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Perforated Marginal Ulcer After Gastric Bypass

NCT01041196

NULLOBSERVATIONAL
University of California, San Francisco
30 participants
Started 2009-01 · Completed 2009-12
Status: Completed (as of 12-23-2025)

Conditions

Ulcer Disease After Gastric BypassMarginal UlcerPerforated Marginal UlcerAcutely Perforated Marginal Ulcer

Interventions

Linked Papers (from SciSciNet-V2)

Total Papers41
Background
2
Result
0
Derived
0
Unknown
39

Total Citations Per Year

Brief Summary

A common late complication after gastric bypass surgery is marginal ulceration that is defined as ulcers at the margins of the gastrojejunostomy, mostly on the jejunal side. Most marginal ulcers respond to medical therapy and complicated or complex ulcer disease warrants operative intervention; specifically, perforated, penetrated, obstructing, bleeding and intractable marginal ulcers require surgical intervention. Diverse operative strategies for addressing perforated marginal ulcers after gastric bypass have been described including I) Omental (Graham) patch repair, II) Revision of gastrojejunostomy, III) Irrigation and drainage, IV) any previous procedure with truncal vagotomy, V) Esophagojejunostomy, and VI) Reversal. We formally analyze our experience with the laparoscopic resection and repair of acutely perforated marginal ulcers after Roux-en-Y gastric bypass (RYGB), with or without concomitant resolution of technical risk factors for marginal ulceration.

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Unknown Papers39

Bariatric Surgery
2004
6,671 citations
Prevalence of Overweight and Obesity Among US Children, Adolescents, and Adults, 1999-2002
2004
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Effects of Bariatric Surgery on Mortality in Swedish Obese Subjects
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Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic-ulcer disease: a meta-analysis
2002
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Screening and Interventions for Obesity in Adults: Summary of the Evidence for the U.S. Preventive Services Task Force
2003
618 citations
Complications of the Laparoscopic Roux-en-Y Gastric Bypass: 1,040 Patients - What Have We Learned?
2000
600 citations
Laparoscopic Roux-en-Y Gastric Bypass for Morbid Obesity
2000
378 citations
Effect of alcohol consumption on the gut
2003
352 citations
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1997
317 citations
Marginal Ulcer After Gastric Bypass: A Prospective 3-Year Study of 173 Patients
1998
259 citations
A study on the economic impact of bariatric surgery.
2008
224 citations
Stomal complications of gastric bypass: incidence and outcome of therapy.
1992
197 citations
Gastro-Gastric Fistulas and Marginal Ulcers in Gastric Bypass Procedures for Weight Reduction
1999
196 citations
Pathogenesis of NSAID-induced gastroduodenal mucosal injury
2001
190 citations
Stress-related mucosal disease: Risk factors and prophylactic therapy
2004
137 citations
Weight regain after Roux-en-Y: A significant 20% complication related to PYY
2008
135 citations
Incidence of marginal ulcers and the use of absorbable anastomotic sutures in laparoscopic Roux-en-Y gastric bypass
2006
126 citations
Revisional operations for marginal ulcer after Roux-en-Y gastric bypass
2008
122 citations
Marginal ulcer following gastric bypass for morbid obesity.
1991
112 citations
Stress-related mucosal disease in the critically ill patient: Risk factors and strategies to prevent stress-related bleeding in the intensive care unit
2002
103 citations
An overview of non-cardiac cocaine toxicity
2007
97 citations
Staple Disruption and Marginal Ulceration in Gastric Bypass Procedures for Weight Reduction
1996
91 citations
Toward the Rational and Equitable Use of Bariatric Surgery
2007
83 citations
Prevalence of Helicobacter pylori infection and value of preoperative testing and treatment in patients undergoing laparoscopic Roux-en-Y gastric bypass
2007
80 citations
The Influence of <I>Helicobacter pylori</I> Infection on the Development of Gastric Ulcer in Symptomatic Patients after Bariatric Surgery
2006
55 citations
Perforating marginal ulcers after laparoscopic gastric bypass
2005
51 citations
Alcohol-related diseases of the oesophagus and stomach
2003
41 citations
Clinical observation of the temporal association between crack cocaine and duodenal ulcer perforation
1997
30 citations
Reoperation for marginal ulceration
2007
25 citations
Laparoscopic Revision of the Gastrojejunostomy for Recurrent Bleeding Ulcers after Past Open Revision Gastric Bypass
2006
22 citations
Laparoscopic patching of crack cocaine-induced perforated ulcers.
1996
21 citations
Laparoscopic management of perforated marginal ulcer after laparoscopic Roux-en-Y gastric bypass
2006
16 citations
Giant jejunal ulcers after Roux-en-Y gastric bypass
2008
12 citations
Laparoscopic repair of a perforated marginal ulcer 2 years after gastric bypass
2007
12 citations
Using Radiography to Reveal Chronic Jejunal Ischemia as a Complication of Gastric Bypass Surgery
2003
9 citations
Reoperations and Revisions in Bariatric Surgery
2007
8 citations
Outcomes of Cocaine-Induced Gastric Perforations Repaired With an Omental Patch
2007
6 citations
Warning Patients about Cocaine and Aspirin
1998
0 citations