Growth Regulation in Vitro and the Role of Serum

The limited in vitro lifetime of human diploid cell strains

1965 • 5,595 citations

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

1963 • 2,742 citations

Isolation of a Mouse Submaxillary Gland Protein Accelerating Incisor Eruption and Eyelid Opening in the New-born Animal

1962 • 2,192 citations

A Platelet-Dependent Serum Factor That Stimulates the Proliferation of Arterial Smooth Muscle Cells In Vitro

1974 • 1,838 citations

Nutrition Needs of Mammalian Cells in Tissue Culture

1955 • 1,562 citations

Atherosclerosis and the Arterial Smooth Muscle Cell

1973 • 1,503 citations

Agar suspension culture for the selective assay of cells transformed by polyoma virus

1964 • 1,265 citations

Polyoma transformation of hamster cell clones—an investigation of genetic factors affecting cell competence

1962 • 1,234 citations

Nutrition of Animal Cells in Tissue Culture. I. Initial Studies on a Synthetic Medium.,

1950 • 1,066 citations

Do Cells Cycle?

1973 • 885 citations

The initiation of cell division in a contact‐inhibited mammalian cell line

1965 • 807 citations

Localisation of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth

1974 • 786 citations

Platelets as a source of fibroblast growth-promoting activity

1974 • 625 citations

Observations on the social behaviour of cells in tissue culture

1954 • 606 citations

Purification of a fibroblast growth factor from bovine pituitary.

1975 • 595 citations

Characteristics of an assay for Rous sarcoma virus and Rous sarcoma cells in tissue culture

1958 • 555 citations

Anchorage and growth regulation in normal and virus‐transformed cells

1968 • 547 citations

"Contact inhibition" of cell division in 3T3 cells.

1968 • 547 citations

The Primary Structure of Epidermal Growth Factor

1972 • 533 citations

Human epidermal growth factor: isolation and chemical and biological properties.

1975 • 499 citations

Observations on the social behaviour of cells in tissue culture

1953 • 492 citations

Principles of Cell Motility: The Direction of Cell Movement and Cancer Invasion

1965 • 488 citations

ON THE PERMANENT LIFE OF TISSUES OUTSIDE OF THE ORGANISM

1912 • 473 citations

Topoinhibition and Serum Requirement of Transformed and Untransformed Cells

1970 • 444 citations

Rous Sarcoma Virus: a Function required for the Maintenance of the Transformed State

1970 • 444 citations

Cyclic AMP levels in fibroblasts: Relationship to growth rate and contact inhibition of growth

1971 • 443 citations

Density Dependent Inhibition of Cell Growth in Culture

1967 • 440 citations

Restoration of Several Morphological Characteristics of Normal Fibroblasts in Sarcoma Cells Treated with Adenosine-3′:5′-Cyclic Monophosphate and Its Derivatives

1971 • 440 citations

Basis for the Acquisition of Malignant Potential by Mouse Cells Cultivated in vitro

1968 • 425 citations

“Pleiotypic Response”

1971 • 415 citations

Difference in the Cyclic Adenosine 3′,5′-Monophosphate Levels in Normal and Transformed Cells

1972 • 396 citations

Pituitary Extracts and Steroid Hormones in the Control of 3T3 Cell Growth

1973 • 387 citations

Morphologic Differentiation of Mouse Neuroblastoma Cells induced in vitro by Dibutyryl Adenosine 3′:5′-Cyclic Monophosphate

1971 • 383 citations

Contact inhibition in tissue culture

1970 • 369 citations

AN ENZYMATIC FUNCTION ASSOCIATED WITH TRANSFORMATION OF FIBROBLASTS BY ONCOGENIC VIRUSES

1973 • 368 citations

A partially purified polypeptide fraction from rat liver cell conditioned medium with multiplication‐stimulating activity for embryo fibroblasts

1973 • 335 citations

Transport of Amino Acids by Confluent and Nonconfluent 3T3 and Polyoma Virus-transformed 3T3 Cells Growing on Glass Cover Slips

1969 • 335 citations

Epidermal Growth Factor: Receptors in Human Fibroblasts and Modulation of Action by Cholera Toxin

