Alfred P. Sloan Jr. Award.The epidermal growth factor (EGF)

Epidermal Growth Factor

1979 • 2,964 citations

Isolation of a Mouse Submaxillary Gland Protein Accelerating Incisor Eruption and Eyelid Opening in the New-born Animal

1962 • 2,192 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

Epidermal Growth Factor and a New Derivative

1972 • 1,225 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity.

1980 • 853 citations

A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma membrane vesicles.

1982 • 788 citations

Isolation and structure of urogastrone and its relationship to epidermal growth factor

1975 • 751 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

The Primary Structure of Epidermal Growth Factor

1972 • 533 citations

Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor.

1979 • 530 citations

Human epidermal growth factor: isolation and chemical and biological properties.

1975 • 499 citations

Characterization of the binding of 125-I-labeled epidermal growth factor to human fibroblasts

1975 • 432 citations

The stimulation of epidermal proliferation by a specific protein (EGF)

1965 • 421 citations

Insulin and epidermal growth factor. Human fibroblast receptors related to deoxyribonucleic acid synthesis and amino acid uptake.

1975 • 367 citations

The Stimulation of Epidermal Keratinization by a Protein Isolated from the Submaxillary Gland of the Mouse**From the Department of Biochemistry and the Department of Pathology, Vanderbilt University School of Medicine, Nashville, Tennessee.

1963 • 310 citations

Molecular mechanism of mitogen action: Processing of receptor induced by epidermal growth factor

1978 • 271 citations

Growth and maturation factors

1983 • 269 citations

Epidermal growth factor

1974 • 236 citations

Epidermal Growth Factor

1973 • 233 citations

Affinity labeling of the protein kinase associated with the epidermal growth factor receptor in membrane vesicles from A431 cells.

1982 • 232 citations

Monoclonal antibodies against receptor for epidermal growth factor induce early and delayed effects of epidermal growth factor.

1981 • 191 citations

Epidermal Growth Factor: Identification of a New Hormone in Human Urine

1975 • 186 citations

Purification and characterization of epidermal growth factor receptor/protein kinase from normal mouse liver.

1982 • 183 citations

Epidermal growth factor stimulates the phosphorylation of synthetic tyrosine-containing peptides by A431 cell membranes.

1982 • 166 citations

Epidermal Growth Factor-Urogastrone, a Polypeptide Acquiring Hormonal Status

1980 • 156 citations

Characterization by electrophoresis of epidermal growth factor stimulated phosphorylation using A-431 membranes

1980 • 153 citations

Purified EGF receptor–kinase interacts specifically with antibodies to Rous sarcoma virus transforming protein

1981 • 130 citations

Transformation Induced by Abelson Murine Leukemia Virus Involves Production of a Polypeptide Growth Factor

1982 • 108 citations

Similarities and differences between the effects of epidermal growth factor and Rous sarcoma virus.

1981 • 108 citations

Alteration of epidermal growth factor-dependent phosphorylation during rat liver regeneration.

1982 • 96 citations

Anti-pp60src antibodies are substrates for EGF-stimulated protein kinase

1981 • 78 citations

Rapid and specific enhancement of phosphorylation of two normal rat kidney cell membrane polypeptides of Mr = 170,000 and 150,000 by epidermal growth factor in vitro.

1981 • 44 citations