The Roles of Transport and Phosphorylation in Nutrient Uptake in Cultured Animal Cells

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆I. Nomenclature and rate equations

1963 • 2,095 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

1963 • 1,885 citations

The Movement of Molecules Across Cell Membranes

1967 • 1,196 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆II. Inhibition: Nomenclature and theory

1963 • 865 citations

Regulation in metabolism

1973 • 780 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

1963 • 774 citations

Regulation in Metabolism

1974 • 607 citations

SUBSTRATE SPECIFICITY OF BRAIN HEXOKINASE

1954 • 595 citations

The Role of Adenosine and 2'-Deoxyadenosine in Mammalian Cells

1978 • 518 citations

Incorporation of 3H-uridine and 3H-uracil into RNA

1974 • 485 citations

Multiple Hexokinases of Rat Tissues

1966 • 483 citations

Methods in Membrane Biology

1978 • 417 citations

The Biological Significance of Purine Salvage

1971 • 406 citations

Difference in the Cyclic Adenosine 3′,5′-Monophosphate Levels in Normal and Transformed Cells

1972 • 396 citations

High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase

1977 • 378 citations

Transport of nucleosides, nucleic acid bases, choline and glucose by animal cells in culture

1974 • 338 citations

Transport of sugars in tumor cell membranes

1974 • 338 citations

The Pasteur effect and the relations between respiration and fermentation.

1972 • 302 citations

TRANSPORT CHANGES RAPIDLY INITIATED BY SERUM ADDITION TO “CONTACT INHIBITED” 3T3 CELLS

1969 • 285 citations

A Unifying Hypothesis Concerning the Nature of Malignant Growth

1972 • 282 citations

Hexose Transport in Normal and in Rous Sarcoma Virus-transformed Cells

1973 • 281 citations

Increased Uptake of Amino Acids and 2-Deoxy-D-Glucose by Virus-Transformed Cells in Culture

1972 • 277 citations

Reciprocal regulation of glucose and glutamine utilization by cultured human diploid fibroblasts

1978 • 274 citations

Bioenergetics and the problem of tumor growth.

1972 • 240 citations

The molecular biology of the mammalian genetic apparatus

1977 • 239 citations

Über den Stoffwechsel der Tumoren : Arbeiten aus dem Kaiser Wilhelm Institut für Biologie, Berlin- Dahlem

1926 • 235 citations

Concentrations of Metabolites and Binding Sites. Implications in Metabolic Regulation

1970 • 228 citations

Mediated transport of nucleosides in human erythrocytes. Specific binding of the inhibitor nitrobenzylthioinosine to nucleoside transport sites in the erythrocyte membrane

1974 • 224 citations

The Warburg hypothesis fifty years later

1976 • 218 citations

Permeation of Glucose by Simple and Facilitated Diffusion by Novikoff Rat Hepatoma Cells in Suspension Culture and Its Relationship to Glucose Metabolism

1972 • 215 citations

The effect of flavonoids on aerobic glycolysis and growth of tumor cells.

1975 • 211 citations

Deoxycytidine kinase from calf thymus. Substrate and inhibitor specificity.

1976 • 209 citations

Transport and metabolism of deoxycytidine and 1-beta-D-arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation, and regulation of triphosphate synthesis.

1978 • 197 citations

The Inhibition of Sugar Transport in Chick Embryo Fibroblasts by Cytochalasin B

1973 • 196 citations

Scientific Foundations of Oncology

1976 • 196 citations

Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. I. Kinetics of incorporation of nucleosides into nucleotide pools and pool sizes during growth cycle

1971 • 181 citations

Enzyme patterns in fetal, adult and neoplastic rat tissues

1976 • 180 citations

Stimulation of Glucose Transport in Cultures of Density-Inhibited Chick Embryo Cells

1971 • 177 citations

Inherited disorder of purine metabolism. Correlation between central nervous system dysfunction and biochemical defects

1967 • 172 citations

Effect of Phytohemagglutinin on Lymphocyte Membrane Transport

1971 • 169 citations

Nucleotide Metabolism: An Introduction

1973 • 169 citations

Pleiotypic Control by Adenosine 3′:5′-Cyclic Monophosphate: A Model for Growth Control in Animal Cells

1973 • 166 citations

Pleiotypic Control by Cyclic AMP: Interaction with Cyclic GMP and Possible Role of Microtubules

