Pre-adolescent Stress and Health Study

NCT03436706

NULLOBSERVATIONAL

Penn State University

0

Started 2019-01 · Completed 2024-12

Status: Withdrawn (as of 12-23-2025)

Conditions

Stress

Interventions

OTHER: exposure

Linked Papers (from SciSciNet-V2)

Total Papers88

Background

37

Result

0

Derived

0

Unknown

51

View on ClinicalTrials.gov

Total Citations Per Year

Brief Summary

Aim 1: To characterize allostatic load (AL) biomarkers in a sample of low-income early adolescents (N = 225). How many children living in low-income homes have atypical or out-of-range biomarker levels, on which biomarkers, and in what combinations (Aim 1a)? Do AL biomarker elevations predict physical and mental health problems in early adolescence (Aim 1b)? How much and what type of change in AL biomarkers occurs between ages 11 and 14 (Aim 1c)? Aim 2: To investigate in the same sample of early adolescents exposed to varying levels of early life stress (ELS), the relative contributions made by ELS, recent (past year), and cumulative (since age 5) stress exposures to initial AL levels at T1 (Aim 2a), and to changes in AL across the two years of the study (Aim 2b). Aim 3: To explore the extent to which coping resources, including children's coping skills, children's physiologic self-regulation, and parental coping socialization, uniquely and synergistically influence AL levels and accumulations in these early adolescents.

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Background Papers74

The polyvagal perspective

2,913 citations

The polyvagal perspective

2,913 citations

Polyvagal Theory and developmental psychopathology: Emotion dysregulation and conduct problems from preschool to adolescence

Polyvagal Theory and developmental psychopathology: Emotion dysregulation and conduct problems from preschool to adolescence

Psychobiological mechanisms underlying the social buffering of the hypothalamic–pituitary–adrenocortical axis: A review of animal models and human studies across development.

Psychobiological mechanisms underlying the social buffering of the hypothalamic–pituitary–adrenocortical axis: A review of animal models and human studies across development.

Transitions Into Underage and Problem Drinking: Developmental Processes and Mechanisms Between 10 and 15 Years of Age

Transitions Into Underage and Problem Drinking: Developmental Processes and Mechanisms Between 10 and 15 Years of Age

Moderate versus severe early life stress: Associations with stress reactivity and regulation in 10–12-year-old children

Moderate versus severe early life stress: Associations with stress reactivity and regulation in 10–12-year-old children

Early life adversity reduces stress reactivity and enhances impulsive behavior: Implications for health behaviors

Early life adversity reduces stress reactivity and enhances impulsive behavior: Implications for health behaviors

Affective Reactivity to Daily Stressors and Long-Term Risk of Reporting a Chronic Physical Health Condition

Affective Reactivity to Daily Stressors and Long-Term Risk of Reporting a Chronic Physical Health Condition

Comorbidities and continuities as ontogenic processes: Toward a developmental spectrum model of externalizing psychopathology

Comorbidities and continuities as ontogenic processes: Toward a developmental spectrum model of externalizing psychopathology

Income Inequality and Socioeconomic Gradients in Mortality

Income Inequality and Socioeconomic Gradients in Mortality

Childhood adversity and youth depression: Influence of gender and pubertal status

Childhood adversity and youth depression: Influence of gender and pubertal status

Emotion Regulation via the Autonomic Nervous System in Children with Attention-Deficit/Hyperactivity Disorder (ADHD)

Emotion Regulation via the Autonomic Nervous System in Children with Attention-Deficit/Hyperactivity Disorder (ADHD)

Development of Maladaptive Coping: A Functional Adaptation to Chronic, Uncontrollable Stress

Development of Maladaptive Coping: A Functional Adaptation to Chronic, Uncontrollable Stress

Child maltreatment and allostatic load: Consequences for physical and mental health in children from low-income families

Child maltreatment and allostatic load: Consequences for physical and mental health in children from low-income families

Additive contributions of childhood adversity and recent stressors to inflammation at midlife: Findings from the MIDUS study.

Additive contributions of childhood adversity and recent stressors to inflammation at midlife: Findings from the MIDUS study.

