Behavioral Studies of Genetic Differences in Alcohol Action

Introduction to Quantitative Genetics.

1982 • 22,508 citations

A psychomotor stimulant theory of addiction.

1987 • 2,704 citations

Nebraska Symposium on Motivation

1959 • 2,047 citations

Research Advances in Alcohol and Drug Problems

1984 • 1,126 citations

Alcohol Intoxication and Withdrawal

1976 • 481 citations

Contributions to behavior-genetic analysis : the mouse as a prototype

1970 • 462 citations

Differences in Alcohol Preference among Inbred Strains of Mice

1959 • 453 citations

Genetic Selection for Voluntary Alcohol Consumption in the Albino Rat

1968 • 450 citations

Alcohol tolerance and dependence

1980 • 419 citations

Biphasic action of ethanol

1977 • 373 citations

Estimation of Genetic Correlation: Interpretation of Experiments Using Selectively Bred and Inbred Animals

1990 • 322 citations

Development of the National Institutes of Health Genetically Heterogeneous Rat Stock

1984 • 287 citations

ANIMAL MODELS IN ALCOHOL RESEARCH

1979 • 255 citations

NEW STRAINS OF RATS WITH ALCOHOL PREFERENCE AND NONPREFERENCE

1977 • 241 citations

Alcohol and Aldehyde Metabolizing Systems-IV

1980 • 241 citations

Behavioral evidence for the involvement of γ-aminobutyric acid in the actions of ethanol

1983 • 220 citations

Thirty-two years of selection of rats by ethanol preference: UChA and UChB strains.

1983 • 216 citations

Differential establishment and maintenance of oral ethanol reinforced behavior in Lewis and Fischer 344 inbred rat strains.

1988 • 209 citations

Effect of low dose ethanol on spontaneous motor activity in alcohol-preferring and -nonpreferring lines of rats

1986 • 209 citations

Alcohol Preference and Voluntary Alcohol Intakes of Inbred Rat Strains and the National Institutes of Health Heterogeneous Stock of Rats

1984 • 205 citations

Induction of dependence on ethanol by free-choice drinking in alcohol-preferring rats

1982 • 201 citations

Intragastric Self-Infusion of Ethanol by Ethanol-Preferring and -Nonpreferring Lines of Rats

1984 • 192 citations

Progress toward a voluntary oral consumption model of alcoholism

1979 • 190 citations

Rodent lines selected for factors affecting alcohol consumption.

1987 • 180 citations

Effects of scheduled access on ethanol intake by the alcohol-preferring (P) line of rats

1986 • 179 citations

Currents in Alcoholism.

1978 • 179 citations

A comparison of the effects of alcohol on mice selectively bred for differences in ethanol sleep-time

1974 • 175 citations

Different sensitivities to ethanol in alcohol-preferring and -nonpreferring rats

1982 • 172 citations

Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology

1991 • 171 citations

An evaluation of the locomotor stimulating action of ethanol in rats and mice

1981 • 167 citations

Effect of spontaneous ingestion of ethanol on brain dopamine metabolism

1989 • 163 citations

Brain Sensitivity to Alcohol in Inbred Mouse Strains

1966 • 162 citations

Biphasic effects of ethanol on open-field activity: Sensitivity and tolerance in C57BL/6N and DBA/2N mice.

1982 • 160 citations

The fetal alcohol syndrome in mice: Maternal variables

1980 • 160 citations

The AA and ANA rat lines, selected for differences in voluntary alcohol consumption

1989 • 153 citations

Behavior Genetics: Principles and Applications

1984 • 151 citations

Long and short alcohol deprivation: Effects on AA and P alcohol-preferring rats

1989 • 150 citations

Initial sensitivity and acute tolerance to ethanol in the P and NP lines of rats

1983 • 150 citations

The excitatory effect of ethanol: Absence in rats, no tolerance and increased sensitivity in mice

1986 • 147 citations

Aldehyde Dehydrogenase and Ethanol Preference in Mice

1970 • 145 citations

Effect of hypnotics on mice genetically selected for sensitivity to ethanol

1976 • 145 citations

Genetic factors in alcohol preference of laboratory mice.

1961 • 144 citations

Differences in response to the aversive properties of ethanol in rats selectively bred for oral ethanol preference

1988 • 138 citations

Bidirectional selection for susceptibility to ethanol withdrawal seizures inMus musculus

1985 • 136 citations

LS X SS Recombinant Inbred Strains of Mice: Initial. Characterization

1989 • 132 citations

Genetic correlations among inbred strain sensitivities to convulsions induced by 9 convulsant drugs

1990 • 129 citations

Genetic differences in ethanol drinking of the rat following injection of 6-OHDA, 5,6-DHT or 5,7-DHT into the cerebral ventricles

1976 • 125 citations

Fetal alcohol syndrome in dizygotic twins

1975 • 123 citations

Alcohol consumption in free-feeding rats: procedural, genetic and pharmacokinetic factors

1987 • 119 citations

Factors Underlying Differences in Alcohol Preference of Inbred Strains of Mice

1972 • 119 citations

Polygenic and single-gene determination of responses to ethanol in BXD/Ty recombinant inbred mouse strains.

1983 • 118 citations

The excitatory component of ethanol in mice: A chronic study

1980 • 117 citations

A biometrical genetic analysis of ethanol response in selectively bred Long-Sleep and Short-Sleep mice

1984 • 116 citations

Operant responding for oral ethanol in the alcohol-preferring P and alcohol-nonpreferring NP lines of rats

1989 • 115 citations

Sensitivity to ethanol in inbred mice: Genotypic correlations among several behavioral responses.

1983 • 115 citations

Mouse Strain Differences in Preference for Various Concentrations of Alcohol

1962 • 111 citations

Ethanol withdrawal in mice bred to be genetically prone or resistant to ethanol withdrawal seizures.

