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Short-term Fasting as an Enhancer of Chemotherapy: Pilot Clinical Study on Colorectal Carcinoma Patients
NCT04247464
NAINTERVENTIONAL
IMDEA Food
11 participants
Started 2020-09-23 · Completed 2023-02-01
Status: Completed (as of 12-23-2025)
Conditions
Fasting
Interventions
Linked Papers (from SciSciNet-V2)
Total Papers12
Background
10Result
0Derived
0Unknown
2Total Citations Per Year
Brief Summary
This study will evaluate the ability of short-term fasting to reduce chemotherapy toxicity and enhance anti-tumour response in patients with colorectal carcinoma subjected to chemotherapy.
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Background Papers20
Impact of intermittent fasting on health and disease processes
2016
924 citations
Impact of intermittent fasting on health and disease processes
2016
924 citations
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
2008
542 citations
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
2008
542 citations
Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance
2016
444 citations
Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance
2016
444 citations
Fasting and cancer treatment in humans: A case series report
2009
356 citations
Fasting and cancer treatment in humans: A case series report
2009
356 citations
Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity
2016
334 citations
Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity
2016
334 citations
Age and energy intake interact to modify cell stress pathways and stroke outcome
2009
260 citations
Age and energy intake interact to modify cell stress pathways and stroke outcome
2009
260 citations
Effects of intermittent fasting on health markers in those with type 2 diabetes: A pilot study
2017
102 citations
Effects of intermittent fasting on health markers in those with type 2 diabetes: A pilot study
2017
102 citations
Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival
2015
84 citations
Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival
2015
84 citations
Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition
2015
78 citations
Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition
2015
78 citations
p21Cip1 plays a critical role in the physiological adaptation to fasting through activation of PPARα
2016
15 citations
p21Cip1 plays a critical role in the physiological adaptation to fasting through activation of PPARα
2016
15 citations
Result Papers0
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Derived Papers0
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Unknown Papers2
Reversal of Behavioral and Metabolic Abnormalities, and Insulin Resistance Syndrome, by Dietary Restriction in Mice Deficient in Brain-Derived Neurotrophic Factor
2003
179 citations
Fasting induces changes in peripheral blood mononuclear cell gene expression profiles related to increases in fatty acid β-oxidation: functional role of peroxisome proliferator–activated receptor α in human peripheral blood mononuclear cells
2007
122 citations