Uridine transport in novikoff rat hepatoma cells and other cell lines and its relationship to uridine phosphorylation and phosphorolysis

Statistical estimations in enzyme kinetics

1961 • 3,586 citations

The concept of carrier transport and its corollaries in pharmacology.

1961 • 541 citations

Incorporation of 3H-uridine and 3H-uracil into RNA

1974 • 485 citations

“Pleiotypic Response”

1971 • 415 citations

Transport of nucleosides, nucleic acid bases, choline and glucose by animal cells in culture

1974 • 338 citations

TRANSPORT CHANGES RAPIDLY INITIATED BY SERUM ADDITION TO “CONTACT INHIBITED” 3T3 CELLS

1969 • 285 citations

Permeation of Glucose by Simple and Facilitated Diffusion by Novikoff Rat Hepatoma Cells in Suspension Culture and Its Relationship to Glucose Metabolism

1972 • 215 citations

Transport and metabolism of deoxycytidine and 1-beta-D-arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation, and regulation of triphosphate synthesis.

1978 • 197 citations

Effects of podophyllotoxin and VP-16-213 on microtubule assembly in vitro and nucleoside transport in HeLa cells

1976 • 187 citations

Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. I. Kinetics of incorporation of nucleosides into nucleotide pools and pool sizes during growth cycle

1971 • 181 citations

Pleiotypic Control by Adenosine 3′:5′-Cyclic Monophosphate: A Model for Growth Control in Animal Cells

1973 • 166 citations

Nucleoside Transport. I. A Mediated Process in Human Erythrocytes

1971 • 158 citations

Effect of Phytohemagglutinin on Lymphocyte Membrane Transport

1971 • 155 citations

Mediated Transport of Nucleosides in Human Erythrocytes

1972 • 146 citations

Permeation as the rate-limiting step in the phosphorylation of urdine and choline and their incorporation into macromolecules by Novikoff hepatoma cells. Competitive inhibition by phenethyl alcohol, persantin, and adenosine

1969 • 145 citations

Membrane Transport of Purine and Pyrimidine Bases and Nucleosides in Animal Cells

1975 • 138 citations

Fluctuations of DNA‐dependent RNA polymerase and synthesis of macromolecules during the growth cycle of Novikoff rat hepatoma cells in suspension culture

1969 • 136 citations

Chapter 16 A Rapid-Mixing Technique to Measure Transport in Suspended Animal Cells: Applications to Nucleoside Transport in Novikpff Rat Hepatoma Cells

1978 • 135 citations

NUCLEOTIDE POOLS IN NOVIKOFF RAT HEPATOMA CELLS GROWING IN SUSPENSION CULTURE

1972 • 127 citations

Transport changes in synchronously growing CHO and L cells

1972 • 124 citations

Regulation of Escherichia coli phosphofructokinase in situ

1973 • 119 citations

Uridine transport and RNA synthesis in growing and in density‐inhibited animal cells

1971 • 118 citations

The Kinetics of Selective Biological Transport

1968 • 110 citations

Kinetic Studies of Transport Across Red Blood Cell Membranes

1974 • 106 citations

The application of rapid kinetic techniques to the transport of thymidine and 3‐O‐methylglucose into mammalian cells in suspension culture

1976 • 99 citations

Membrane transport of nucleosides in rabbit polymorphonuclear leukocytes

1972 • 98 citations

Regulation of Enzymic Activity by Metabolites

1969 • 94 citations

Purine and pyrimidine transport by cultured Novikoff cells. Specificities and mechanism of transport and relationship to phosphoribosylation.