1986 • 110 citations

Experimentally Induced Changes in the Free Selection of Ethanol

1960 • 109 citations

Acute dependence on depressant drugs is determined by common genes in mice.

1991 • 109 citations

Characterization of Acute and Chronic Tolerance in Mice Selected for Inherent Differences in Sensitivity to Ethanol

1980 • 104 citations

Sensitivity to ethanol in inbred mice: Genotypic correlations among several behavioral responses.

1983 • 103 citations

Measurement of alcohol preference in genetic experiments.

1964 • 101 citations

Genetic correlations with ethanol withdrawal severity

1983 • 101 citations

Prefrontal cortex lesions differentially disrupt cocaine-reinforced conditioned place preference but not conditioned taste aversion.

1989 • 100 citations

Mice genetically selected for differences in open-field activity after ethanol

1987 • 99 citations

Enzyme activities and ethanol preference in mice

1968 • 98 citations

Tolerance to Ethanol Hypothermia in Inbred Mice: Genotypic Correlations with Behavioral Responses

1982 • 97 citations

Ethanol disordering of spin-labeled mouse brain membranes: correlation with genetically determined ethanol sensitivity of mice.

1982 • 96 citations

Inherited Differences in Intensity of Alcohol Withdrawal Reactions in Mice

1973 • 95 citations

Revitalization of the AA and ANA rat lines: Effects on some line characteristics

1984 • 93 citations

Chronic ethanol tolerance through free-choice drinking in the P line of alcohol-preferring rats

1987 • 93 citations

Neurochemical and operant behavioral studies of a strain of alcohol-preferring rats

1978 • 92 citations

Preabsorptive vs. postabsorptive control of ethanol intake in C57BL/6J and DBA/2J mice

1977 • 91 citations

Acute tolerance in inbred and selected lines of mice

1979 • 91 citations

Selected mouse lines, alcohol and behavior

1989 • 90 citations

Genetic selection for ethanol withdrawal severity: Differences in replicate mouse lines

1983 • 89 citations

Brain regional and adrenal monoamine concentrations and behavioral responses to stress in alcohol-preferring AA and alcohol-avoiding ANA rats

1988 • 88 citations

Assessment of ethanol's hedonic effects in mice selectively bred for sensitivity to ethanol-induced hypothermia

1991 • 87 citations

Evidence for genetic correlation of hypnotic effects and cerebellar Purkinje neuron depression in response to ethanol in mice

1982 • 86 citations

Behavioral sensitivity to purinergic drugs parallels ethanol sensitivity in selectively bred mice

1984 • 86 citations

Response to selection for ethanol-induced locomotor activation: genetic analyses and selection response characterization

1991 • 84 citations

Dissociation of alcohol tolerance and dependence

1976 • 83 citations

Antagonism of the behavioral effects of ethanol by naltrexone in BALB/c, C57BL/6, and DBA/2 mice

1983 • 83 citations

Factors Underlying Differences in Alcohol Preference Among Inbred Strains of Mice

1966 • 82 citations

Genetic Animal Models in the Study of Alcoholism

1989 • 82 citations

Effect of GABAergic drugs on motor impairment from ethanol, barbital and lorazepam in rat lines selected for differential sensitivity to ethanol

1989 • 82 citations

Genetic differences in locomotor activation in mice

1986 • 79 citations

Does tolerance develop to the activating, as well as the depressant, effects of ethanol?

1982 • 78 citations

Ethanol Reinforcement in the Alcohol Nonpreferring Rat: Initiation using Behavioral Techniques without Food Restriction

1989 • 77 citations

Distinctions among sedative, disinhibitory, and ataxic properties of ethanol in inbred and selectively bred mice

1990 • 77 citations

Characteristics of ethanol tolerance in alcohol drinking (AA) and alcohol avoiding (ANA) rats

1988 • 76 citations

Rat strains specially selected for their voluntary alcohol consumption.

1971 • 75 citations

Pharmacology of drug self-administration

1990 • 75 citations

Correlative Analysis of Ethanol‐Related Phenotypes in Rat Inbred Strains

1984 • 75 citations

Alcohol-preferring rats: Genetic sensitivity to alcohol-induced stimulation of dopamine metabolism

1990 • 74 citations

Differential effects of central nervous system depressants in long-sleep and short-sleep mice.

1986 • 73 citations

The development of metabolic tolerance in the alcohol-preferring P rats: Comparison of forced and free-choice drinking of ethanol

1986 • 73 citations

Differences between the sexes in voluntary alcohol consumption and liver ADH-activity in inbred strains of mice

1968 • 72 citations

Sensitivity to low doses of ethanol and pentobarbital in mice selected for sensitivity to hypnotic doses of ethanol.

1976 • 72 citations

Genetic and environmental factors in ethanol self-administration

1987 • 71 citations

Features of environment-dependent tolerance to ethanol

1985 • 70 citations

Ethanol-induced mouse strain differences in locomotor activity

1975 • 69 citations

Heredity of Experimental Alcohol Preference in Rats; II. Coefficient of Heredity

1953 • 68 citations

Effects of convulsants on handling-induced convulsions in mice selected for ethanol withdrawal severity

1991 • 66 citations

Blood and brain ethanol concentrations during absorption and distribution in long-sleep and short-sleep mice

1989 • 66 citations

Ethanol preference and behavioral tolerance in mice: Biochemical and neurophysiological mechanisms.

1973 • 66 citations

Interrelationships of alcohol consumption, actions of alcohol, and biochemical traits

1980 • 66 citations

Selective breeding of rats for differences in reactivity to alcohol. An approach to an animal model of alcoholism. II. Behavioral measures.