1973 • 328 citations

Rapid Proliferation of Sublines of NCTC Clone 929 (Strain L) Mouse Cells in a Simple Chemically Defined Medium (MB 752/1)2

1959 • 327 citations

Restoration of Contact-Inhibited Growth to Transformed Cells by Dibutyryl Adenosine 3′:5′-Cyclic Monophosphate

1971 • 321 citations

THE SPECIFIC AMINO ACID REQUIREMENTS OF A HUMAN CARCINOMA CELL (STRAIN H<scp>E</scp>L<scp>A</scp>) IN TISSUE CULTURE

1955 • 320 citations

The metabolism of a poly(A) minus mRNA fraction in HeLa cells

1974 • 317 citations

CONTACT INHIBITION, MACROMOLECULAR SYNTHESIS, AND POLYRIBOSOMES IN CULTURED HUMAN DIPLOID FIBROBLASTS

1965 • 298 citations

Growth Control and Cyclic Alterations of Cyclic AMP in the Cell Cycle

1972 • 292 citations

TRANSPORT CHANGES RAPIDLY INITIATED BY SERUM ADDITION TO “CONTACT INHIBITED” 3T3 CELLS

1969 • 285 citations

Stimulation by serum of multiplication of stationary chicken cells

1971 • 282 citations

The Somatomedins: A Family of Insulinlike Hormones under Growth Hormone Control

1974 • 281 citations

Changes in RNA in relation to growth of the fibroblast: II. The lifetime of mRNA, rRNA, and tRNA in resting and growing cells

1974 • 280 citations

THE SPECIFIC AMINO ACID REQUIREMENTS OF A MAMMALIAN CELL (STRAIN L) IN TISSUE CULTURE

1955 • 279 citations

Regeneration of Rat Liver: Transfer of Humoral Agent by Cross Circulation

1967 • 275 citations

FIBRINOLYSIS ASSOCIATED WITH ONCOGENIC TRANSFORMATION

1973 • 261 citations

Growth control in cultured cells: selection of sublines with increased sensitivity to contact inhibition and decreased tumor-producing ability.

1968 • 256 citations

Social behaviour of cells in tissue culture

1957 • 255 citations

STUDIES ON PRIMARY CULTURES OF DIFFERENTIATED FETAL LIVER CELLS

1972 • 249 citations

Interference microscope studies of cell contacts in tissue culture

1958 • 239 citations

TRANSFORMATION OF PROPERTIES OF AN ESTABLISHED CELL LINE BY SV40 AND POLYOMA VIRUS

1964 • 236 citations

pH as a Determinant of Cellular Growth and Contact Inhibition

1971 • 236 citations

Role of Diffusion Boundary Layer in Contact Inhibition of Growth

1973 • 230 citations

Calcium as a Regulator of the Proliferation of Normal, but Not of Transformed, Chicken Fibroblasts in a Plasma-Containing Medium

1971 • 230 citations

Possible involvement of cyclic GMP in growth control of cultured mouse cells

1974 • 227 citations

Molecular biology of human proteins with special reference to plasma proteins. Vol. 1. Nature and metabolism of extracellular proteins.

1966 • 214 citations

Reduced Adenyl Cyclase Activity in a Polyoma Virus Transformed Cell Line

1968 • 214 citations

Growth Inhibition of Polyoma-Transformed Cells by Contact with Static Normal Fibroblasts

1966 • 210 citations

Attachment and spreading of cells in culture

1961 • 209 citations

The partial purification from calf serum of a fraction with multiplication‐stimulating activity for chicken fibroblasts in cell culture and with non‐suppressible insulin‐like activity

1972 • 209 citations

Epidermal Growth Factor: High and Low Molecular Weight Forms

1970 • 206 citations

THE POPULATION-DEPENDENT REQUIREMENT BY CULTURED MAMMALIAN CELLS FOR METABOLITES WHICH THEY CAN SYNTHESIZE

1962 • 204 citations

Requirement of Serum for DNA Synthesis in BHK 21 Cells : Effects of Density, Suspension and Virus Transformation

1970 • 197 citations

Growth Regulatory Effects of Cellular Interaction

1967 • 197 citations

Role of surface alterations in cell transformation: the importance of proteases and surface proteins

1974 • 192 citations

Reversible arrest of growth in G1 of an established fibroblast line (3T3)