Harsh Parenting and Child Externalizing Behavior: Skin Conductance Level Reactivity as a Moderator

Autonomic reactivity in relation to attachment and early adversity among foster children

Autonomic reactivity in relation to attachment and early adversity among foster children

Harsh Parenting and Child Externalizing Behavior: Skin Conductance Level Reactivity as a Moderator

Anxious solitude and peer exclusion predict social helplessness, upset affect, and vagal regulation in response to behavioral rejection by a friend.

Anxious solitude and peer exclusion predict social helplessness, upset affect, and vagal regulation in response to behavioral rejection by a friend.

Early adversity, RSA, and inhibitory control: Evidence of children's neurobiological sensitivity to social context

Early adversity, RSA, and inhibitory control: Evidence of children's neurobiological sensitivity to social context

Marital conflict and growth in children's internalizing symptoms: The role of autonomic nervous system activity.

Marital conflict and growth in children's internalizing symptoms: The role of autonomic nervous system activity.

Stress Generation and Adolescent Depression: Contribution of Interpersonal Stress Responses

Stress Generation and Adolescent Depression: Contribution of Interpersonal Stress Responses

Domestic violence and vagal reactivity to peer provocation

Domestic violence and vagal reactivity to peer provocation

Sex differences in cortisol response to corticotropin releasing hormone challenge over puberty: Pittsburgh Pediatric Neurobehavioral Studies

Sex differences in cortisol response to corticotropin releasing hormone challenge over puberty: Pittsburgh Pediatric Neurobehavioral Studies

Marital conflict, respiratory sinus arrhythmia, and allostatic load: Interrelations and associations with the development of children's externalizing behavior

Marital conflict, respiratory sinus arrhythmia, and allostatic load: Interrelations and associations with the development of children's externalizing behavior

Relational victimization predicts children’s social-cognitive and self-regulatory responses in a challenging peer context.

Mothers as a Resource in Times of Stress: Interactive Contributions of Socialization of Coping and Stress to Youth Psychopathology

Mothers as a Resource in Times of Stress: Interactive Contributions of Socialization of Coping and Stress to Youth Psychopathology

Relational victimization predicts children’s social-cognitive and self-regulatory responses in a challenging peer context.

Skin conductance level reactivity moderates the association between harsh parenting and growth in child externalizing behavior.

Skin conductance level reactivity moderates the association between harsh parenting and growth in child externalizing behavior.

Maternal influences on youth responses to peer stress.

Maternal influences on youth responses to peer stress.

Autonomic arousal in childhood anxiety disorders: Associations with state anxiety and social anxiety disorder

Autonomic arousal in childhood anxiety disorders: Associations with state anxiety and social anxiety disorder

Coping with Stress, Coping with Violence: Links to Mental Health Outcomes Among At-risk Youth

Coping with Stress, Coping with Violence: Links to Mental Health Outcomes Among At-risk Youth

Contributions of maternal adult attachment to socialization of coping

Contributions of maternal adult attachment to socialization of coping

Neurocognitive function and state cognitive stress appraisal predict cortisol reactivity to an acute psychosocial stressor in adolescents

Neurocognitive function and state cognitive stress appraisal predict cortisol reactivity to an acute psychosocial stressor in adolescents

Family and Cultural Influences on Low-Income Latino Children's Adjustment

Family and Cultural Influences on Low-Income Latino Children's Adjustment

Contributions of maternal emotional functioning to socialization of coping

Contributions of maternal emotional functioning to socialization of coping

Maternal Social Coaching Quality Interrupts the Development of Relational Aggression During Early Childhood

Maternal Social Coaching Quality Interrupts the Development of Relational Aggression During Early Childhood

Hostile behavior links negative childhood family relationships to heart rate reactivity and recovery in young adulthood

Unlocking the Black Box: A Multilevel Analysis of Preadolescent Children’s Coping

Unlocking the Black Box: A Multilevel Analysis of Preadolescent Children’s Coping

Hostile behavior links negative childhood family relationships to heart rate reactivity and recovery in young adulthood

The trade-offs of emotional reactivity for youths' social information processing in the context of maternal depression

The trade-offs of emotional reactivity for youths' social information processing in the context of maternal depression

Result Papers0

No result papers linked

Derived Papers0

No derived papers linked

Unknown Papers51

Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication

18,882 citations

The ‘Trier Social Stress Test’ – A Tool for Investigating Psychobiological Stress Responses in a Laboratory Setting

5,649 citations

Socioeconomic disadvantage and child development.