1977 • 65 citations

Differential concentration-response curves for oral ethanol self-administration in C57BL/6J and BALB/cJ mice

1987 • 65 citations

Reexamination of the relationship between alcohol preference and brain monoamines in inbred strains of mice including senescence-accelerated mice

1987 • 64 citations

Genetic selection of mouse lines sensitive (cold) and resistant (hot) to acute ethanol hypothermia.

1987 • 63 citations

Memory deficits subsequent to chronic consumption of alcohol in mice: An analysis based on spontaneous alternation behavior

1985 • 63 citations

Differential effects of ethanol and pentobarbital on sleep time in C57BL and BALB mice.

1974 • 62 citations

Ethanol-induced hypothermia in mice: Influence of genotype on development of tolerance

1978 • 61 citations

Differential effects of long-chain alcohols in long- and short-sleep mice

1983 • 60 citations

Genetic regulation of dihydropyridine-sensitive calcium channels in brain may determine susceptibility to physical dependence on alcohol

1990 • 60 citations

BEHAVIORAL AND PHYSIOLOGICAL DIFFERENCES AMONG RAT STRAINS SPECIALLY SELECTED FOR THEIR ALCOHOL CONSUMPTION

1972 • 59 citations

Alcohol withdrawal reactions and reserpine effects in inbred strains of mice

1974 • 58 citations

Genetic differences in the establishment of ethanol as a reinforcer

1986 • 58 citations

Persistence of tolerance to a single dose of ethanol in the selectively-bred alcohol-preferring P rat

1987 • 58 citations

Ethanol and nitrous oxide produce withdrawal-induced convulsions by similar mechanisms in mice

1987 • 57 citations

Stimulant and depressant properties of sedative-hypnotics in mice selectively bred for differential sensitivity to ethanol

1983 • 57 citations

Nicotine response and nicotinic receptors in long-sleep and short-sleep mice

1987 • 56 citations

Behavior of alcohol-preferring AA and alcohol-avoiding ANA rat lines in tests of anxiety and aggression

1990 • 56 citations

Age and strain differences in the rate of development of functional tolerance to ethanol by mice

1979 • 55 citations

Genetic approaches to studying drug abuse: Correlates of drug self-administration

1990 • 55 citations

Genetic influences on brain growth restriction induced by development exposure to alcohol.

1989 • 54 citations

Alcohol-induced conditioned aversion: Genotypic specificity in mice (Mus musculus).

1975 • 54 citations

Differential effects of pentobarbital and ethanol in mice

1976 • 53 citations

Ethanol intoxication as function of genotype dependent responses in three inbred mice strains

1982 • 53 citations

Further Characterization of LSXSS Recombinant Inbred Strains of Mice: Activating and Hypothermic Effects of Ethanol

1990 • 53 citations

Environmental variables differentially affect ethanol-stimulated activity in selectively bred mouse lines

1988 • 53 citations

Early experience and the consumption of alcohol by adult C57BL/6J mice

1989 • 53 citations

Genetic aspects of alcoholism

1986 • 52 citations

Alcohol withdrawal reactions in mouse strains selectively bred for long or short sleep times

1975 • 51 citations

Mouse strain differences in operant self-administration of ethanol

1987 • 51 citations

Oral ethanol reinforced behavior in inbred mice

1986 • 50 citations

Effects of gamma-butyrolactone, amphetamine, and haloperidol in mice differing in sensitivity to alcohol

1980 • 50 citations

Genetic Correlation of Ethanol‐induced Ataxia and Cerebellar Purkinje Neuron Depression among Inbred Strains and Selected Lines of Rats

1987 • 50 citations

Rats learning to work for alcohol

1974 • 50 citations

Molecular associations of alcohol-seeking behavior in rat lines selectively bred for high and low voluntary ethanol drinking.

1991 • 49 citations

Build-up and release from proactive interference during chronic ethanol consumption in mice: A behavioral and neuroanatomical study

1987 • 49 citations

Motor impairment, narcosis and hypothermia by ethanol: Separate genetic mechanisms

1984 • 49 citations

Effects of intravenous ethanol and of 4-methylpyrazole on alcohol drinking in alcohol-preferring rats

1982 • 49 citations

Genetic influences on the rate of development of ethanol tolerance and the ethanol physical withdrawal syndrome in mice

1979 • 48 citations

Development of central nervous system sensitivity to ethanol and pentobarbital in short- and long-sleep mice.

1990 • 48 citations

Circadian drinking rhythms and blood alcohol levels in two rat lines developed for their alcohol consumption

1986 • 48 citations

Alcohol-deprivation effect in rats genetically selected for their ethanol preference

1979 • 48 citations

Heritability of Alcohol Preference in Laboratory Mice and Rats

1970 • 48 citations

Factors involved in ethanol narcosis: Analysis in mice of three inbred strains

1973 • 48 citations

ANAESTHETIC REQUIREMENT IN MICE SELECTIVELY BRED FOR DIFFERENCES IN ETHANOL SENSITIVITY

1981 • 47 citations

Intoxicating effects of three aliphatic alcohols and barbital on two rat strains genetically selected for their ethanol intake

1978 • 47 citations

Sensitivity and tolerance to ethanol-induced hypothermia in genetically selected mice.

1989 • 47 citations

The effect of halothane on mice selectively bred for differential sensitivity to alcohol

1980 • 47 citations

An inborn alcohol tolerance in alcohol-preferring rats. The lack of relationship between tolerance to ethanol and the brain microsomal (Na+K+) ATPase activity

1977 • 47 citations

Motor activity and alcohol: Genetic analysis in the mouse

1976 • 46 citations

Prenatal ethanol exposure in C57 mice: Effects on pregnancy and offspring development

1988 • 46 citations

Selective breeding of rats for differences in reactivity to alcohol. An approach to an animal model of alcoholism. I. General procedures.

1976 • 46 citations

On the relationship between deficiency of B vitamins and alcohol intake in rats.