1965 • 189 citations

The control of cellular morphology in embryonic cells infected with Rous sarcoma virus in vitro

1960 • 187 citations

Induction of cell division in medium lacking serum growth factor by SV40

1971 • 185 citations

Control of the Initiation of DNA Synthesis in 3T3 Cells: Serum Factors

1974 • 184 citations

Multiplication‐stimulating activity for chicken embryo fibroblasts from rat liver cell conditioned medium: A family of small polypeptides

1973 • 181 citations

MOLECULAR GROWTH REQUIREMENTS OF SINGLE MAMMALIAN CELLS: THE ACTION OF FETUIN IN PROMOTING CELL ATTACHMENT TO GLASS

1958 • 181 citations

A Factor from a Transformed Cell Line That Affects Cell Migration

1973 • 181 citations

Regulation of Cell Motility by Cyclic AMP

1972 • 179 citations

Changes in RNA in relation to growth of the fibroblast. I. Amounts of mRNA, rRNA, and tRNA in resting and growing cells

1974 • 179 citations

Studies on transformation of hamster cells by polyoma virus in vitro

1961 • 178 citations

Stimulation of Glucose Transport in Cultures of Density-Inhibited Chick Embryo Cells

1971 • 177 citations

The messenger RNA sequences in growing and resting mouse fibroblasts

1975 • 175 citations

Studies on carcinogenesis by avian sarcoma viruses. VI. Differential multiplication of uninfected and of converted cells in response to insulin

1967 • 174 citations

Recent Studies on the Chemistry and Biology of Epidermal Growth Factor

1974 • 169 citations

Pleiotypic Control by Adenosine 3′:5′-Cyclic Monophosphate: A Model for Growth Control in Animal Cells

1973 • 166 citations

Control of macromolecular synthesis in proliferating and resting syrian hamster cells in monolayer culture. I. Ribosome function

1971 • 165 citations

Pleiotypic Control by Cyclic AMP: Interaction with Cyclic GMP and Possible Role of Microtubules

1973 • 165 citations

Regulation of growth and orientation in hamster cells transformed by polyoma virus

1964 • 164 citations

The effect of environmental pH on the growth of normal and malignant cells

1973 • 160 citations

A Portal Blood Factor as the Humoral Agent in Liver Regeneration

1971 • 160 citations

Abortive Transformation by Polyoma Virus

1968 • 156 citations

PRODUCTION AND CHARACTERIZATION OF MULTIPLE-LAYERED POPULATIONS OF ANIMAL CELLS

1965 • 154 citations

Serum Factor Requirements of Normal and Simian Virus 40-Transformed 3T3 Mouse Fibroblasts

1971 • 151 citations

The role of cell‐cell contact in “contact” inhibition of cell division: A review and new evidence

1972 • 150 citations

Cell growth and the initiation of transformation by SV40.

1966 • 150 citations

Cell Culture and Somatic Variation

1964 • 147 citations

Studies of nutrient media for tissue cells in vitro. I. A protein-free chemically defined medium for cultivation of strain L cells.

1956 • 146 citations

Stimulation of cell growth in vitro by serum with and without growth factor Relation to contact inhibition and viral transformation

1970 • 145 citations

Corticosteroid-binding Globulin

1962 • 144 citations

Conditions Limiting Multiplication of Fibroblastic and Epithelial Cells in Dense Cultures

1973 • 141 citations

Regulation of the Synthesis and the Stability of Ribosomal RNA during Contact Inhibition of Growth

1971 • 140 citations

Early alterations in amino acid pools and protein synthesis of diploid fibroblasts stimulated to synthesize DNA by addition of serum

1969 • 140 citations

Isolation of a cationic polypeptide from human serum that stimulates proliferation of 3T3 cells.

1975 • 140 citations

Changes in RNA in relation to growth of the fibroblast. III. Posttranscriptional regulation of mRNA formation in resting and growing cells

1975 • 136 citations

pH AND POPULATION DENSITY IN THE REGULATION OF ANIMAL CELL MULTIPLICATION

1971 • 136 citations

Biochemistry of Cultured Mammalian Cells

1961 • 130 citations

Activation of guanyl cyclase and intracellular cyclic GMP by fibroblast growth factor

1974 • 125 citations

Growth Control in Cell Cultures.