3,592 citations

Coping with stress during childhood and adolescence: Problems, progress, and potential in theory and research.

2,851 citations

The Environment of Childhood Poverty.

2,276 citations

Development of depression from preadolescence to young adulthood: Emerging gender differences in a 10-year longitudinal study.

2,191 citations

The Neurobiology of Stress and Development

1,831 citations

Cumulative risk and child development.

1,553 citations

Vagal tone, development, and Gray's motivational theory: Toward an integrated model of autonomic nervous system functioning in psychopathology

1,398 citations

Responses to stress in adolescence: Measurement of coping and involuntary stress responses.

1,120 citations

The Development of Coping

A multimethodological analysis of cumulative risk and allostatic load among rural children.

Plasma catecholamines and essential hypertension. An analytical review.

Stressors and child and adolescent psychopathology: Evidence of moderating and mediating effects

Social origins of depression: a reply

Exposure to Interparental Conflict and Children's Adjustment and Physical Health: The Moderating Role of Vagal Tone

Stress and the Adolescent Brain

Cumulative risk, maternal responsiveness, and allostatic load among young adolescents.

Cardiac vagal regulation across the preschool period: Stability, continuity, and implications for childhood adjustment

Socioeconomic status and inflammatory processes in childhood asthma: The role of psychological stress

Buffering children from marital conflict and dissolution

A Two-Year Longitudinal Study of Stressful Life Events, Social Support, and Social Problem-Solving Skills: Contributions to Children's Behavioral and Academic Adjustment

Changes in Stress Perception and Coping During Adolescence: The Role of Situational and Personal Factors

Explaining the Link Between Low Socioeconomic Status and Psychopathology: Testing Two Mechanisms of the Social Causation Hypothesis.

Mothers' Social Coaching, Mother-Child Relationship Style, and Children's Peer Competence: Is the Medium the Message?

Coping Socialization in Middle Childhood: Tests of Maternal and Paternal Influences

The interactive effect of marital conflict and stress reactivity on externalizing and internalizing symptoms: The role of laboratory stressors

Maternal anxiety and depression, poverty and marital relationship factors during early childhood as predictors of anxiety and depressive symptoms in adolescence

Socialization of Coping With Community Violence: Influences of Caregiver Coaching, Modeling, and Family Context

The Relations Between Persistent Poverty and Contextual Risk and Children's Behavior in Elementary School.

Vagal tone and temperament as predictors of emotion regulation strategies in young children

Prospective investigation of the effects of socioeconomic disadvantage, life stress, and social support on early adolescent adjustment.

Marital Conflict and Risk for Child Maladjustment over Time: Skin Conductance Level Reactivity as a Vulnerability Factor

Poverty and Health

Effect of Volunteering on Risk Factors for Cardiovascular Disease in Adolescents

Risk and resiliency processes in ethnically diverse families in poverty.

Children's skin conductance reactivity as a mechanism of risk in the context of parental depressive symptoms

Children's affect regulation during a disappointment: Psychophysiological responses and relation to parent history of depression

Testing the Adaptation to Poverty-Related Stress Model: Predicting Psychopathology Symptoms in Families Facing Economic Hardship

Heart rate and skin conductance in four-year-old children with aggressive behavior

A Longitudinal Examination of the Adaptation to Poverty-Related Stress Model: Predicting Child and Adolescent Adjustment Over Time

Cardiovascular Stress Responses in Young Adulthood Associated With Family-of-Origin Relationship Experiences

Physiologic Changes Associated With Violence and Abuse Exposure

The Hpa Axis and the Stress Response

Poverty and involuntary engagement stress responses: examining the link to anxiety and aggression within low-income families

Relational victimization and proactive versus reactive relational aggression: The moderating effects of respiratory sinus arrhythmia and skin conductance

Autonomic reactivity and romantic relational aggression among female emerging adults: Moderating roles of social and cognitive risk

Skin Conductance Level Reactivity Moderates the Association Between Parental Psychological Control and Relational Aggression in Emerging Adulthood

Contributions of Observed Parent Socialization of Coping and Skin Conductance Level Reactivity to Childhood Adjustment

Predicting Heavy Alcohol Use in College Students: Interactions Among Socialization of Coping, Alcohol Use Onset, and Physiological Reactivity