1951 • 46 citations

Ethanol and barbiturate withdrawal convulsions are extensively codetermined in mice

1988 • 45 citations

[Genetic aspects of alcoholism].

1989 • 45 citations

The Role of Genetics in Substance Abuse

1985 • 45 citations

Adrenal glucocorticoids as a required factor in the development of ethanol withdrawal seizures in mice

1974 • 45 citations

Alcohol consumption and sensory threshold differences between C57BL/6J and DBA/2J mice

1978 • 45 citations

Ethanol Teratogenesis in Selectively Bred Long‐Sleep and Short‐Sleep Mice: A Comparison to Inbred C57BL/6J Mice

1989 • 45 citations

Initial sensitivity and tolerance to ethanol in mice: correlations among open field activity, hypothermia, and loss of righting reflex

1981 • 44 citations

Adrenocortical function in mice selectively bred for different sensitivity to ethanol

1976 • 44 citations

Genetics of Alcoholism and Alcohol Actions

1984 • 44 citations

Genetic Differences in the Susceptibility to Acute Ethanol Intoxication in Selected Rat Strains

1977 • 43 citations

Rat strain differences in ethanol self-administration and taste aversion learning

1987 • 43 citations

Neurochemical correlates of alcohol preference in inbred strains of mice

1975 • 43 citations

Neurotensin and Ethanol Interactions on Hypothermia and Locomotor Activity in LS and SS Mice

1989 • 43 citations

Fetal Alcohol Syndrome in Twin Pregnancy

1985 • 42 citations

Circadian and Genetic Effects on Ethanol Elimination in LS and SS Mice

1982 • 42 citations

Response variability of ethanol-induced locomotor activation in mice

1988 • 42 citations

Mediation of myoclonic seizures by dopamine and clonic seizures by acetylcholine and gaba

1977 • 42 citations

Cocaine produces locomotor stimulation in SS but not LS mice: Relationship to dopaminergic function

1990 • 41 citations

Ethanol and diazepam withdrawal convulsions are extensively codetermined in WSP and WSR mice

1989 • 41 citations

On the Relationship Between Deficiency of B Vitamins and Alcohol Intake in Rats

1951 • 41 citations

Lack of alcohol-deprivation effect in AA rats

1988 • 41 citations

Ethanol self-administration in ALKO rats: I. Effects of selection and concentration

1989 • 41 citations

Nonlinear Pharmacokinetics of Ethanol Elimination in Long Sleep and Short Sleep Mice

1983 • 41 citations

Genetics and ethanol tolerance

1979 • 40 citations

Pharmacogenetic tools in the study of drug tolerance and dependence.

1980 • 40 citations

Alcohol selection by strains of rats selectively bred for behavior.

1979 • 40 citations

Fixed-ratio schedules of oral ethanol self-administration in inbred mouse strains

1988 • 40 citations

Sensitivity and tolerance to ethanol in mice bred to be genetically prone or resistant to ethanol withdrawal seizures.

1986 • 39 citations

Social Modification of Alcohol Consumption in Inbred Mice

1975 • 39 citations

Ethanol Clearance in Nine Inbred Rat Strains

1984 • 39 citations

Fetal alcohol effects in long- and short-sleep mice: Activity, passive avoidance, and in utero ethanol levels

1987 • 38 citations

Effects of pentobarbital in mice selected for differential sensitivity to ethanol

1982 • 38 citations

Correlation between the enhancement of flunitrazepam binding by GABA and seizure susceptibility in mice

1987 • 38 citations

Intoxicating effects of lorazepam and barbital in rat lines selected for differential sensitivity to ethanol

1987 • 38 citations

SELECTIVE BREEDING OF RATS FOR DIFFERENCES IN REACTIVITY TO ALCOHOL: AN APPROACH TO AN ANIMAL MODEL OF ALCOHOLISM

1977 • 38 citations

ETHANOL CONSUMPTION AND PREFERENCE IN MICE: A GENETIC ANALYSIS

1972 • 38 citations

Roots of Behavior. Genetics, Instinct, and Socialization in Animal Behavior

1963 • 37 citations

Ethanol sleep times and hepatic alcohol and aldehyde dehydrogenase activities in mice

1972 • 37 citations

The differential transplacental effects of ethanol in four mouse strains.

1980 • 37 citations

Activating and anesthetic effects of general depressants

1978 • 37 citations

Failure of Ro 15-4513 to antagonize ethanol in rat lines selected for differential sensitivity to ethanol and in wistar rats

1988 • 36 citations

Ethanol Differentially Regulates Proadrenocorticotropin/Endorphin Production and Corticosterone Secretion in LS and SS Lines of Mice*

1989 • 36 citations

Behavioral and physiological measures for studying ethanol dependence in mice

1981 • 36 citations

Sensitivity to ethanol in female mice: Effects of ovariectomy and strain

1985 • 35 citations

Salsolinol differentially affects mice selected for sensitivity to alcohol

1976 • 35 citations

Thiopental, phenobarbital, and chlordiazepoxide induce the same differences in narcotic reaction as ethanol in long-sleep and short-sleep selectively-bred mice

1986 • 34 citations

Voluntary consumption of ethanol in WSP, WSC and WSR selectively bred mouse lines

1988 • 34 citations

ALCOHOL METABOLISM OF INBRED STRAINS OF RATS WITH ALCOHOL PREFERENCE AND NONPREFERENCE

1977 • 34 citations

Mapping of a putative genetic locus determining ethanol intake in the mouse

1987 • 34 citations

Differences in the hypothermic response to ethanol in rats selectively bred for oral ethanol preference and nonpreference

1992 • 33 citations

Ethanol dependence in mice: Direct and correlated responses to ten generations of selective breeding

1984 • 33 citations

Alcohol intoxication and withdrawal in inbred strains of mice: Behavioral and endocrine studies

1979 • 33 citations

The ethanol stimulus in rats with differing ethanol preferences

1981 • 33 citations

Demonstration of lever pressing for oral ethanol by rats with no prior training or ethanol experience

1989 • 33 citations

Three heritable responses to alcohol in a heterogeneous randomly mated mouse strain. Inferences for humans.