1973 • 165 citations

Concentrative Accumulation of Choline by Human Erythrocytes

1968 • 164 citations

Multiple molecular forms of ATP: Hexose 6-phosphotransferase from rat liver

1964 • 163 citations

Properties of Deoxythymidine Kinase Partially Purified from Animal Tumors

1965 • 161 citations

Sugar Transport in Chick Embryo Fibroblasts

1974 • 160 citations

Hexose Transport in Isolated Brown Fat Cells

1974 • 159 citations

Some Properties of Partially Purified Mammalian Adenosine Kinase

1967 • 159 citations

Nucleoside Transport. I. A Mediated Process in Human Erythrocytes

1971 • 158 citations

Testing and characterizing the simple carrier

1974 • 152 citations

Kinetic Studies of Hypoxanthine-Guanine Phosphoribosyltransferase

1968 • 150 citations

Membrane molecular biology of neoplastic cells

1975 • 149 citations

Mediated Transport of Nucleosides in Human Erythrocytes

1972 • 146 citations

Permeation as the rate-limiting step in the phosphorylation of urdine and choline and their incorporation into macromolecules by Novikoff hepatoma cells. Competitive inhibition by phenethyl alcohol, persantin, and adenosine

1969 • 145 citations

STUDIES OF TISSUE PERMEABILITY

1957 • 142 citations

Studies of the glucose-transport system in the rabbit erythrocyte

1964 • 140 citations

Membrane Transport of Purine and Pyrimidine Bases and Nucleosides in Animal Cells

1975 • 138 citations

An analysis of the assay of rous sarcoma cells in vitro by the infective center technique

1960 • 138 citations

Cytochalasin B and the kinetics of inhibition of biological transport. A case of asymmetric binding to the glucose carrier

1978 • 137 citations

Exchange of 3-O-methylglucose in isolated fat cells. Concentration dependence and effect of insulin.

1976 • 137 citations

Chapter 16 A Rapid-Mixing Technique to Measure Transport in Suspended Animal Cells: Applications to Nucleoside Transport in Novikpff Rat Hepatoma Cells

1978 • 135 citations

Deoxycytidine Kinase

1970 • 133 citations

Differential effects of sulfhydryl reagents on activation and deactivation of the fat cell hexose transport system.

1976 • 132 citations

The periodic synthesis of thymidine kinase in mouse fibroblasts

1966 • 132 citations

On the Significance of Glucolysis for Cancer Growth, With Special Reference to Morris Rat Hepatomas<xref ref-type="fn" rid="FN2">2</xref>

1967 • 131 citations

Nucleotide Biosynthesis from Preformed Purines in Mammalian Cells: Regulatory Mechanisms and Biological Significance

1970 • 131 citations

Inherited Disorder of Purine Metabolism

1967 • 130 citations

Uridine Kinase from Ehrlich Ascites Tumor: Purification and Properties

1960 • 129 citations

Deoxycytidine kinase: properties of the enzyme from human leukemic granulocytes

1975 • 124 citations

Purified multiplication-stimulating activity from rat liver cell conditioned medium: Comparison of biological activities with calf serum, insulin, and somatomedin

1974 • 120 citations

Enhancement of Hexose Entry into Chick Fibroblasts by Starvation: Differential Effect on Galactose and Glucose

1972 • 120 citations

Uridine transport and RNA synthesis in growing and in density‐inhibited animal cells

1971 • 118 citations

Nucleoside Transport. II. Inhibition by p-Nitrobenzylthioguanosine and Related Compounds

1971 • 118 citations

Alterations in the Characteristics of Sugar Uptake by Mouse Cells Transformed by Murine Sarcoma Viruses<xref ref-type="fn" rid="FN2">2</xref>

1969 • 115 citations

CYTOCHALASIN B

1972 • 114 citations

Why do tumor cells have a high aerobic glycolysis?

1976 • 114 citations

THYMIDINE TRANSPORT BY CULTURED NOVIKOFF HEPATOMA CELLS AND UPTAKE BY SIMPLE DIFFUSION AND RELATIONSHIP TO INCORPORATION INTO DEOXYRIBONUCLEIC ACID

1972 • 111 citations

Growth of human diploid fibroblasts in the absence of glucose utilization.

