The role of epidermal growth factor in normal and neoplastic growth of mouse mammary epithelial cells

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Isolation of a Mouse Submaxillary Gland Protein Accelerating Incisor Eruption and Eyelid Opening in the New-born Animal

1962 • 2,192 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

The Mouse in Biomedical Research

1983 • 1,072 citations

Multiple hormone interactions in the developmental biology of the mammary gland.

1980 • 866 citations

The Function and Mechanism of Promoters of Carcinogenesis

1973 • 759 citations

The Primary Structure of Epidermal Growth Factor

1972 • 533 citations

EPIDERMAL-GROWTH-FACTOR RECEPTORS AND OESTROGEN RECEPTORS IN HUMAN BREAST CANCER

1985 • 496 citations

Biologically active polypeptides in submandibular glands.

1980 • 474 citations

Structure of a Mouse Submaxillary Messenger RNA Encoding Epidermal Growth Factor and Seven Related Proteins

1983 • 448 citations

Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: amino acid sequence homology with epidermal growth factor.

1983 • 403 citations

Epidermal Growth Factor: Effects of Androgens and Adrenergic Agents

1974 • 393 citations

POLYPEPTIDE GROWTH FACTORS

1984 • 381 citations

Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts.

1978 • 358 citations

Mammary Neoplasia in Mice

1973 • 332 citations

The Nude Mouse in Experimental and Clinical Research

1979 • 306 citations

Induction of Epidermal Growth Factor-Related Polypeptides by 17β-Estradiol in MCF-7 Human Breast Cancer Cells

1986 • 296 citations

Hormonal effects on intracellular and secreted casein in cultures of mouse mammary epithelial cells on floating collagen membranes.

1977 • 292 citations

Endocrine Control of Mammary-Gland Development and Function in the C3H/He Crgl Mouse<xref ref-type="fn" rid="FN1">2</xref>

1958 • 281 citations

Regulation of Cell Proliferation by Epidermal Growth Factor

1983 • 235 citations

A Physiological Role of Epidermal Growth Factor in Male Reproductive Function

1986 • 228 citations

Presence of transforming growth factors in human breast cancer cells.

1984 • 222 citations

Sulfate and Nitrate Concentrations from a South Greenland Ice Core

1986 • 219 citations

The Nude mouse in experimental and clinical research

1978 • 205 citations

Characterization of epidermal growth factor receptor and action on human breast cancer cells in culture.

1984 • 201 citations

Alfred P. Sloan Jr. Award.The epidermal growth factor (EGF)

1983 • 198 citations

Growth factors: The epidermal growth factor receptor gene and its product

1984 • 187 citations

Recent Studies on the Chemistry and Biology of Epidermal Growth Factor

1974 • 169 citations

Epidermal growth factor requirement for development of cultured mammary gland

1980 • 165 citations

Epidermal growth factor: Biological activity requires persistent occupation of high-affinity cell surface receptors

1978 • 162 citations

The Gestational Pattern of Estradiol, Testosterone and Progesterone Secretion in Selected Strains of Mice

1979 • 155 citations

Growth Factor- and Cyclic Nucleotide-Induced Proliferation of Normal and Malignant Mammary Epithelial Cells in Primary Culture*

1980 • 145 citations

Responses of Mammary Cells to Hormones

1976 • 133 citations

The mouse submandibular gland: an exocrine organ for growth factors.

1980 • 132 citations

The role of epithelial growth factor in mammary gland development in vitro

1969 • 128 citations

Epidermal Growth Factor Stimulates Cell Proliferation and Inhibits Functional Differentiation of Mouse Mammary Epithelial Cells in Culture*

1983 • 126 citations

Evidence for the involvement of the submandibular gland epidermal growth factor in mouse mammary tumorigenesis.

1985 • 118 citations

EPIDERMAL-GROWTH-FACTOR RECEPTORS AND ESTROGEN-RECEPTORS IN HUMAN-BREAST CANCER

1985 • 114 citations

Gastrointestinal absorption of epidermal growth factor in suckling rats

1984 • 112 citations

Correlation between hormone dependency and the regulation of epidermal growth factor receptor by tumor promoters in human mammary carcinoma cells.

1986 • 98 citations

Epidermal growth factor enhancement of skin tumor induction in mice

1976 • 96 citations

Evidence for physiological function of epidermal growth factor: pregestational sialoadenectomy of mice decreases milk production and increases offspring mortality during lactation period.

1984 • 86 citations

Changes in epidermal growth factor concentrations of submandibular gland, plasma and urine of normal and sialoadenectomized female mice during various reproductive stages

1985 • 86 citations

Epidermal Growth Factor Receptor Levels in Mouse Mammary Glands in Various Physiological States*

1985 • 86 citations

The Effect of Progestins on Submaxillary Gland Epidermal Growth Factor: Demonstration of Androgenic, Synandrogenic and Antiandrogenic Actions

1975 • 81 citations

The Regulation of Cell Proliferation: Advances in the Biology and Mechanism of Action of Epidermal Growth Factor

1978 • 78 citations

Recent Studies of the Hormonal Influence in Mouse Mammary Tumorigenesis

2015 • 74 citations

Biological action of epidermal growth factor and its functional receptors in normal mammary epithelial cells.

1983 • 74 citations

Tumor promoter 12-O-tetradecanoylphorbol 13-acetate, like epidermal growth factor, stimulates cell proliferation and inhibits differentiation of mouse mammary epithelial cells in culture.

1983 • 63 citations

Growth of mouse mammary gland end buds cultured in a collagen gel matrix

1982 • 55 citations

Stimulation of mammary carcinoma cell proliferation by epithelial growth factor in vitro.

1969 • 49 citations

Cyclic AMP as a negative regulator of hormonally induced lactogenesis in mouse mammary gland organ culture.

1980 • 45 citations

Epidermal Growth Factors Enhances Viral Transformation of Granulosa Cells

1981 • 42 citations

Bifunctional Activity of Epidermal Growth Factor onα- andκ-Casein Gene Expression in Rodent Mammary Glandsin Vitro

1986 • 40 citations

Mammary tumors in the mouse.

1981 • 40 citations

Epidermal growth factor measurements in mouse plasma: method, ontogeny, and sex difference

1985 • 36 citations

Epidermal growth factor in mouse urine: non-blood origin, and increase by sialoadenectomy and T4 therapy

1985 • 35 citations

Importance of epidermal growth factor in implantation and growth of mouse mammary tumor in female nude mice.

1987 • 30 citations

Regulation of the level of epidermal growth factor by oestrogen in the submandibular gland of female mice

1986 • 25 citations