Back to searchBackground Papers4
Result Papers0
Derived Papers0
Unknown Papers8
The Effect of Urea Cream on Sorafenib-associated Hand-Foot Skin Reaction
NCT03212625
PHASE4INTERVENTIONAL
Korea University Guro Hospital
288 participants
Started 2016-01-28 · Completed 2018-09-20
Status: Completed (as of 12-23-2025)
Conditions
Hepatocellular Carcinoma
Interventions
Linked Papers (from SciSciNet-V2)
Total Papers10
Background
2Result
0Derived
0Unknown
8Total Citations Per Year
Brief Summary
Many investigators have studied for prevention and care of Hand-Foot Skin Reaction(HFSR), and urea cream is typical representative. Recent study was performed prevention effect of urea cream for Hand-Foot Skin Reaction(HFSR) on 871 Chinese. But the study did not designed as placebo-control group and it had big defect in double-blinded. Therefore, it needs complementary study as double-blinded placebo-controlled trial and effect of urea cream on Korean patient group.
Sort by:
Background Papers4
Management of hepatocellular carcinoma: An update
2011
7,867 citations
Management of hepatocellular carcinoma: An update
2011
7,867 citations
The Hand-Foot Skin Reaction and Quality of Life Questionnaire: An Assessment Tool for Oncology
2015
37 citations
The Hand-Foot Skin Reaction and Quality of Life Questionnaire: An Assessment Tool for Oncology
2015
37 citations
Result Papers0
No result papers linked
Derived Papers0
No derived papers linked
Unknown Papers8
Sorafenib in Advanced Hepatocellular Carcinoma
2008
11,718 citations
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
2008
5,494 citations
BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis
2004
3,873 citations
Evolving Strategies for the Management of Hand–Foot Skin Reaction Associated with the Multitargeted Kinase Inhibitors Sorafenib and Sunitinib
2008
317 citations
Risk of hand-foot skin reaction with sorafenib: A systematic review and meta-analysis
2008
189 citations
Randomized Controlled Trial of the Prophylactic Effect of Urea-Based Cream on Sorafenib-Associated Hand-Foot Skin Reactions in Patients With Advanced Hepatocellular Carcinoma
2015
129 citations
Meta-analysis of dermatological toxicities associated with sorafenib
2011
58 citations
Sorafenib‐associated hand–foot syndrome in Japanese patients
2010
23 citations