1976 • 105 citations

Nucleoside transport by Novikoff rat hepatoma cells growing in suspension culture

1971 • 104 citations

Neuraminidase stimulates Division and Sugar Uptake in Density-inhibited Cell Cultures

1972 • 103 citations

The surface membrane as a regulator of animal cell division

1971 • 99 citations

The application of rapid kinetic techniques to the transport of thymidine and 3‐O‐methylglucose into mammalian cells in suspension culture

1976 • 99 citations

Thymidine transport in cultured mammalian cells. Kinetic analysis, temperature dependence and specificity of the transport system

1979 • 98 citations

Uridine transport in novikoff rat hepatoma cells and other cell lines and its relationship to uridine phosphorylation and phosphorolysis

1978 • 98 citations

Alterations in Glucose Metabolism in Chick-Embryo Cells Transformed by Rous Sarcoma Virus: Intracellular Levels of Glycolytic Intermediates

1974 • 95 citations

Sugar Transport in Chick Embryo Fibroblasts

1974 • 95 citations

Purine and pyrimidine transport by cultured Novikoff cells. Specificities and mechanism of transport and relationship to phosphoribosylation.

1975 • 94 citations

Regulation of Enzymic Activity by Metabolites

1969 • 94 citations

Kinetics of Early Changes in Phosphate and Uridine Transport and Cyclic AMP Levels Stimulated by Serum in Density-Inhibited 3T3 Cells

1974 • 92 citations

Transport of uridine in human red blood cells. Demonstration of a simple carrier-mediated process.

1977 • 91 citations

Purine transport in polymorphonuclear leukocytes

1969 • 90 citations

Phytohaemagglutinin stimulation of rat thymus lymphocyte glycolysis

1976 • 88 citations

Kinetics of adenosine uptake by erythrocytes, and the influence of dipyridamole.

1972 • 88 citations

Purine and pyrimidine transport and phosphoribosylation and their interaction in overall uptake by cultured mammalian cells. A re-evaluation

1979 • 86 citations

Sugar Transport in Normal and Rous Sarcoma Virus-Transformed Chick-Embryo Fibroblasts

1973 • 85 citations

Combined Immunodeficiency Disease and Adenosine Deaminase Deficiency. A Molecular Defect

1976 • 85 citations

Choline metabolism and membrane formation in rat hepatoma cells grown in suspension culture. III. Choline transport and uptake by simple diffusion and lack of direct exchange with phosphatidylcholine

1971 • 83 citations

The Effect of Insulin on Glucose Transport in Muscle Cells

1975 • 83 citations

Multiple control mechanisms underlie initiation of growth in animal cells

1974 • 82 citations

Ascites Tumor Mitochondrial Hexokinase II

1968 • 81 citations

Purines: supply by liver to tissues

1970 • 77 citations

Sugar Transport in Chick Embryo Fibroblasts

1974 • 77 citations

Transport of two non-metabolized nucleosides, deoxycytidine and cytosine arabinoside, in a sub-line of the L1210 murine leukemia

1968 • 76 citations

Transport and countertransport of thymidine in ATP depleted and thymidine kinase‐deficient novikoff rat hepatoma and mouse L cells: Evidence for a high K_m facilitated diffusion system with wide nucleoside specificity

1976 • 76 citations

Induction of thymidine kinases in phytohaemagglutinin-stimulated human lymphocytes

1977 • 75 citations

Glucose Transport in Fat Cell Membranes

1971 • 73 citations

Stimulation of 2-deoxyglucose uptake in growth-inhibited BALB/c 3T3 and revertant SV40-transformed 3T3 cells

1974 • 73 citations

Patterns of Glucose Metabolism in Normal and Virus-Transformed Chick Cells in Tissue Culture<xref ref-type="fn" rid="FN1">2</xref>

1972 • 73 citations

Properties of the thymidine transport system of chinese hamster ovary cells as probed by nitrobenzylthioinosine

1978 • 73 citations

Growth of cultured mammalian cells on secondary glucose sources

1974 • 72 citations

Alterations in glucose metabolism in chick embryo cells transformed by Rous sarcoma virus

1974 • 71 citations

Transport of sugars in chick-embryo fibroblasts. Evidence for a low-affinity system and a high-affinity system for glucose transport

1976 • 70 citations

The relationship between the transport of glucose and cations across cell membranes in isolated tissues

1969 • 70 citations

Derepression and carrier turnover: Evidence for two distinct mechanisms of hexose transport regulation in animal cells

1976 • 69 citations

Phosphorylation of tritiated thymidine by L929 mouse fibroblasts

1969 • 68 citations

Availability of 5-Phosphoribosyl 1-Pyrophosphate for Ribonucleotide Synthesis in Ehrlich Ascites Tumor Cells in Vitro

1965 • 67 citations

Properties of Deoxycytidine Kinase Partially Purified from L1210 Cells

1968 • 67 citations

Adenosine transport and metabolism in mouse leukemia cells and in canine thymocytes and peripheral blood leukocytes

1979 • 66 citations

Scientific foundations of oncology

1976 • 65 citations

Transport and metabolism of vitamin B6 in rabbit brain and choroid plexus.