1972 • 125 citations

Adenyl Cyclase in Normal and Transformed Fibroblasts in Tissue Culture

1971 • 124 citations

Conditions Determining Initiation of DNA Synthesis in 3T3 Cells

1970 • 124 citations

Non-suppressible insulin-like activity of human serum I. Physicochemical properties, extraction and partial purification

1966 • 122 citations

Stimulation of Division of Sparse and Confluent 3T3 Cell Populations by a Fibroblast Growth Factor, Dexamethasone, and Insulin

1974 • 121 citations

Purified multiplication-stimulating activity from rat liver cell conditioned medium: Comparison of biological activities with calf serum, insulin, and somatomedin

1974 • 120 citations

Regulation of RNA Synthesis in Fibroblasts During Transition from Resting to Growing State

1973 • 120 citations

Stimulation of Division of Density Inhibited Fibroblasts Glucocorticoids

1973 • 118 citations

THE ROLE OF SERUM IN THE CONTROL OF MULTIPLICATION OF AVIAN AND MAMMALIAN CELLS IN CULTURE

1972 • 118 citations

Migration of Mouse 3T3 Fibroblasts in Response to a Serum Factor

1971 • 117 citations

A Protein Growth Factor for Mammalian Cells in Culture

1958 • 116 citations

Cellular Interactions in Mass Cultures of Human Diploid Fibroblasts

1972 • 114 citations

Studies of cellular adhesiveness

1960 • 113 citations

Purification of a Growth Factor for Ovarian Cells from Bovine Pituitary Glands

1974 • 113 citations

Gene Activation in WI-38 Fibroblasts Stimulated to Proliferate

1972 • 112 citations

Biochemistry of cell walls and membranes

1975 • 110 citations

Role of 3′,5′ -Adenosine Monophosphate in Regulation of Morphology and Growth of Transformed and Normal Fibroblasts

1972 • 109 citations

Changes in RNA metabolism and accumulation of presumptive messenger RNA during transition from the growing to the quiescent state of cultured mouse fibroblasts

1975 • 108 citations

Control of Translation in Cultured Cells: Continued Synthesis and Accumulation of Messenger RNA in Nondividing Cultures

1974 • 105 citations

“Morphologically normal” hamster cells with malignant properties

1963 • 105 citations

Proliferative activity and cytochemical properties of nuclear chromatin related to local cell density of epithelial cells

1970 • 104 citations

Transfer of growth inhibition between normal and virus-transformed cells: autoradiographic studies using marked cells

1967 • 104 citations

Tissue dissociation with proteolytic enzymes *1Adsorption and activity of enzymes at the cell surface

1971 • 104 citations

TISSUE CULTURE POPULATIONS AND THEIR RELATION TO THE TISSUE OF ORIGIN

1960 • 103 citations

Explanation of Degree of Correlation of Sibling Generation Times in Animal Cells

1974 • 102 citations

Contact Inhibition in Colony Formation

1967 • 101 citations

Differentiated Cell Types and the Regulation of Collagen Synthesis

1966 • 101 citations

Studies on Carcinogenesis by Avian Sarcoma Viruses. III. The Differential Effect of Serum and Polyanions on Multiplication of Uninfected and Converted Cells&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;

1966 • 100 citations

Contact regulation of cell division in an epithelial‐like cell line

1968 • 99 citations

Ribosomal RNA Turnover in Contact Inhibited Cells

1972 • 99 citations

One-step growth cycle for BHK21/13 hamster fibroblasts

1970 • 98 citations

The kinetics of serum-induced initiation of DNA synthesis in BHK 21/C13 cells, and the influence of exogenous adenosine

1975 • 97 citations

Cultivation of animal tissues in vitro in nutrients of precisely known constitution.

1946 • 96 citations

Levels of Cyclic AMP in Sparse and Dense Cultures of Growing and Quiescent 3T3 Cells

1972 • 96 citations

Kinetics of Early Changes in Phosphate and Uridine Transport and Cyclic AMP Levels Stimulated by Serum in Density-Inhibited 3T3 Cells

1974 • 92 citations

EFFECT OF PARTIAL HEPATECTOMY ON DNA SYNTHESIS AND MITOSIS IN HETEROTOPIC PARTIAL AUTOGRAFTS OF RAT LIVER.

