Oncogenes and human breast cancer.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Mutation and Cancer: Statistical Study of Retinoblastoma

1971 • 7,335 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

Easy calculations of lod scores and genetic risks on small computers.

1984 • 1,526 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1988 • 1,440 citations

Localization of the gene for familial adenomatous polyposis on chromosome 5

1987 • 1,386 citations

Amplification of a Novel v- erb B-Related Gene in a Human Mammary Carcinoma

1985 • 1,064 citations

Von Hippel–Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma

1988 • 661 citations

Chromosome 5 allele loss in human colorectal carcinomas

1987 • 566 citations

Inheritance of human breast cancer: evidence for autosomal dominant transmission in high-risk families.

1988 • 510 citations

Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas.

1986 • 413 citations

Alterations of myc , myb , and ras ^Ha Proto-Oncogenes In Cancers Are Frequent and Show Clinical Correlation

1986 • 379 citations

Alterations to either c-erbB-2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis.

1987 • 360 citations

Tumorigenesis by mouse mammary tumor virus: Proviral activation of a cellular gene in the common integration region int-2

1984 • 356 citations

Use of cyclosporin a in establishing epstein-barr virus-transformed human lymphoblastoid cell lines

1984 • 355 citations

Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene.

1987 • 335 citations

Reduction to Homozygosity of Genes on Chromosome 11 in Human Breast Neoplasia

1987 • 329 citations

A PROSPECTIVE STUDY OF THE DEVELOPMENT OF BREAST CANCER IN 16,692 WOMEN WITH BENIGN BREAST DISEASE

1988 • 328 citations

Insertional mutagenesis of the myc locus by a LINE-1 sequence in a human breast carcinoma

1988 • 320 citations

A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells.

1985 • 320 citations

Unique allelic restriction fragments of the human Ha-ras locus in leukocyte and tumour DNAs of cancer patients

1985 • 283 citations

Report of the committee on human gene mapping by recombinant DNA techniques

1984 • 274 citations

Amplification of c- erb B-2 and Aggressive Human Breast Tumors?

1988 • 240 citations

Association of multiple copies of the c-erbB-2 oncogene with spread of breast cancer.

1987 • 214 citations

Characterization and Chromosome Assignment of the Human Homolog of int-2, a Potential Proto-Oncogene

1986 • 178 citations

Amplification of the int-2 gene in primary human breast tumors.

1988 • 172 citations

Amplification of the c-myc oncogene in one of five human breast carcinoma cell lines.

1984 • 152 citations

Amplification of the neu (c-erbB-2) Oncogene in Human Mammmary Tumors is Relatively Frequent and is Often Accompanied by Amplification of the Linked c-erbA Oncogene

1987 • 74 citations

Nuclear thyroid hormone receptors in a human breast cancer cell line.

1978 • 54 citations

Presence of an allelic EcoRI restriction fragment of the c-mos locus in leukocyte and tumor cell DNAs of breast cancer patients.

1985 • 44 citations

Response : Amplification c- erb B-2 and Aggressive Human Breast Tumors?

1988 • 41 citations

Chromosomal localization of the human oncogene <i>ERBA2</i>

1986 • 32 citations

Amplification and over-expression of the neu oncogene in human breast carcinomas.

1988 • 31 citations

A test of the role of two oncogenes in inherited predisposition to colon cancer.

1983 • 17 citations

Localization of the oncogene c‐erbA2 to human chromosome 3

1987 • 17 citations

Two adjacent mutations at position 12 activate the K-ras2 oncogene of a human mammary tumor cell line.

1987 • 14 citations

A single point mutation responsible for c-mos polymorphism in cancer patients.

1987 • 9 citations

Anonymous genomic fragment co-amplified with c-Ki-ras 2 detects frequent polymorphism (pK42)

1986 • 3 citations