1978 • 65 citations

Thiamine intestinal transport

1972 • 64 citations

Mediated transport of nucleosides by human erythrocytes specificity toward purine nucleosides as permeants

1973 • 63 citations

Group translocation of the ribose moiety of inosine by vesicles of plasma membrane from T(3 cells transformed by Simian virus 40.

1976 • 63 citations

Uptake of nucleosides in density-inhibited cultures of 3T3 cells

1977 • 62 citations

�ber die Entstehung der Krebszellen

1955 • 62 citations

Uridine transport and phosphorylation in mouse cells in culture: Effect of growth‐promoting factors, cell cycle transit and oncogenic transformation

1978 • 61 citations

Uptake patterns and transport enhancements in cultures of hamster cells deprived of carbohydrates

1975 • 60 citations

Expression of the Viral Thymidine Kinase Gene in Herpes Simplex Virus-Transformed L Cells

1974 • 60 citations

Phosphorylation but not transport of sugars is enhanced in virus‐transformed mouse 3T3 cells

1975 • 59 citations

Regulation of Sugar Transport in Eukaryotic Cells

1974 • 59 citations

The action of cardiotonic steroids on sugar transport in muscle, in vitro

1968 • 59 citations

Binding of the Nucleoside Transport Inhibitor 4-Nitrobenzylthioinosine to Erythrocyte Membranes

1973 • 59 citations

Deoxyglucose and 3‐O‐methylglucose transport in untreated and ATP‐depleted novikoff rat hepatoma cells. Analysis by a rapid kinetic technique, relationship to phosphorylation and effects of inhibitors

1978 • 58 citations

SV40 Virus Transformation of Mouse 3T3 Cells Does Not Specifically Enhance Sugar Transport

1973 • 57 citations

Growth- and Density-Dependent Inhibition of Deoxyglucose Transport in Balb 3T3 Cells and Its Absence in Cells Transformed by Murine Sarcoma Virus

1973 • 56 citations

Thiamine transport by human intestine in vitro

1977 • 56 citations

Kinetic studies on phosphorylation of 5-azacytidine with the purified uridine-cytidine kinase from calf thymus.

1974 • 56 citations

Alteration of Nucleoside Transport of Chinese Hamster Cells by Dibutyryl Adenosine 3′:5′-Cyclic Monophosphate

1972 • 54 citations

Deoxyglucose transport by uninfected, murihe sarcoma virus-transformed, and murine leukemia virus-infected mouse cells

1973 • 54 citations

Effect of temperature and of cytochalasin B and persantin on the nonmediated permeation of non-electrolytes into cultured Novikoff rat hepatoma cells.

1977 • 54 citations

Inhibition by nitrobenzylthioinosine of adenosine uptake by asynchronous HeLa cells.

1977 • 53 citations

Nucleoside transport in mammalian cell membranes: A specific inhibitory mechanism of high affinity probes

1977 • 52 citations

Alterations in pyrimidine metabolism in L5178Y leukemia cells resistant to 6-azauridine.

1961 • 52 citations

Purification and Properties of Adenylate Pyrophosphorylase from Ehrlich Ascites Tumor Cells

1966 • 51 citations

The effect of endogenous pools of thymidylate on the apparent rate of DNA synthesis

1969 • 51 citations

Effects of actinomycin D and 2-mercapto-1-(β-4-pyridethyl) benzimidazole on the incorporation of [3H]uridine by chick embryo cells

1967 • 51 citations

An Altered Rate of Uridine Transport in Membrane Vesicles Isolated from Growing and Quiescent Mouse 3T3 Fibroblast Cells

1974 • 51 citations

Mammalian Deoxynucleoside Kinases

1971 • 51 citations

Some properties of adenosine kinase from Ehrlich ascites-tumour cells

1968 • 51 citations

Cell cycle and growth stage-dependent changes in the transport of nucleosides, hypoxanthine, choline, and deoxyglucose in cultured Novikoff rat hepatoma cells.