1977 • 32 citations

Apomorphine effects on behavioral response to ethanol in mice selectively bred for differential sensitivity to ethanol

1984 • 32 citations

Rapidly developing functional tolerance to ethanol is accompanied by increased erythrocyte cholesterol in mice.

1982 • 32 citations

Audiogenic seizures in mice whose parents drank alcohol.

1976 • 32 citations

Specific ethanol withdrawal seizures in genetically selected mice

1984 • 32 citations

Long term reduction of male agonistic behavior in mice following early exposure to ethanol

1977 • 31 citations

Ethanol consumption: Selective breeding in mice

1981 • 31 citations

Increased sensitivity to chronic ethanol in isolated mice

1976 • 30 citations

Comparison of neurotensin levels, receptors and actions in LS/Ibg and SS/Ibg mice

1989 • 30 citations

Effect of alcohol on behaviorål and autonomic thermoregulation in mice

1986 • 30 citations

GENETIC DIFFERENCES IN THE EFFECTS OF VOLUNTARY ETHANOL CONSUMPTION ON BRAIN MONOAMINE LEVELS IN INBRED STRAINS OF MICE, C57BL/6J, C3H/He AND DBA/2Cr

1989 • 30 citations

A Developmental Study of Ethanol Effect on Behavior and Physical Development in Mice

1977 • 30 citations

The Relationship between Ethanol‐Induced Locomotor Activation and Narcosis in Long‐Sleep and Short‐Sleep Mice

1984 • 30 citations

Ethanol self-administration in ALKO rats: II. Effects of selection and fixed-ratio size

1989 • 30 citations

Ethanol differentially enhances adrenocortical response in LS and SS mice

1988 • 29 citations

Relationship between initial sensitivity, acute tolerance and chronic tolerance to ethanol in a heterogeneous population of Swiss mice

1989 • 29 citations

Effect of alpha-methyl-p-tyrosine on dose-dependent mouse strain differences in locomotor activity after ethanol.

1980 • 29 citations

Hyperbaric ethanol antagonism in mice: Studies on oxygen, nitrogen, strain and sex

1982 • 29 citations

Behavioral desensitization to nicotine is enhanced differentially by ethanol in long-sleep and short-sleep mice

1989 • 28 citations

Strain-specific effects of ethanol on open field activity in inbred mice.

1980 • 28 citations

Ethanol teratogenesis in mice selected for differences in alcohol sensitivity

1988 • 28 citations

Corticotropin‐Releasing Factor Is Altered in Brains of Animals with High Preference for Ethanol

1990 • 28 citations

Ethanol selection by inbred mice. Mode of inheritance and the effect of age on the genetic system.

1978 • 28 citations

Locomotor stimulant and intoxicant properties of methanol, ethanol, tertiary butanol and pentobarbital in Long-Sleep and Short-Sleep mice.

1983 • 28 citations

Alcohol intake in selected lines of mice: Importance of sex and genotype.

1979 • 28 citations

Differences in GABA activity between ethanol withdrawal seizure prone and resistant mice

1988 • 28 citations

The effects of ethanol on exploration in DBA/2 and C57B1/6 mice

1987 • 27 citations

Concentration‐Dependent Effects of Ethanol in Long‐Sleep and Short‐Sleep Mice

1983 • 27 citations

Demonstration of a threshold concentration for ethanol at the time of regaining the righting response in long-sleep and short-sleep mice.

1987 • 27 citations

The effects of ethanol and Ro 15–4513 on elevated plus-maze and rotarod performance in long-sleep and short-sleep mice

1989 • 27 citations

Effects if ethanol on behaviour of aggressive mice from two different strains: A comparison of simple and complex behavioural assessments

1983 • 27 citations

Genetic Tools in the Study of Drug Self‐administration

1988 • 27 citations

Sensitivity of inbred and selectively bred mice to ethanol

1987 • 26 citations

Alcohol and morphine induced hypothermia in mice selected for sensitivity to ethanol

1982 • 26 citations

Decreased sensitivity to nicotine-induced seizures as a consequence of nicotine pretreatment in long-sleep and short-sleep mice

1988 • 26 citations

Endocrine and Autonomic Studies in Mice Selectively Bred for Different Sensitivity to Ethanol

1977 • 26 citations

The Role of Arginine Vasopressin in Alcohol Tolerance

1990 • 26 citations

Genetic differences in anticonvulsant sensitivity in mouse lines selectively bred for ethanol withdrawal severity.

1986 • 26 citations

Lipid solubility is correlated with hypnotic and hypothermic responses of long-sleep (LS) and short-sleep (SS) mice to various depressant drugs.

1983 • 26 citations

Arginine vasopressin deficient Brattleboro rats fail to develop tolerance to the hypothermic effects of ethanol

1982 • 25 citations

Differential Modulation by the Stress Axis of Ethanol Withdrawal Seizure Expression in WSP and WSR Mice

1991 • 25 citations

Evidence that the selectively bred long- and short-sleep mouse lines display common narcotic reactions to many depressants

1985 • 25 citations

Use of genetic to test the potential role of serotonin in alcohol preference

1975 • 25 citations

The use of strain rank orders in assessing equivalence of techniques

1968 • 25 citations

Genetic Analysis of Ethanol Preference in Rats Selected for Emotional Reactivity

1968 • 25 citations

Moderate prenatal ethanol exposure interacts with strain in affecting brain development in and mice

1985 • 25 citations

Differential Reinforcement and Diurnal Rhythms of Lever Pressing for Ethanol in AA and Wistar Rats

1990 • 25 citations

Genetic influences on the central nervous system depressant and membrane-disordering actions of ethanol and sodium valproate.

