Individual CD34+CD38lowCD19−CD10− Progenitor Cells From Human Cord Blood Generate B Lymphocytes and Granulocytes

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Isolation of a candidate human hematopoietic stem-cell population.

1992 • 1,098 citations

Developmental potential and dynamic behavior of hematopoietic stem cells

1986 • 888 citations

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

1994 • 807 citations

Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro

1989 • 699 citations

Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset

1995 • 687 citations

Long-term culture of B lymphocytes and their precursors from murine bone marrow.

1982 • 612 citations

The transcriptional control of hematopoiesis [see comments]

1996 • 608 citations

Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.

1992 • 536 citations

Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells

1996 • 495 citations

Functional Isolation and Characterization of Human Hematopoietic Stem Cells

1995 • 414 citations

Ontogeny-related changes in proliferative potential of human hematopoietic cells.

1993 • 413 citations

Bipotential precursors of B cells and macrophages in murine fetal liver

1992 • 367 citations

A stromal cell line from myeloid long-term bone marrow cultures can support myelopoiesis and B lymphopoiesis.

1987 • 345 citations

Lymphoid and myeloid differentiation of single human CD34+, HLA-DR+, CD38- hematopoietic stem cells

1994 • 314 citations

Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow

1990 • 308 citations

Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice

1994 • 283 citations

Cells and Molecules that Regulate B Lymphopoiesis in Bone Marrow

1989 • 272 citations

The expression of Vpre-B/λ5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice

1994 • 238 citations

The repopulation potential of fetal liver hematopoietic stem cells in mice exceeds that of their liver adult bone marrow counterparts

1996 • 236 citations

Phenotype and function of human hematopoietic cells engrafting immune- deficient CB17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells

1996 • 204 citations

Transduction of pluripotent human hematopoietic stem cells demonstrated by clonal analysis after engraftment in immune-deficient mice.

1996 • 186 citations

B cells are generated throughout life in humans.

1996 • 178 citations

Clonal proliferation of murine lymphohemopoietic progenitors in culture.

1992 • 163 citations

Estrogen suppresses stromal cell-dependent lymphopoiesis in culture.

1995 • 151 citations

Characterization and purification of a primitive hematopoietic cell type in adult mouse marrow capable of lymphomyeloid differentiation in long-term marrow "switch" cultures

1995 • 131 citations

Human fetal bone marrow early progenitors for T, B, and myeloid cells are found exclusively in the population expressing high levels of CD34

1994 • 122 citations

Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro

1989 • 121 citations

Differential roles of stromal cells, interleukin-7, and kit-ligand in the regulation of B lymphopoiesis

1992 • 120 citations

Hematopoietic potential of cryopreserved and ex vivo manipulated umbilical cord blood progenitor cells evaluated in vitro and in vivo

1996 • 104 citations

The growth response to IL-7 during normal human B cell ontogeny is restricted to B-lineage cells expressing CD34.

1995 • 99 citations

Development of a bone marrow culture for maintenance and growth of normal human B cell precursors.

1991 • 97 citations

Resident bone marrow macrophages produce type 1 interferons that can selectively inhibit interleukin-7-driven growth of B lineage cells

1995 • 95 citations

Immunoglobulin recombinase gene activity is modulated reciprocally by interleukin 7 and CD19 in B cell progenitors.

1995 • 90 citations

The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal- cell-independent expansion and differentiation of human fetal pro-B cells in vitro

1996 • 90 citations

Long-term culture system for selective growth of human B-cell progenitors.

1995 • 82 citations

Engraftment of human hematopoietic precursor cells with secondary transfer potential in SCID-hu mice

1994 • 80 citations

Myofibroblastic stromal cells isolated from human bone marrow induce the proliferation of both early myeloid and B-lymphoid cells

1993 • 74 citations

In vitro differentiation of B lymphocytes from primitive hemopoietic precursors present in long-term bone marrow cultures.

1986 • 73 citations

Reconstitution of SCID mice with human lymphoid and myeloid cells after transplantation with human fetal bone marrow without the requirement for exogenous human cytokines.

1994 • 68 citations

In vitro T lymphopoiesis of human and rhesus CD34+ progenitor cells

1996 • 57 citations

Human allogeneic stem cell maintenance and differentiation in a long- term multilineage SCID-hu graft

1995 • 56 citations

Cytokine regulation of early human lymphopoiesis.

1994 • 56 citations

Hydrocortisone differentially affects the ability of murine stromal cells and human marrow-derived adherent cells to promote the differentiation of CD34++/CD38- long-term culture-initiating cells

1994 • 56 citations

Characterization of early B lymphocyte precursors present in long-term bone marrow cultures.

1983 • 49 citations

Myofibroblastic stromal cells isolated from human bone marrow induce the proliferation of both early myeloid and B-lymphoid cells

1993 • 48 citations

Use of scid mice to identify and quantitate lymphoid-restricted stem cells in long-term bone marrow cultures

1989 • 47 citations

In vitro development of B lymphocytes from long-term cultured precursor cells.

1986 • 42 citations

Cell surface expression of surrogate light chain (ΨL) in the absence of μ on human pro‐B cell lines and normal pro‐B cells

1996 • 33 citations

Long-term cultured B lymphocytes and their precursors reconstitute the B-lymphocyte lineage in vivo.

1984 • 32 citations

Growing human B-cell precursors in vitro: the continuing challenge

1989 • 31 citations

B4B, a novel growth-arrest gene, is expressed by a subset of progenitor/pre-B lymphocytes negative for cytoplasmic mu-chain.

1996 • 26 citations

B-lineage colonies from normal, human bone marrow are initiated by B cells and their progenitors

1991 • 18 citations

B-lineage colonies from normal, human bone marrow are initiated by B cells and their progenitors

1991 • 11 citations

The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal- cell-independent expansion and differentiation of human fetal pro-B cells in vitro

1996 • 11 citations