1975 • 48 citations

Two Distinct Types of Enhancement of Galactose Uptake into Hamster Cells: Tumor-Virus Transformation and Hexose Starvation

1973 • 47 citations

Mitogen receptors in chick embryo fibroblasts. Kinetics, specificity, unmasking, and synthesis of 125I-insulin binding sites.

1976 • 47 citations

Activation of 3-O-methyl-glucose transport in rat thymus lymphocytes by concanavalin A temperature and calcium ion dependence and sensitivity to puromycin but not to cycloheximide

1977 • 46 citations

The kinetic dissection of transport from metabolic trapping during substrate uptake by intact cells. Uridine uptake by quiescent and serum-activated nil 8 hamster cells and their murine sarcoma virus-transformed counterparts

1979 • 46 citations

Studies on Choline Permeation through the Plasma Membrane and Its Incorporation into Phosphatidyl Choline of Ehrlich‐Lettré‐Ascites Tumor Cells in vitro

1975 • 46 citations

Hypoxanthine transport in human erythrocytes

1967 • 46 citations

Uptake of 2-deoxyglucose by cells: Changes after polyoma infection

1974 • 46 citations

Virus-transformed cell membranes

1978 • 46 citations

Dynamics of Metabolism of Normal and Virus-Transformed Chick Cells in Culture

1973 • 45 citations

The role of phosphorylation in the uptake of thymidine in mammalian cells

1971 • 45 citations

Chapter 14 A Simplified Method for the Detection of Mycoplasma

1974 • 45 citations

Evidence for the carrier model of transport from the inhibition by N-ethylmaleimide of choline transport across the human red cell membrane

1973 • 45 citations

Changes in the uptake of 2‐deoxy‐D‐glucose in Balb/3T3 cells chemically transformed in culture

1974 • 44 citations

Current status of the thiol redox model for the regulation of hexose transport by insulin

1976 • 44 citations

Uptake of Pyridoxine Hydrochloride by the Rat Jejunal Mucosa in vitro

1977 • 44 citations

Mitogen-stimulated glucose transport in thymocytes. Possible role of Ca++ and antagonism by adenosine 3':5'-monophosphate.

1977 • 44 citations

Application of the isotope-dilution principle to the analysis of factors affecting the incorporation of [3H]uridine and [3H]cytidine into cultured lymphocytes. Evaluation of pools in serum and culture media

1971 • 43 citations

Specific Increase in Pyrimidine Deoxynucleoside Transport at the Time of Deoxyribonucleic Acid Synthesis in 3T3 Mouse Cells

1973 • 43 citations

Evidence against the existence of guanosine and inosine kinases in human fibroblasts in tissue culture

1969 • 42 citations

Reversible independent alterations in glucose transport and metabolism in cultured human cells deprived of glucose

1976 • 42 citations

Uptake of Pyridoxal and Pyridoxal Phosphate by Ehrlich Ascites Tumor Cells

1961 • 41 citations

Kinetics of choline uptake in neuroblastoma clones

1974 • 40 citations

Paradoxical effects of cycloheximide and cytochalasin B on hamster cell hexose uptake.

1976 • 39 citations

Regulation of uridine uptake by serum and insulin in density-inhibited 3T3 cells

1977 • 39 citations

Transport and metabolism of adenosine in human blood platelets

1976 • 39 citations

Interference with nucleoside transport in mouse lymphoma cells proliferating in culture.

1972 • 38 citations

Competitive inhibition of the transport of nucleosides, hypoxanthine, choline and deoxyglucose by theophylline, papaverine and prostaglandins

1974 • 37 citations

2‐Amino‐isobutyric acid and 3‐0‐methyl‐D‐glucose transport in 3T3, SV40‐transformed 3T3 and revertant cell lines

1978 • 37 citations

Cell surface changes and Rous sarcoma virus gene expression in synchronized cells.

1975 • 37 citations

Hexose transport regulation in cultured hamster cells

1977 • 37 citations

The pH-dependence of sugar-transport and glycolysis in cultured Ehrlich ascites-tumour cells

1978 • 36 citations

Transport of a nonphosphorylated nucleoside, 5'-deoxyadenosine, by murine leukemia L1210 cells.