1964 • 92 citations

Template activity of chromatin during stimulation of cellular proliferation in human diploid fibroblasts

1971 • 90 citations

Temperature-Dependent Properties of Cells Transformed by a Thermosensitive Mutant of Polyoma Virus

1970 • 89 citations

Malignant Transformation of Cells in Vitro

1965 • 89 citations

Contact inhibition of what? An analytical review

1973 • 87 citations

Proteolysis in Stored Serum and its Possible Significance in Cell Culture

1960 • 84 citations

Human sarcoma cells in culture

1970 • 83 citations

Transformation of mouse cell line 3T3 by SV40: Dose response relationship and correlation with SV40 tumor antigen production

1966 • 83 citations

Intracellular Cyclic AMP Concentration Responds Specifically to Growth Regulation by Serum

1974 • 82 citations

Oxygen microenvironment and respiratory oscillations in cultured mammalian cells

1974 • 75 citations

Effect of Insulin on the Growth Pattern and Adenylate Cyclase Activity of BHK Fibroblasts

1973 • 72 citations

Cell locomotion and contact inhibition of normal and neoplastic rat cells

1973 • 72 citations

Shaking 3T3 cells: Further studies on diffusion boundary effects

1974 • 71 citations

Density inhibition of motility in 3T3 fibroblasts and their SV40 transformants

1971 • 70 citations

A Serum-Free Nutrient Solution Sustaining Rapid and Continuous Proliferation of Strain L (Earle) Mouse Cells&lt;xref ref-type="fn" rid="fn1"&gt;2&lt;/xref&gt;

1956 • 70 citations

Long-term cultivation of mammalian cell strains in protein- and lipid-free chemically defined synthetic media

1971 • 69 citations

Contact Inhibition of Transformed Cells Incompletely Restored by Dibutyryl Cyclic AMP

1972 • 69 citations

Parallel orientation of fibroblasts in vitro

1968 • 68 citations

MORPHOGENETIC ASPECTS OF MULTILAYERING IN PETRI DISH CULTURES OF HUMAN FETAL LUNG FIBROBLASTS

1969 • 68 citations

Serum dependent growth of primary cultured differentiated fetal rat hepatocytes in arginine‐deficient medium

1973 • 68 citations

Isolation and characterization of revertant cell lines. IV. Direct selection of serum‐revertant sublines of SV40‐transformed 3T3 mouse cells

1973 • 67 citations

Opposite effects of dibutyryl adenosine 3′:5′ cyclic monophosphate and serum on growth of Chinese hamster cells

1972 • 66 citations

Growth of fibroblasts on linear and planar anchorages of limiting dimensions

1973 • 65 citations

LOCAL STIMULATION OF GROWTH IN PRIMARY CULTURES OF CHICK EMBRYO FIBROBLASTS

1969 • 64 citations

Evaluation of a humoral factor in liver regeneration utilizing liver transplants.

1971 • 63 citations

The Nutrition of Animal Cells

1954 • 63 citations

Wound healing processes in cell cultures

1969 • 62 citations

CULTIVATION OF MAMMALIAN CELLS IN DEFINED MEDIA WITH PROTEIN AND NONPROTEIN SUPPLEMENTS

1966 • 61 citations

Effect of a Fibroblast Growth Factor, Insulin, Dexamethasone, and Serum on the Morphology of BALB/c 3T3 Cells

1974 • 61 citations

Isolation and characterization of revertant cell lines. III. Isolation of density‐revertants of SV40‐transformed 3T3 cells using colchicine

1973 • 60 citations

Contact-dependent Behavior of Normal Cells and the Possible Significance of Surface Changes in Virus-induced Transformation

1962 • 60 citations

Serumless Medium for Cultivation of Cells of Normal and Malignant Origin.