1984 • 25 citations

Behavioral interactions of ethanol and methylxanthines

1987 • 24 citations

Behavioral effects of salsolinol and ethanol on mice selected for sensitivity to alcohol-induced sleep time

1977 • 24 citations

Selective breeding in mice for severity of the ethanol withdrawal syndrome.

1982 • 24 citations

Behavioural sensitivity to pia in selectively bred mice is related to a number of A1 adenosine receptors but not to cyclic AMP accumulation in brain slices

1985 • 24 citations

EFFECT OF PRENATAL ALCOHOL EXPOSURE ON NEONATAL SLEEP-WAKE BEHAVIOUR AND ADULT ALCOHOL CONSUMPTION IN THE AA AND ANA RAT LINES

1987 • 24 citations

The grid test: A measure of alcohol- and barbiturate-induced behavioral impairment in mice

1975 • 24 citations

Brain aldehyde dehydrogenase activity in rat strains with high and low ethanol preferences

1981 • 24 citations

Differential Regulation of Anterior Pituitary Corticotrope Function is Observed in Vivo but not in Vitro in Two Lines of Ethanol‐Sensitive Mice

1990 • 23 citations

Relating TIQ's, opiates, and ethanol.

1982 • 23 citations

Ethanol-induced adrenomedullary catecholamine secretion in LS/Ibg and SS/Ibg mice.

1986 • 23 citations

Effects of initial tolerance on acquired tolerance to alcohol in two selectively bred rat strains

1977 • 23 citations

Temperature affects ethanol lethality in C57BL/6, 129, LS and SS mice

1989 • 23 citations

The effects of high dose sporadic (binge) alcohol intake in mice

1984 • 23 citations

Handling induced convulsions in twenty inbred strains of mice.

1980 • 23 citations

Effect of prenatal ethanol exposure on activity and shuttle avoidance behavior in adult C57 mice.

1985 • 23 citations

Consumption of intoxicating beverages by rats and mice exhibiting high and low preferences for ethanol

1981 • 23 citations

Vasopressin and ethanol preference. I. Effects of vasopressin and the fragment DGAVP on altered ethanol preference in Brattleboro diabetes insipidus rats

1985 • 22 citations

Mitogens as Probes of Lymphocyte Heterogeneity in Anuran Amphibians

1975 • 22 citations

Studies on Tolerance Development in Inbred and Heterogeneous Stock National Institutes of Health Rats

1984 • 22 citations

Acute ethanol effects on blood pH, PCO2, and PO2 in LS and SS mice

1982 • 22 citations

Body temperature differentially affects ethanol sensitivity in both inbred strains and selected lines of mice.

1990 • 22 citations

Heredity and alcohol-induced brain anomalies: Effects of alcohol on anomalous prenatal development of the corpus callosum and anterior commissure in BALBc and C57BL6 mice

1987 • 21 citations

Relationship between Acute Ethanol‐related Responses in Long‐Sleep and Short‐Sleep Mice

1987 • 21 citations

Alcohol Dependence and Withdrawal: A Genetic Animal Model

1990 • 21 citations

Genetic components of ethanol responses

1990 • 21 citations

Differential response to flurazepam in long-sleep and short-sleep mice

1988 • 21 citations

Sedative-hypnotic anomalies related to dose of pentobarbital in long-Sleep and short-sleep selectively-bred mice

1986 • 21 citations

Withdrawal-like signs induced by a single administration of ethanol in mice that differ in ethanol sensitivity

1980 • 20 citations

Genetic brain polypeptide variants in inbred mice and in mouse strains with high and low sensitivity to alcohol

1985 • 20 citations

Locomotor activity response to chronic ethanol treatment in selectively bred FAST and SLOW mice.

1991 • 20 citations

Antagonism of Ethanol Narcosis in Mice by Hyperbaric Pressures of 4–8 Atmospheres

1980 • 20 citations

Effect of neonatal clomipramine treatment on adult alcohol drinking in the AA and ANA rat lines

1986 • 19 citations

A dopaminergic basis for the effects of amphetamine on a mouse “preadolescent hyperkinetic” model

1977 • 19 citations

Temperature dependence of ethanol depression in C57BL/6 and BALB/c mice

1984 • 19 citations

A comparison of ethanol absorption and narcosis in Long- and Short-Sleep mice following intraperitoneal or intragastric ethanol administration

1985 • 19 citations

Task-dependent genetic influences on behavioral response of mice (Mus musculus) to acetaldehyde.

1978 • 19 citations

Tolerance to ethanol-induced impairment of water escape in rats bred for ethanol sensitivity

1980 • 19 citations

Genetic analysis of tolerance to ethanol hypothermia in recombinant inbred mice: Effect of desglycinamide(9)-Arginine(8)-vasopressin

1980 • 19 citations

Factors involved in the differential response to ethanol, barbital and pentobarbital in rats selectively bred for ethanol sensitivity

1982 • 18 citations

Ethanol consumption and hepatic enzyme activity

1979 • 18 citations

Concentrations of free amino acids in brains of mice of different strains during the physical syndrome of withdrawal from alcohol.

