Evolving Strategies for the Management of Hand–Foot Skin Reaction Associated with the Multitargeted Kinase Inhibitors Sorafenib and Sunitinib
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References (50)
Sorafenib in Advanced Hepatocellular Carcinoma
2008 • 11,718 citations
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
1996 • 6,878 citations
Sorafenib in Advanced Hepatocellular Carcinoma
2008 • 5,675 citations
Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma
2007 • 5,572 citations
Sorafenib in Advanced Clear-Cell Renal-Cell Carcinoma
2007 • 4,669 citations
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial
2006 • 2,500 citations
Angiogenesis: an organizing principle for drug discovery?
2007 • 2,179 citations
Sorafenib Blocks the RAF/MEK/ERK Pathway, Inhibits Tumor Angiogenesis, and Induces Tumor Cell Apoptosis in Hepatocellular Carcinoma Model PLC/PRF/5
2006 • 1,431 citations
Safety, Pharmacokinetic, and Antitumor Activity of SU11248, a Novel Oral Multitarget Tyrosine Kinase Inhibitor, in Patients With Cancer
2005 • 1,140 citations
Phase II Placebo-Controlled Randomized Discontinuation Trial of Sorafenib in Patients With Metastatic Renal Cell Carcinoma
2006 • 1,030 citations
Combined inhibition of VEGF‐ and PDGF‐signaling enforces tumor vessel regression by interfering with pericyte‐mediated endothelial cell survival mechanisms
2003 • 598 citations
The hierarchical relationship between activities of daily living and instrumental activities of daily living
1987 • 557 citations
Cutaneous side-effects of kinase inhibitors and blocking antibodies
2005 • 539 citations
Common Terminology Criteria for Adverse Events v3.0 (CTCAE)
2008 • 450 citations
Quality of Life in Patients with Psoriasis: A Systematic Literature Review
2004 • 420 citations
12. Index of ADL
1976 • 339 citations
Antineoplastic Therapy???Induced Palmar Plantar Erythrodysesthesia (???Hand-Foot???) Syndrome
2000 • 279 citations
Expression of c-kit and kit ligand proteins in normal human tissues.
1994 • 260 citations
Kinase Inhibition with BAY 43–9006 in Renal Cell Carcinoma
2004 • 246 citations
Toxicities Associated with the Administration of Sorafenib, Sunitinib, and Temsirolimus and Their Management in Patients with Metastatic Renal Cell Carcinoma
2007 • 235 citations
Hand foot skin reaction in cancer patients treated with the multikinase inhibitors sorafenib and sunitinib
2008 • 229 citations
Development and validation of a quality of life instrument for cutaneous diseases
1997 • 199 citations
Risk of hand-foot skin reaction with sorafenib: A systematic review and meta-analysis
2008 • 189 citations
Hand-foot syndrome associated with liposome-encapsulated doxorubicin therapy
1995 • 173 citations
Hand-foot skin reaction in patients treated with sorafenib: a clinicopathological study of cutaneous manifestations due to multitargeted kinase inhibitor therapy
2007 • 168 citations
Human keratinocytes are a major source of cutaneous platelet-derived growth factor.
1993 • 149 citations
Uncovering Pandora’s vase: the growing problem of new toxicities from novel anticancer agents. The case of sorafenib and sunitinib
2007 • 146 citations
Phase I Trial of Sorafenib in Combination with IFN α-2a in Patients with Unresectable and/or Metastatic Renal Cell Carcinoma or Malignant Melanoma
2007 • 142 citations
Convergent and Discriminant Validity of a Generic and a Disease-Specific Instrument to Measure Quality of Life in Patients with Skin Disease
1997 • 129 citations
Sorafenib and Sunitinib: Novel Targeted Therapies for Renal Cell Cancer
2007 • 115 citations
Dermatological reactions to the multitargeted tyrosine kinase inhibitor sunitinib
2008 • 110 citations
Topical treatment by urea reduces epidermal hyperproliferation and induces differentiation in psoriasis.
1996 • 98 citations
Risk of Hand-Foot Skin Reaction with the Multitargeted Kinase Inhibitor Sunitinib in Patients with Renal Cell and Non–Renal Cell Carcinoma: A Meta-analysis
2009 • 91 citations
Epithelial-Stromal Interactions in Basal Cell Cancer: The PDGF System
1994 • 90 citations
Antiangiogenic Agents: an Update on Small Molecule VEGFR Inhibitors
2007 • 82 citations
Hair Depigmentation Is a Biological Readout for Pharmacological Inhibition of KIT in Mice and Humans
2003 • 78 citations
Inflammation of actinic keratoses subsequent to therapy with sorafenib, a multitargeted tyrosine-kinase inhibitor
2006 • 73 citations
The measurement of Instrumental ADL: Content validity and construct validity
1993 • 63 citations
Spiny keratoderma of the palms and soles
1992 • 60 citations
Early and tardive skin adverse events in chronic myeloid leukaemia patients treated with imatinib
2005 • 60 citations
The pathogenesis of psoriasis and the mechanism of action of tazarotene
1998 • 58 citations
Localized Palmar–Plantar Epidermal Hyperplasia: A Previously Undefined Dermatologic Toxicity to Sorafenib
2007 • 43 citations
Yellow Skin Discoloration Associated with Sorafenib Use for Treatment of Metastatic Renal Cell Carcinoma
2007 • 41 citations
Protein kinase inhibitors in the treatment of renal cell carcinoma: sorafenib
2007 • 35 citations
Managing Side Effects of Angiogenesis Inhibitors in Renal Cell Carcinoma
2007 • 33 citations
Dual targeting of vascular endothelial growth factor (VEGF) with sorafenib and bevacizumab: Clinical and translational results
2007 • 29 citations
Sorafenib: A Promising New Targeted Therapy for Renal Cell Carcinoma
2007 • 24 citations
Hand foot skin reaction (HFSR) by the multikinase inhibitors (MKIs) sorafenib and sunitinib: Impact on quality of life (QoL)
2008 • 22 citations
Bevacizumab, erlotinib, and imatinib in the treatment of patients with advanced renal cell carcinoma: Update of a multicenter phase II trial
2006 • 21 citations
Capecitabine-induced diffuse palmoplantar keratoderma: is it a sequential event of hand?foot syndrome?
2007 • 17 citations
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