The transport of neurotransmitters into synaptic vesicles

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

1983 • 4,822 citations

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity.

1985 • 1,253 citations

Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

1984 • 1,007 citations

Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter

1991 • 928 citations

Cloning and Expression of a Rat Brain GABA Transporter

1990 • 873 citations

Cloning and expression of a functional serotonin transporter from rat brain

1991 • 822 citations

Cloning of a Serotonin Transporter Affected by Antidepressants

1991 • 613 citations

A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter

1992 • 594 citations

Cloning and Expression of a Cocaine-Sensitive Rat Dopamine Transporter

1991 • 587 citations

Cloning and Expression of a Cocaine-Sensitive Dopamine Transporter Complementary DNA

1991 • 584 citations

Characterization of Glutamate Uptake into Synaptic Vesicles

1985 • 437 citations

Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors

1992 • 428 citations

Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: A mechanism of action

1990 • 380 citations

Efflux-mediated multidrug resistance in Bacillus subtilis: similarities and dissimilarities with the mammalian system.

1991 • 367 citations

Cloning and functional characterization of a cocaine‐sensitive dopamine transporter

1991 • 362 citations

Glutamate uptake by brain synaptic vesicles. Energy dependence of transport and functional reconstitution in proteoliposomes.

1988 • 357 citations

Depolarization Without Calcium Can Release γ-Aminobutyric Acid from a Retinal Neuron

1987 • 352 citations

Accumulation of biological amines into chromaffin granules: a model for hormone and neurotransmitter transport

1988 • 323 citations

The evolution of H+-ATPases

1989 • 313 citations

Synaptic vesicles immunoisolated from rat cerebral cortex contain high levels of glutamate

1989 • 297 citations

The synaptic vesicle protein SV2 is a novel type of transmembrane transporter

1992 • 257 citations

Molecular cloning and expression of a high affinity l -proline transporter expressed in putative glutamatergic pathways of rat brain

1992 • 239 citations

Adenosine triphosphate-dependent uptake of glutamate into protein I-associated synaptic vesicles.

1983 • 206 citations

GABA and glycine in synaptic vesicles: storage and transport characteristics

1991 • 191 citations

Uptake of GABA by rat brain synaptic vesicles isolated by a new procedure.

1988 • 174 citations

Vaccinia-T7 RNA polymerase expression system: Evaluation for the expression cloning of plasma membrane transporters

1991 • 157 citations

ATP-Driven H+ Pumping into Intracellular Organelles

1986 • 154 citations

Metal-tetracycline/H+ antiporter of Escherichia coli encoded by a transposon, Tn10. The role of the conserved dipeptide, Ser65-Asp66, in tetracycline transport.

1990 • 150 citations

Proton gradient linkage to active uptake of [3H]acetylcholine by Torpedo electric organ synaptic vesicles

1982 • 135 citations

Uptake of γ‐Aminobutyric Acid by a Synaptic Vesicle Fraction Isolated from Rat Brain

1988 • 134 citations

Reserpine binding to bovine chromaffin granule membranes. Characterization and comparison with dihydrotetrabenazine binding.

1984 • 127 citations

One-step purification of Escherichia coli H(+)-ATPase (F0F1) and its reconstitution into liposomes with neurotransmitter transporters.

1991 • 124 citations

Energy dependence and functional reconstitution of the gamma-aminobutyric acid carrier from synaptic vesicles.

1990 • 122 citations

Sequence homology between the tetracycline-resistance determinants of Tn10 and pBR322

1983 • 122 citations

Active transport of gamma-aminobutyric acid and glycine into synaptic vesicles.

1989 • 119 citations

Demonstration of a receptor in Torpedo synaptic vesicles for the acetylcholine storage blocker L-trans-2-(4-phenyl[3,4-3H]-piperidino) cyclohexanol.

1986 • 116 citations

Structure of the 116-kDa polypeptide of the clathrin-coated vesicle/synaptic vesicle proton pump

1991 • 116 citations

Dihydrotetrabenazine Binding and Monoamine Uptake in Mouse Brain Regions

1986 • 100 citations

Nucleotide sequence analysis reveals similarities between proteins determining methylenomycin A resistance in Streptomyces and tetracycline resistance in eubacteria

1987 • 93 citations

Energetics of reserpine binding and occlusion by the chromaffin granule biogenic amine transporter

1990 • 90 citations

A Mg<sup>++</sup>-ATP Dependent Storage Mechanism in the Amine Granules of the Adrenal Medulla

1962 • 88 citations

Reserpine binding to chromaffin granules suggests the existence of two conformations of the monoamine transporter

1989 • 86 citations

Evidence that the blockade of mitochondrial respiration by the neurotoxin 1-methyl-4-phenylpyridinium (MPP+) involves binding at the same site as the respiratory inhibitor, rotenone

1990 • 86 citations

Ketanserin binds to the monoamine transporter of chromaffin granules and of synaptic vesicles.

1988 • 83 citations

Characterization of the solubilized and reconstituted ATP-dependent vesicular glutamate uptake system

1989 • 72 citations

Energetics of tetracycline efflux system encoded by Tn10 in Escherichia coli

1985 • 71 citations

β-galactoside transport in E. coli: a functional dissection of lac permease

1990 • 70 citations

Identification and purification of a functional amine transporter from bovine chromaffin granules.

1990 • 69 citations

Phylogenetic studies on the synaptic vesicle glutamate transport system

1991 • 60 citations

Conditions required for reserpine binding to the catecholamine transporter on chromaffin granule ghosts

1982 • 55 citations

Uptake of Glycine into Synaptic Vesicles Isolated from Rat Spinal Cord

1990 • 55 citations

Solubilization and reconstitution of the catecholamine transporter from bovine chromaffin granules

1979 • 48 citations

Cholinergic Synaptic Vesicles Contain a V‐Type and a P‐Type ATPase

1989 • 45 citations

Photoinactivation and identification of the biogenic amine transporter in chromaffin granules from bovine adrenal medulla.

1982 • 38 citations

Time required for transmitter accumulation inside monoaminergic storage vesicles differs in peripheral and in central systems

1988 • 37 citations

A functional reconstitution of the .gamma.-aminobutyric acid transporter from synaptic vesicles using artificial ion gradients

1991 • 36 citations

Cholinergic synaptic vesicle heterogeneity: evidence for regulation of acetylcholine transport

1988 • 35 citations

Bacteriorhodopsin drives the glutamate transporter of synaptic vesicles after co-reconstitution.

1990 • 33 citations

Characterization and purification of the monoamine transporter of bovine chromaffin granules

1992 • 33 citations

Purification and Characterization of a Nonvesicular Vesamicol‐Binding Protein from Electric Organ and Demonstration of a Related Protein in Mammalian Brain

1991 • 31 citations

Photoaffinity labeling of the tetrabenazine binding sites of bovine chromaffin granule membranes

1985 • 28 citations

Covalent modification of the amine transporter with N,N'-dicyclohexylcarbodiimide

1991 • 23 citations

Induction of the vesicular monoamine transporter by elevated potassium concentration in cultures of rat sympathetic neurons

1990 • 21 citations

Purification of a [3H]dihydrotetrabenazine-binding protein from bovine adrenal medulla.

1991 • 20 citations