1978 • 36 citations

The Significance of Glycolysis<xref ref-type="fn" rid="FN2">2</xref>

1965 • 36 citations

Saturable and nonsaturable hexose uptake in cultured human skin fibroblasts

1978 • 36 citations

Carbohydrate Catabolism and the Enhancement of Uptake of Galactose in Hamster Cells Transformed by Polyoma Virus

1973 • 35 citations

Adenine nucleotide metabolism of blood platelets. VIII. Transport of adenine into human platelets

1973 • 33 citations

Rat Skeletal Muscle Hexokinase

1965 • 33 citations

Formation of Inosine-5'-Monophosphate by a Kinase in Cell-Free Extracts of Ehrlich Ascites Cells in Vitro

1968 • 33 citations

Kinetics of 3-O-methyl glucose transport in red blood cells of newborn pigs.

1976 • 33 citations

Inhibition of uridine uptake in HeLa cells by nitrobenzylthioinosine and related compounds.

1977 • 32 citations

Regulation of amino acid and glucose transport activity expressed in isolated membranes from untransformed and SV 40-transformed mouse fibroblasts

1976 • 32 citations

A new approach in the kinetics of biological transport the potential of reversible inhibition studies

1978 • 32 citations

Transport as a rate limiting step in glucose metabolism in virus‐transformed cells: Studies with cytochalasin B

1976 • 32 citations

TRANSPORT INHIBITORS RELEASED BY 3T3 MOUSE CELLS AND THEIR RELATION TO GROWTH CONTROL

1971 • 31 citations

Uridine kinase: properties, biological significance and chemotherapeutic aspects (a review).

1976 • 30 citations

Regulation of sugar transport in chick embryo fibroblasts infected with a temperature-sensitive mutant of RSV

1975 • 29 citations

Thymidine transport in phytohaemagglutinin-stimulated pig lymphocytes

1975 • 29 citations

Inhibition of thymidine uptake in asynchronous HeLa cells by nitrobenzylthioinosine*1

1977 • 29 citations

Purification and properties of thymidine kinase from regenerating rat liver

1974 • 29 citations

Determination of 5-phosphoribosyl 1-pyrophosphate in mouse liver

1974 • 28 citations

Active transport of thiamine by freshly isolated rat hepatocytes.

1978 • 28 citations

Uridine transport properties of mammalian cell membranes are not directly involved with growth control or oncogenesis

1978 • 28 citations

Rat Skeletal Muscle Hexokinase

1967 • 28 citations

Isotope-dilution analysis of rate-limiting steps and pools affecting the incorporation of thymidine and deoxycytidine into cultured thymus cells

1974 • 28 citations

Is glucose transport enhanced in virus‐transformed mammalian cells? A dissenting view

1976 • 27 citations

Relationship between thymidine transport and phosphorylation in Novikoff rat hepatoma cells as analyzed by a rapid sampling technique

1977 • 26 citations

Regulation of sugar transport in chick embryo fibroblasts and in fibroblasts transformed by a temperature‐sensitive mutant of the rous sarcoma virus

1976 • 25 citations

Regulation of cell division and malignant transformation: A new model for control by uptake of nutrients

1977 • 25 citations

Studies on the mechanism of serum stimulation of uridine uptake in serum-less mouse cells

1972 • 25 citations

Hexose uptake and control of fibroblast proliferation

1977 • 25 citations

Effect of cAMP on nucleoside metabolism. I. Effect on thymidine transport and incorporation in monkey cells (CV‐1)

1974 • 25 citations

[74] Hypoxanthine phosphoribosyltransferase from Chinese hamster brain and human erythrocytes

1978 • 25 citations

Stimulation of lactic acid production in chick embryo fibroblasts by serum and high pH in the absence of external glucose

1975 • 24 citations

Sugar-transport kinetics of the rat thymocyte

1977 • 24 citations

Testing transport models with substrates and reversible inhibitors

1978 • 24 citations

A Kinetic Analysis of the Uptake of Cytosine‐β‐<scp>d</scp>‐Arabinoside by Rat‐B77 Cells

1979 • 24 citations

Transport enhancement and reversal: Glucose and 3‐O‐methyl glucose

1977 • 24 citations

Hypoxanthine phosphoribosyltransferase activity in normal, developing, and neoplastic tissues of the rat

1975 • 24 citations

The mechanism of interaction between high-affinity probes and the uridine transport system of mammalian cells

1976 • 23 citations

METABOLISM OF ASCITES TUMOR CELLS. II. INHIBITION OF RESPIRATION BY GLYCOLYZABLE AND NONGLYCOLYZABLE SUGARS PHOSPHORYLATED BY HEXOKINASE.

