Involvement of cyclic AMP in the direct inotropic action of amrinone

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Symposia of the Society for Experimental Biology.

1969 • 962 citations

Role of calcium ions in transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres.

1978 • 638 citations

Properties of Two Inward Membrane Currents in the Heart

1979 • 409 citations

Hemodynamic Assessment of Amrinone

1978 • 390 citations

A simple ultrasensitive method for the assay of cyclic AMP and cyclic GMP in tissues

1976 • 328 citations

Cyclic AMP and contractile activity in heart.

1977 • 291 citations

Influence of Caffeine and other Methylxanthines on Mechanical Properties of Isolated Mammalian Heart Muscle: EVIDENCE FOR A DUAL MECHANISM OF ACTION

1972 • 262 citations

Relationship between internal calcium and outward current in mammalian ventricular muscle; a mechanism for the control of the action potential duration?

1976 • 250 citations

Is potassium conductance of cardiac Purkinje fibres controlled by [Ca2+]i?

1975 • 233 citations

Interaction between cyclic adenosine monophosphate and cyclic gunaosine monophosphate in guinea pig ventricular myocardium.

1975 • 228 citations

Excitation-contraction coupling in cardiac muscle

1980 • 227 citations

Cardiotonic activity of amrinone--Win 40680 [5-amino-3,4'-bipyridine-6(1H)-one].

1979 • 220 citations

Amrinone: a new non-glycosidic, non-adrenergic cardiotonic agent effective in the treatment of intractable myocardial failure in man.

1979 • 215 citations

Effects of amrinone on myocardial energy metabolism and hemodynamics in patients with severe congestive heart failure due to coronary artery disease.

1980 • 212 citations

Field stimulation as a means of effecting the graded release of autonomic transmitters in isolated heart muscle.

1966 • 209 citations

Cyclic AMP and contractile activity in heart.

1977 • 195 citations

Cardiac Actions of Glucagon

1968 • 194 citations

GTP-dependent inhibition of cardiac adenylate cyclase by muscarinic cholinergic agonists

1979 • 178 citations

Slow inward current and its role mediating the chronotropic effect of epinephrine in the rabbit sinoatrfal node

1980 • 163 citations

New cardiotonic agents: A search for digitalis substitute

1978 • 159 citations

The effects of amrinone on contractility, Ca2+ uptake and cAMP in smooth muscle

1980 • 123 citations

Effects of Beta- and Alpha-Adrenoceptor Activators and Adrenergic Transmitter Releasing Agents on the Mechanical Activity of the Heart

1980 • 116 citations

Biphasic Action of Acetylcholine on Ventricular Myocardium

1965 • 100 citations

An improved assay of cyclic 3?,5?-nucleotide phosphodiesterases with QAE-Sephadex columns

1980 • 88 citations

Effects of several phosphodiesterase-inhibitors on guinea-pig myocardium

1978 • 80 citations

The effects of adrenaline and theophylline on action potential and contraction of mammalian ventricular muscle under “rested-state” and “steady-state” stimulation

1977 • 74 citations

The role of cyclic adenosine 3', 5'-monophosphate and calcium in the regulation of contractility and glycogen phosphorylase activity in guinea pig papillary muscle.

1976 • 71 citations

Correlation of cyclic AMP and cyclic GMP levels with changes in contractile force of dog ventricular myocardium during cholinergic antagonism of positive inotropic actions of histamine, glucagon, theophylline and papaverine.

1979 • 63 citations

The time course of changes in cyclic nucleotide levels during cholinergic inhibition of positive inotropic actions of isoprenaline and theophylline in the isolated canine ventricular myocardium

1980 • 51 citations

Direct vasodilator and positive inotropic actions of amrinone

1980 • 51 citations

[Evaluation of inotropically active drugs on isolated papillary muscle].

1967 • 47 citations

Calcium-dependent slow action potentials in potassium-depolarized guinea-pig ventricular myocardium enhanced by barium ions

1980 • 45 citations

Blockade of the positive inotropic actions of epinephrine and theophylline by acetylcholine.

1967 • 43 citations

Muscarinic antagonism of the effects of phosphodiesterase inhibitor (methylisobutylxanthine) in embryonic chick ventricle.

1980 • 43 citations

Effects of amrinone, a cardiotonic drug, on calcium movements in dog erythrocytes.

1980 • 37 citations

Effect of noradrenaline on an early and a late component of the myocardial contraction

1978 • 36 citations

The dependence on contraction frequency of the positive inotropic effect of dihydro-ouabain

1977 • 29 citations

The effects of amrinone on transport and cyclic AMP metabolism in toad urinary bladder.

1981 • 18 citations

Interaction of four methylxanthine compounds and norepinephrine on cardiac phosphorylase activation and cardiac contractility.

1973 • 14 citations

Correlation of cyclic AMP and cyclic GMP levels with changes in contractile force of dog ventricular myocardium during cholinergic antagonism of positive inotropic actions of histamine, glucagon, theophylline and papaverine

1979 • 14 citations

Characterization of the inotropic and biochemical properties of amrinone — A novel cardiotonic agent

1980 • 8 citations

Amrinone, isoproterenol and ouabain modification of cardiac K+ contracture

1981 • 8 citations