1960 • 59 citations

Cyclic 3′:5′ AMP and cell proliferation in cultures of embryonic rat cells

1972 • 59 citations

Growth Response to Hormones by a New Rat Ovary Cell Line

1972 • 58 citations

Role of Cyclic 3′:5′-Adenosine Monophosphate in the Early Transport Changes Induced by Serum and Insulin in Quiescent Fibroblasts

1973 • 58 citations

TISSUE CULTURE AND CELL PHYSIOLOGY

1924 • 58 citations

Nonidentity of Fetuin and Protein Growth (Flattening) Factor

1959 • 58 citations

The need for direct cell contact in “contact” inhibition of cell division in culture

1968 • 57 citations

Differences in the cytoplasmic distribution of newly synthesized poly(A) in serum-stimulated and resting cultures of BALB/c 3T3 cells

1975 • 57 citations

Growth Inhibitor of Hamster Fibroblast Cells

1966 • 57 citations

THE SUSTAINED GROWTH OF HUMAN AND ANIMAL CELLS IN A PROTEIN-FREE ENVIRONMENT

1960 • 56 citations

Rate of RNA Synthesis in Ghost Monolayers obtained from Fibroblasts Preparing for Division

1973 • 55 citations

ph, serum and Zn⁺⁺ in the regulation of DNA synthesis in cultures of chick embryo cells

1973 • 52 citations

Flattening, movement and control of division of epithelial-like cells

1970 • 51 citations

The Utilization of Proteins by Cultured Human Cells

1960 • 51 citations

Effects of steroids on growth of an androgen-dependent mouse mammary carcinoma in cell culture

1972 • 51 citations

Replication of polyoma virus DNA

1968 • 50 citations

Control of division by cell contact and serum concentration in cultures of 3T3 cells*1

1971 • 50 citations

Changes in the properties of cell-substrate adhesion during cultivation of chicken fibroblasts in vitro in a serum-free medium

1971 • 50 citations

Dissociation between inhibition of movement and inhibition of division in RSV transformed human fibroblasts

1967 • 50 citations

The basis of the tumorigenicity of BHK 21 cells

1968 • 49 citations

Properties of two growth-stimulating proteins isolated from fetal calf serum

1973 • 48 citations

Optimal conditions for the study of growth control in BALB/c 3T3 fibroblasts

1975 • 48 citations

The role of serum and fetuin in the growth of monkey kidney cells in culture

1969 • 47 citations

Isolation, purification, and chemical characterization of the serum mitogen for diploid human fibroblasts

1973 • 46 citations

The mechanism of cell binding and cell-sheet formation in L strain fibroblasts

1960 • 46 citations

Purification of a serum protein required by a mammalian cell in tissue culture

1957 • 46 citations

The control of serum protein synthesis in hepatoma-fibroblast hybrids

1975 • 45 citations

Serum requirements for survival of 3T3 and SV3T3 fibroblasts

1972 • 45 citations

Prolonged survival of excised animal tissues in vitro in nutrients of known constitution

1949 • 43 citations

Quiescent SV40 virus transformed 3T3 cells in culture

1973 • 43 citations

Isolation and characterization of revertant cell lines. II. Growth control of a polyploid revertant line derived from SV40‐transformed 3T3 mouse cells

1973 • 43 citations

Defective Formation of the Lamellar Cytoplasm by Neoplastic Fibroblasts

1972 • 42 citations

A Chemically Defined Medium for Growth of Animal Cells in Suspension

1963 • 42 citations

Reversible injury of L-strain mouse cells by trypsin

1960 • 41 citations

The Leeuwenhoek Lecture, 1971 - Tumour viruses and the sociology of fibroblasts

1972 • 41 citations

STUDIES ON THE GROWTH OF TISSUES IN VITRO

1933 • 40 citations

Proliferation control of cultivated human glia-like cells under ?steady state? conditions*1

1971 • 40 citations

Interaction between normal and transformed bovine fibroblasts in culture: I. cells transformed by rous sarcoma virus

1967 • 40 citations

“Spontaneous” neoplastic transformation in vitro: the ultrastructure of the tissue culture cell

1970 • 39 citations

The response of normal and polyoma virus‐transformed BHK/21 cells to exogenous purines

1973 • 38 citations

Tissue Homeostasis and the Biological Basis of Cancer

1968 • 37 citations

The influence of normal cells on the proliferation of tumour cells in culture

1970 • 37 citations

Control of cell multiplication in uninfected chicken cells and chicken cells converted by avian sarcoma viruses