1964 • 21 citations

A labile serum-dependent uridine uptake function in mouse embryo cells

1972 • 21 citations

On the stimulation of rat thymocyte 3‐0‐methyl‐glucose transport by mitogenic stimuli

1978 • 20 citations

Differences in cytochalasin B inhibition of 3‐O‐methylglucose uptake between BALB/3T3 cells and a murine sarcoma virus transformed clone

1973 • 20 citations

Saturable and nonsaturable process of sugar uptake: Effect of oncogenic transformation in transport and uptake of nutrients

1976 • 20 citations

Glycolysis and Respiration of Transformed BHκ2I Cells

1964 • 20 citations

Stimulation of uridine uptake in 3T3 cells is associated with increased ATP affinity of uridine-phosphorylating system

1978 • 20 citations

Increased membrane transport of 2‐deoxyglucose and 3‐0‐methylglucose is an early event in the transformation of chick embryo fibroblasts by rous sarcoma virus

1978 • 20 citations

Temperature-dependent alterations in 2-deoxyglucose uptake in rat cells transformed by a cold-sensitive murine sarcoma virus mutant

1973 • 20 citations

Magnesium and calcium effects on uptake of hexoses and uridine by chick embryo fibroblasts.

1977 • 19 citations

The Effect of Oxidative Metabolic Substrates on the Membrane Transport of Sugars and on the Action of Ouabain in Skeletal Muscle In Vitro

1973 • 18 citations

Transport of thymidine during the cell cycle in mitotically synchronized CHO cells

1975 • 18 citations

D-xylose and xylitol: Previously unrecognized sole carbon and energy sources for chick and mammalian cells

1976 • 17 citations

Growth rate of cultured Novikoff rat hepatoma cells as a function of the rate of thymidine and hypoxanthine transport

1977 • 17 citations

Sodium concentrations affect metabolite uptake and cellular metabolism

1978 • 17 citations

Comparative Studies in Rous Sarcoma. IV. Glucose Metabolism of Normal and Rous Sarcoma Virus-Infected Cells.

1963 • 17 citations

Temperature dependence of uridine transport in quiescent and serum-stimulated 3T3 cells

1976 • 15 citations

Uracil phosphoribosyl transferase activity of mycoplasma and infected cell cultures

1977 • 15 citations

Two distinct states of sugar transport system in cultures of BHK cells

1976 • 14 citations

Glycolytic enzyme activities in murine sarcoma virus-transformed cultures of Balb 3T3

1976 • 14 citations

Regulation of glucose transport in chick fibroblasts: Bicarbonate, lactate and ascorbic acid

1976 • 14 citations

New prospects in cancer biochemistry

1963 • 14 citations

Inhibition of transport systems in cultured rat hepatoma cells by colcemid and ethanol

1974 • 14 citations

Glucose transport and metabolism in cultured cells of nervous tissue

1976 • 13 citations

Growth of chick and mammalian cells on d-xylose

1977 • 12 citations

Density-dependent changes in hexose transport, glycolytic enzyme levels, and glycolytic rates, in uninfected and murine sarcoma virus-transformed rat kidney cells

1977 • 12 citations

[79] Adenine phosphoribosyltransferase from rat liver

1978 • 11 citations

Metabolic stability of the nucleoside transport system of novikoff rat hepatoma cells

1978 • 11 citations

Uptake of exogenous metabolites by virus-transformed cells: Changes induced by temperature and pH

1976 • 10 citations

Guanosine anabolism for biosynthesis of nucleic acids in Novikoff ascites rat tumor cells in culture.

1973 • 10 citations

Distinct properties of uridine transport systems in growing, quiescent and serum-stimulated hamster embryo cells

1977 • 10 citations

Deoxycytidine transport and pyrimidine deoxynucleotide metabolism in phytohaemagglutinin-stimulated pig lymphocytes

1976 • 9 citations

Effect of actinomycin D on uptake and incorporation of thymidine and hypoxanthine into the acid-soluble and acid-insoluble fractions of rat hepatoma cells grown in culture

1974 • 8 citations

Transformed BHK cells exhibiting normal or subnormal sugar uptake

1977 • 8 citations

Zur Bedeutung der Glucose f�r Energielieferung und Nucleotidgehalt in Ehrlich-Ascitestumorzellen

1972 • 1 citations