1975 • 94 citations

Kinetics of Early Changes in Phosphate and Uridine Transport and Cyclic AMP Levels Stimulated by Serum in Density-Inhibited 3T3 Cells

1974 • 92 citations

Magnesium deprivation reproduces the coordinate effects of serum removal or cortisol addition on transport and metabolism in chick embryo fibroblasts

1976 • 81 citations

Transport and countertransport of thymidine in ATP depleted and thymidine kinase‐deficient novikoff rat hepatoma and mouse L cells: Evidence for a high K_m facilitated diffusion system with wide nucleoside specificity

1976 • 76 citations

Properties of the thymidine transport system of chinese hamster ovary cells as probed by nitrobenzylthioinosine

1978 • 73 citations

Uptake of nucleosides in density-inhibited cultures of 3T3 cells

1977 • 62 citations

Binding of the Nucleoside Transport Inhibitor 4-Nitrobenzylthioinosine to Erythrocyte Membranes

1973 • 59 citations

Deoxyglucose and 3‐O‐methylglucose transport in untreated and ATP‐depleted novikoff rat hepatoma cells. Analysis by a rapid kinetic technique, relationship to phosphorylation and effects of inhibitors

1978 • 58 citations

Alteration of Nucleoside Transport of Chinese Hamster Cells by Dibutyryl Adenosine 3′:5′-Cyclic Monophosphate

1972 • 54 citations

Deoxyglucose transport by uninfected, murihe sarcoma virus-transformed, and murine leukemia virus-infected mouse cells

1973 • 54 citations

Effect of temperature and of cytochalasin B and persantin on the nonmediated permeation of non-electrolytes into cultured Novikoff rat hepatoma cells.

1977 • 54 citations

TRANSPORT OF NUCLEOSIDES^*

1975 • 53 citations

Nucleoside transport in mammalian cell membranes: A specific inhibitory mechanism of high affinity probes

1977 • 52 citations

An Altered Rate of Uridine Transport in Membrane Vesicles Isolated from Growing and Quiescent Mouse 3T3 Fibroblast Cells

1974 • 51 citations

Cell cycle and growth stage-dependent changes in the transport of nucleosides, hypoxanthine, choline, and deoxyglucose in cultured Novikoff rat hepatoma cells.

1975 • 48 citations

Nucleotide pools of novikoff rat hepatoma cells growing in suspension culture. IV. Nucleoside transport in cells depleted of nucleotides by treatment with KCN

1973 • 44 citations

Regulation of uridine uptake by serum and insulin in density-inhibited 3T3 cells

1977 • 39 citations

An Attempted Synthesis of 4,5-Bis(dimethylamino)-1,2,3-thiadiazole

1971 • 36 citations

Binding of [3H]cytochalasin B and its relationship to inhibition of hexose transport in Novkoff rat hepatoma cells.

1977 • 36 citations

Uridine uptake and its intracellular phosphorylation during the cell cycle

1973 • 32 citations

Inhibition of uridine uptake in HeLa cells by nitrobenzylthioinosine and related compounds.

1977 • 32 citations

Uridine kinase: properties, biological significance and chemotherapeutic aspects (a review).

1976 • 30 citations

Inhibition of thymidine uptake in asynchronous HeLa cells by nitrobenzylthioinosine*1

1977 • 29 citations

Membrane transport by macrophages in suspension and adherent to glass

1977 • 27 citations

Relationship between thymidine transport and phosphorylation in Novikoff rat hepatoma cells as analyzed by a rapid sampling technique

1977 • 26 citations

Studies on the mechanism of serum stimulation of uridine uptake in serum-less mouse cells

1972 • 25 citations

Inhibition of nucleoside transport by aflatoxins and sterigmatocystin.

1974 • 24 citations

Uridine kinase activities in normal and neoplastic lymphoid cells.

1977 • 22 citations

Early temporal changes in the uridine kinase isozyme profile of the novikoff hepatoma in response to 5-azacytidine treatment

1975 • 20 citations

Nucleoside Transport in Human Erythrocytes: Equilibrium Exchange Diffusion of Uridine

1972 • 19 citations

Temperature dependence of uridine transport in quiescent and serum-stimulated 3T3 cells

1976 • 15 citations

Metabolic stability of the nucleoside transport system of novikoff rat hepatoma cells

1978 • 11 citations

Distinct properties of uridine transport systems in growing, quiescent and serum-stimulated hamster embryo cells

1977 • 10 citations