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Unknown Papers14
An Investigation of TAS-119 Monotherapy
NCT02448589
PHASE1INTERVENTIONAL
Taiho Oncology, Inc.
74 participants
Started 2014-09 · Completed 2019-08
Status: Terminated (as of 12-23-2025)
Conditions
Advanced Solid Tumors
Interventions
Linked Papers (from SciSciNet-V2)
Total Papers19
Background
5Result
0Derived
0Unknown
14Total Citations Per Year
Brief Summary
A Phase 1, Open-Label, Non-Randomized, Dose-Escalating Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of TAS-119 in Patients with Advanced Solid Tumors.
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Background Papers10
Impact of OATP transporters on pharmacokinetics
2009
893 citations
Impact of OATP transporters on pharmacokinetics
2009
893 citations
Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets
2011
880 citations
Molecular Characterization of Neuroendocrine Prostate Cancer and Identification of New Drug Targets
2011
880 citations
Limitations of the New York Heart Association functional classification system and self-reported walking distances in chronic heart failure
2006
419 citations
Limitations of the New York Heart Association functional classification system and self-reported walking distances in chronic heart failure
2006
419 citations
Expression of Aurora A (but Not Aurora B) Is Predictive of Survival in Breast Cancer
2008
129 citations
Expression of Aurora A (but Not Aurora B) Is Predictive of Survival in Breast Cancer
2008
129 citations
Perimembrane Aurora-A Expression is a Significant Prognostic Factor in Correlation with Proliferative Activity in Non-Small-Cell Lung Cancer (NSCLC)
2007
60 citations
Perimembrane Aurora-A Expression is a Significant Prognostic Factor in Correlation with Proliferative Activity in Non-Small-Cell Lung Cancer (NSCLC)
2007
60 citations
Result Papers0
No result papers linked
Derived Papers0
No derived papers linked
Unknown Papers14
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
2008
25,031 citations
Toxicity and response criteria of the Eastern Cooperative Oncology Group
1982
10,605 citations
2006 Update of Recommendations for the Use of White Blood Cell Growth Factors: An Evidence-Based Clinical Practice Guideline
2006
1,657 citations
AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol
2003
615 citations
Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake
2011
589 citations
Taxanes, microtubules and chemoresistant breast cancer
2007
517 citations
Small Molecule Inhibitors of Aurora-A Induce Proteasomal Degradation of N-Myc in Childhood Neuroblastoma
2013
278 citations
Individual patient data analysis to assess modifications to the RECIST criteria
2008
196 citations
Aurora Kinase A Messenger RNA Overexpression Is Correlated with Tumor Progression and Shortened Survival in Head and Neck Squamous Cell Carcinoma
2006
190 citations
Aurora kinases as targets for cancer therapy
2007
136 citations
Mitotic Checkpoints and Chromosome Instability Are Strong Predictors of Clinical Outcome in Gastrointestinal Stromal Tumors
2011
132 citations
Predictive Value of Aurora-A/STK15 Expression for Late Stage Epithelial Ovarian Cancer Patients Treated by Adjuvant Chemotherapy
2007
68 citations
Quick quantitative analysis of gene dosages associated with prognosis in neuroblastoma
2001
43 citations
Expression of serine threonine kinase 15 is associated with poor differentiation in lung squamous cell carcinoma and adenocarcinoma
2006
34 citations