1969 • 37 citations

Hormone-Secreting and Hormone-Responsive Cell Cultures

1970 • 36 citations

Direct Isolation and Characterization of “Flat” SV40-transformed Cells

1971 • 34 citations

The choline and serum protein requirements of mouse fibroblast cells (Strain LS) in culture

1969 • 33 citations

Adaptation of Tissue Culture Cells to a Serum-Free Medium

1958 • 33 citations

Contact Inhibition of Movement in the Cultures of Transformed Cells

1973 • 33 citations

Influence of serum protein on determination of nutritional requirements of cells in culture

1962 • 32 citations

Species Specificity in Growth Regulatory Effects of Cellular Interaction

1968 • 31 citations

Growth of Mammalian Cells in a Heat-stable Dialysable Medium

1965 • 31 citations

Bertrand Russell

1972 • 30 citations

Contact inhibition of speed in 3T3 and its independence from postconfluence inhibition of cell division

1973 • 29 citations

The monolayering in tissue culture of fibroblasts from different sources

1968 • 28 citations

Increased RNA Synthesis in Nuclear Monolayers of WI-38 Cells Stimulated to Proliferate

1974 • 28 citations

Growth limitation of 3T3 mouse fibroblasts by available growth surface area and medium components

1975 • 27 citations

Density dependent stimulation of thymidine incorporation in BHK2l cells by active material released from the same cells

1971 • 26 citations

Mitotic response in liver autograft after partial hepatectomy in the rat

1964 • 25 citations

Association of polyanion resistance with tumorigenicity and other properties in BHK/21 cells

1974 • 24 citations

Appendix: Short-range diffusion gradients

1974 • 24 citations

Studies on a Serum Substitute for Mammalian Cells in Culture I. Biological Efficacy of Whole and Fractionated Peptone Dialysate

1972 • 24 citations

A growth factor for animal cells derived from peptone

1973 • 24 citations

The effects of low molecular weight materials derived from animal tissues on the growth of animal cells in vitro

1968 • 24 citations

The Utilisation of Proteoses by Chicken Heart Fibroblasts Growing in vitro

1932 • 24 citations

Interaction between normal and transformed bovine fibroblasts in culture: II cells transformed by polyoma virus

1968 • 24 citations

The stimulation of growth of mammalian cells in vitro by a peptide fraction from enzymatic digests of serum

1966 • 23 citations

Further manifestations of abortive transformation of bhk 21 cells by polyoma virus

1971 • 22 citations

Phenotypic variation and its control in polyoma-transformed BHK21 cells

1971 • 22 citations

Are Macromolecules Required for Growth of Single Isolated Mammalian Cells?

1960 • 19 citations

Contact inhibition, polyribosomes, and cell surface membranes in cultured mammalian cells

1974 • 18 citations

Differences in Inositol Requirements of Several Strains of HeLa, Conjunctival and Amnion Cells.

1958 • 17 citations

Effects of withdrawal of a serum stimulus on the protein-synthesizing machinery of cultured fibroblasts

1975 • 16 citations

An inhibitor present in calf serum which prevents growth of BHK21 cells in suspension culture

1972 • 16 citations

STUDIES ON THE GROWTH OF TISSUES IN VITRO : II. AN ANALYSIS OF THE GROWTH OF CHICK HEART FIBROBLASTS IN A HANGING DROP OP FLUID MEDIUM

1933 • 16 citations

Separation of Growth Promoting Activity from Horse Serum by Dialysis.

1960 • 16 citations

Growth promoting activity for mammalian cells in fractions of tissue extracts

1965 • 15 citations

The effects of topoinhibition and cytochalasin B on metabolic cooperation

1975 • 15 citations

Cell Division in Medium lacking Serum Growth Factor: Comparison of Lines transformed by Different Agents

1971 • 14 citations

Non-reciprocal density-dependent mitotic inhibition in mixed cultures of embryonic chick and mouse fibroblasts

1971 • 13 citations

Growth regulation and tumour formation of normal and neoplastic rat cells

1973 • 13 citations

SECTION OF PLANETARY SCIENCES: SOME PHYSICAL ASPECTS OF FLOW NEAR SURFACES*

1963 • 5 citations

Some Aspects of Localization of Tumours for Radiotherapy

1973 • 1 citations