muscle cells. Dependence on calcium concentration

1987 • 31 citations

Determination of basal and stimulated levels of inositol triphosphate in [32P]orthophosphate-labeled platelets

1986 • 26 citations