1977 • 18 citations

Genetic differences in tolerance to ethanol: A study in UChA and UChB rats

1981 • 18 citations

Membrane fatty acid changes and ethanol tolerance in rat and mouse

1984 • 17 citations

Long-term effects of early ethanol on predatory behavior in inbred mice

1976 • 17 citations

Responses to ethanol challenge in long- and short-sleep mice prenatally exposed to alcohol

1990 • 17 citations

Differential tolerance to pentobarbital in rats bred for differences in alcohol sensitivity

1978 • 17 citations

Ethanol-induced analgesia in rats selectivity bred for ethanol sensitivity

1980 • 17 citations

Differential pharmacological responses to ethanol, pentobarbital and morphine in rats selectively bred for ethanol sensitivity

1983 • 16 citations

Plus-maze behavior and susceptibility to 3-mercaptopropionate-induced seizures in rat lines selected for high and low alcohol sensitivity

1990 • 16 citations

Selective Breeding for a Multivariate Index of Ethanol Dependence in Mice: Results from the First Five Generations

1983 • 16 citations

Open-field emotional reactivity and alcohol intake in rats

1982 • 16 citations

Alcohol absorption rate affects hypothermic response in mice: Evidence for rapid tolerance

1989 • 16 citations

Response to selection for sensitivity to ethanol hypothermia: Genetic analyses

1990 • 16 citations

Fertility and offspring survival in mice selected for different sensitivities to alcohol

1977 • 16 citations

Genetically determined differences in ethanol sensitivity influenced by body temperature during intoxication

1988 • 16 citations

Differential CNS sensitivity to PIA and theophylline in long-sleep and short-sleep mice

1985 • 16 citations

Hippocampal rhythmic slow activity in rat lines selected for differences in ethanol-induced motor impairment

1988 • 15 citations

Ethanol interoceptive cue and sleep-time duration in HAS and LAS selectively bred rats

1990 • 15 citations

A simplified triple-test cross analysis of alcohol preference in the rat

1981 • 15 citations

Differential effects of ethanol concentration on blood pH, PCO2 and PO2 in LS and SS Mice☆

1983 • 14 citations

Tolerance and cross-tolerance to morphine and ethanol in mice selectively bred for differential sensitivity to ethanol.

1983 • 14 citations

Rats bred for ethanol sensitivity: Impairment of swimming by ethanol and pentobarbital

1979 • 14 citations

Isolate housing alters ethanol sensitivity in long-sleep and short-sleep mice

1990 • 14 citations

Alcohol Imbibition and Behavior: A Comparative Genetic Approach

1975 • 14 citations

Persistence of tolerance in the P line of alcohol-preferring rats does not require performance while intoxicated

1990 • 14 citations

Strain differences in circadian drinking behaviors of ethanol and water in rats.

1987 • 14 citations

Differential response to ethanol, pentobarbital and morphine in mice selectively bred for ethanol sensitivity

1984 • 14 citations

Paradoxical effects of d‐amphetamine upon seizure susceptibility in 2 selectively bred lines of mice

1980 • 14 citations

A Genetic Analysis of Ethanol, Pentobarbital, and Methyprylon Sleep‐Time Response

1984 • 14 citations

Dissociation between the anticonvulsant action of alcohol and its depressant action in mice of different genotypes

1978 • 13 citations

Effects of ethanol on aggression in three inbred strains of mice

1987 • 13 citations

Ethanol-induced conditioned taste aversions in mice that differ in neural sensitivity to ethanol.

1982 • 13 citations

Circadian and genetic influences on tissue sensitivity and sleep time to ethanol in LS and SS mice

1983 • 13 citations

Effect of alcohols and other hypnotics in mice selected for differential sensitivity to hypothermic actions of ethanol.

1991 • 13 citations

Initial Sensitivity of Rat Inbred Strains to Acute Alcohol

1984 • 13 citations

Quantification of Physiological and Behavioral Measures of Alcohol Withdrawal in Long‐Sleep and Short‐Sleep Mice

1986 • 13 citations

Central Mechanisms of Ethanol-Induced Adrenocortical Response in Selectively Bred Lines of Mice

1987 • 13 citations

Thyroid status during postnatal maturation of the brain in mice genetically bred for differences in ethanol sensitivity.

1986 • 13 citations

Use of chromosomally mapped and identified mouse brain proteins for behavioral genetic analysis of alcoholism

1986 • 13 citations

Alcohol-preferring and alcohol-avoiding C57BL mice

1972 • 13 citations

Behavioral effects of ethanol and salsolinol in mice selectively bred for acute sensitivity to ethanol☆

1984 • 12 citations

Correlation of Purkinje Neuron Depression and Hypnotic Effects of Ethanol in Inbred Strains of Rats

1985 • 12 citations

Sensitivity to Ethanol Hypnosis and Modulation of Chloride Channels Does Not Cosegregate with Pentobarbital Sensitivity in HS Mice

1989 • 12 citations

Effect of ethyl alcohol on thermoregulation in mice following the induction of hypothermia or hyperthermia

1988 • 12 citations

Generality of differential sensitivity to alcohol in selectively bred rats

1977 • 12 citations

Convulsant properties of GABA antagonists and anticonvulsant properties of ethanol in selectively bred Long- and Short-Sleep mice

1989 • 12 citations

Differences in the sleep-wake patterns of the AA and ANA rat lines developed for high and low alcohol intake

1986 • 12 citations

Schedule induced ethanol polydipsia in psychogenetically selected lines of rats

1981 • 12 citations

Genetic models of alcohol dependence.

1987 • 11 citations

Selective Breeding of Rats for Differences in Reactivity to Alcohol: An Approach to an Animal Model of Alcoholism. III. Some Physical and Behavioral Measures

1977 • 11 citations

Lack of association between preference for and dependence on ethanol

1982 • 11 citations

Morphine withdrawal in mice selectively bred for differential sensitivity to ethanol

1982 • 11 citations

Avoidance behavior in rats selectively bred for differential alcohol sensitivity

1980 • 10 citations

Effect of neurotransmitter-selective drugs in mice selected for differential sensitivity to the hypothermic actions of ethanol.

1991 • 10 citations

Differential neurosensitivity to three alcohols and phenobarbital in C57BL/6J and DBA/2J mice

1982 • 10 citations

Hypnotic susceptibility to various depressants in rats selected for differential ethanol sensitivity

1979 • 10 citations

Inheritance of behaviour towards alcohol in normal and motivated choice situations in mice

1971 • 10 citations

Individual Differences in Substance Abuse

1985 • 10 citations

Appetite for alcohol: influence of genetics and early experience.

1985 • 10 citations

Genetic Differences in the Effect of Ethanol on Plasma Corticosterone and Nonesterified Fatty Acid in Rats

1984 • 10 citations

Roots of behavior : genetics, instinct, and socialization in animal behavior

1962 • 10 citations

Ethanol sensitivity and membrane lipid composition in three strains of mouse

1984 • 10 citations

An experimental model of self-intoxication in C57 mice

1985 • 10 citations

Genetic influences on alcohol consumption and actions of alcohol.

1981 • 10 citations

Dose-response effects of alcohol upon rat strains bred for differences in reactivity to alcohol

1977 • 10 citations

Vasopressin and ethanol preference. II. Altered preference in two strains of diabetes insipidus rats and nephrogenic diabetes insipidus mice

1985 • 10 citations

Dissociation of Components of Ethanol Intoxication and Tolerance

1982 • 9 citations

Temperature modulates ethanol sensitivity in mice: Generality across strain and sex

1985 • 9 citations

The genetics of alcohol preference in the female rat confirmed by a full triple-test cross

1983 • 9 citations

Effect of different treatment regimens with ethanol and p-chlorophenylalanine on tolerance development in UChA and UChB rats

1988 • 8 citations

Indomethacin antagonism of ethanol-induced sleep time: Sex and genotypic factors

1985 • 8 citations

Differential neurohumoral modulation of myoclonic and clonic seizures.

1978 • 8 citations

The Influence of Catecholamine Systems and Thyroid Function on the Actions of Ethanol in Long‐Sleep (LS) and Short‐Sleep (SS) Micea

1987 • 8 citations

Modification of ethanol effects by bicuculline: genotype-dependent responses and inheritance

1989 • 8 citations

Alcohol Withdrawal Convulsions in Genetically Different Populations of Mice

1975 • 8 citations

Effect of Ethanol on Motor Performance and Hippocampal Population Spikes in Some Standard and Selectively Outbred Rat Strains

1987 • 8 citations

Genetic influence on increased seizure susceptibility in pregnancy

1986 • 7 citations

Effect of chronic ivermectin treatment on GABA receptor function in ethanol withdrawal-seizure prone and resistant mice.

1990 • 7 citations

The influence of infantile handling, age and strain on alcohol selection in mice

1985 • 7 citations

The relative contribution of pre- and neonatal ethanol administration to changes in mice behavior.

1979 • 7 citations

Ethanol-induced grooming in mice selectively bred for differential sensitivity to ethanol

1985 • 6 citations

Comparison of the excitatory and anaesthetic effects of ethanol in C57BL/6 and BALB/c mice; relation to blood ethanol concentration.

1978 • 6 citations

Sensitivity to the Anticonvulsant Effects of Ethanol and Pentobarbital in Mouse Lines Genetically Selected for Ethanol Sensitivity

1989 • 6 citations

Task-dependent ethanol effects on escape in rats bred for ethanol sensitivity

1981 • 6 citations

ETHANOL PREFERENCE IN HOMOZYGOUS DIABETES INSIPIDUS (BRATTLEBORO) RATS: EFFECT OF VASOPRESSIN FRAGMENTS*

1982 • 6 citations

Genetic analysis of sensitivity to ethanol-induced depression of motor activity and impairment of swimming in rats

1983 • 6 citations

Patterns of convulsive susceptibility in the long-sleep and short-sleep selected mouse lines

1989 • 5 citations

Alcohol-preferring (AA) and alcohol-avoiding (ANA) lines of rats after introgression of alien genes.

1987 • 5 citations

Ethanol-induced hypothermia and hyperglycemia in genetically obese mice

1989 • 5 citations

Ethanol-induced flavor aversions in mice. A behavior-genetic analysis.

1980 • 5 citations

Developmental and genotypic effects on pituitary-adrenal function and alcohol tolerance in mice

1979 • 4 citations

Genotypic-dependent amphetamine effects in rats bred for differences in alcohol sensitivity

1979 • 4 citations

Self-administration of ethanol by genetically heterogeneous mice (RU:NCS): Relationship to sensitivity and tolerance

1983 • 4 citations

Genetic and ethanol‐related differences in maternal behavior and offspring viability in mice

1979 • 3 citations

More on the heritability of alcohol preference in laboratory mice and rats

1983 • 3 citations

Adrenal hormones and ethanol ingestion in C57BL/Crgl and C3H/Crgl/2 mice

1981 • 3 citations

Effects of pyrazole on the voluntary consumption of ethanol, water and solid food in UChA and UChB rats

1988 • 3 citations

Ethanol preference in mice following acute or chronic ethanol administration

1984 • 3 citations

Vasopressin and ethanol preference

1986 • 3 citations

Multivariate Diallel Analysis of Ethanol Withdrawal Symptoms in Mice

1988 • 2 citations

Genetic effects on various measures of ethanol dependence in mice: A diallel analysis

1984 • 2 citations

Genetic influences on acquisition of tolerance to alcohol

1985 • 2 citations

Abomasal function following injections of elfazepam and 9-aza-cannabinol

1979 • 2 citations

Tolerance development in UChA and UChB rats by ethanol inhalation

1989 • 2 citations

Individual Versus Group Learning: Developmental and Social Differences in Two Selected Mouse Lines

1985 • 1 citations

Age dependent changes in aversive responses of mice to ethanol and their correlation with life duration

1984 • 1 citations

Effects of intraperitoneal ethanol injections on the locomotor activity of five inbred strains of mice. Abstr.

1975 • 1 citations