The role of cell‐cell contact in “contact” inhibition of cell division: A review and new evidence

The serial cultivation of human diploid cell strains

1961 • 7,886 citations

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

1963 • 2,742 citations

Agar suspension culture for the selective assay of cells transformed by polyoma virus

1964 • 1,265 citations

The initiation of cell division in a contact‐inhibited mammalian cell line

1965 • 807 citations

Development of 3T3‐like lines from Balb/c mouse embryo cultures: Transformation susceptibility to SV40

1968 • 662 citations

Observations on the social behaviour of cells in tissue culture

1954 • 606 citations

"Contact inhibition" of cell division in 3T3 cells.

1968 • 547 citations

Observations on the social behaviour of cells in tissue culture

1953 • 492 citations

Density Dependent Inhibition of Cell Growth in Culture

1967 • 440 citations

Basis for the Acquisition of Malignant Potential by Mouse Cells Cultivated in vitro

1968 • 425 citations

Chapter 4 Low-Resistance Junctions Between Cells in Embryos and Tissue Culture

1968 • 349 citations

Transport of Amino Acids by Confluent and Nonconfluent 3T3 and Polyoma Virus-transformed 3T3 Cells Growing on Glass Cover Slips

1969 • 335 citations

Metabolic co-operation between biochemically marked mammalian cells in tissue culture

1969 • 325 citations

Biological Effects of Freezing and Supercooling

1962 • 307 citations

CONTACT INHIBITION, MACROMOLECULAR SYNTHESIS, AND POLYRIBOSOMES IN CULTURED HUMAN DIPLOID FIBROBLASTS

1965 • 298 citations

TRANSPORT CHANGES RAPIDLY INITIATED BY SERUM ADDITION TO “CONTACT INHIBITED” 3T3 CELLS

1969 • 285 citations

THE RELATIONSHIP OF THE CELL CYCLE TO TUMOR GROWTH AND CONTROL OF CELL DIVISION: A REVIEW.

1965 • 272 citations

Growth control in cultured cells: selection of sublines with increased sensitivity to contact inhibition and decreased tumor-producing ability.

1968 • 256 citations

Social behaviour of cells in tissue culture

1957 • 255 citations

A quantitative cytochemical investigation of the relationship between cell mass and initiation of DNA synthesis in mouse fibroblasts in vitro

1965 • 251 citations

Quantitative cytochemical studies on interphase growth

1965 • 244 citations

Current Topics in Developmental Biology

1968 • 244 citations

Pacemaker activity and mitosis in cultures of newborn rat heart ventricle cells

1966 • 240 citations

TRANSFORMATION OF PROPERTIES OF AN ESTABLISHED CELL LINE BY SV40 AND POLYOMA VIRUS

1964 • 236 citations

Effects of local cell concentrations upon the growth of chick embryo cells in tissue culture

1968 • 213 citations

Growth Inhibition of Polyoma-Transformed Cells by Contact with Static Normal Fibroblasts

1966 • 210 citations

Growth Regulating Substances for Animal Cells in Culture.

1968 • 210 citations

Growth Regulatory Effects of Cellular Interaction

1967 • 197 citations

EFFECTS OF TEMPERATURE ON GROWTH RATE OF CULTURED MAMMALIAN CELLS (L5178Y)

1967 • 191 citations

Reversible arrest of growth in G1 of an established fibroblast line (3T3)

1965 • 189 citations

Analysis of the Life-Cycle in Mammalian Cells

1963 • 187 citations

Chromosomal Evolution in Cell Populations

1962 • 157 citations

PRODUCTION AND CHARACTERIZATION OF MULTIPLE-LAYERED POPULATIONS OF ANIMAL CELLS

1965 • 154 citations

Cell Maturation and Tissue Organization in Epithelial Outgrowths from Skin and Buccal Mucosa In Vitro*

1967 • 132 citations

Conditions Determining Initiation of DNA Synthesis in 3T3 Cells

1970 • 124 citations

Regulation of proliferation and movement of human glialike cells in culture

1969 • 113 citations

Inhibition of the division cycle in confluent cultures of human fibroblasts in vitro

1966 • 112 citations

Variations in the generation times of a strain of rat sarcoma cells in culture

1965 • 111 citations

Control of Somatic Cell Mitosis by Simulated Changes in the Transmembrane Potential Level

1971 • 107 citations

Variation of the Transmembrane Potential Level as a Basic Mechanism of Mitosis Control

1970 • 103 citations

Contact Inhibition in Colony Formation

1967 • 101 citations

Studies on properties of surfaces required for growth of mammalian cells in synthetic medium

1960 • 101 citations

Contact regulation of cell division in an epithelial‐like cell line

1968 • 99 citations

Cell surface membranes in close contact role of calcium and magnesium ions

1967 • 98 citations

SECTION OF BIOLOGICAL AND MEDICAL SCIENCES: ELECTROOSMOTIC INTERACTIONS ACCOMPANYING MITOSIS INITIATION IN SARCOMA CELLS IN VITRO*

1969 • 95 citations

Properties of Syrian hamster cells transformed in the presence of carcinogenic hydrocarbons

1967 • 91 citations

Antigenic and cultural properties of cells doubly transformed by polyoma virus and SV40

1965 • 90 citations

Malignant Transformation of Cells in Vitro

1965 • 89 citations

Stimulation of RNA synthesis and cell division in resting cells by a factor present in serum.

1967 • 82 citations

Mammalian cell growth proteins. I. Growth stimulation of fetuin.

1968 • 81 citations

Growth Factors for Mammalian Cells in Culture

1959 • 81 citations

In vitro malignant transformation of cells derid from mouse prostate in the presence of 3-methylcholanthrene.

1969 • 78 citations

A DIFFUSIBLE FACTOR WHICH SUSTAINS CONTACT INHIBITION OF REPLICATION

1969 • 76 citations

Control of nucleic acid synthesis in human diploid cells undergoing contact inhibition

1968 • 73 citations

Characteristics of a Hamster Cell Clone Transformed by Polyoma Virus<xref ref-type="fn" rid="FN2">2</xref>

1963 • 68 citations

MITOTIC AND NONMITOTIC MULTIPLE-LAYERED PERFUSION CULTURES

1969 • 68 citations

Parallel orientation of fibroblasts in vitro

1968 • 68 citations

LOCAL STIMULATION OF GROWTH IN PRIMARY CULTURES OF CHICK EMBRYO FIBROBLASTS

1969 • 64 citations

Wound healing processes in cell cultures

1969 • 62 citations

Study of pigment donation in vitro

1968 • 59 citations

The need for direct cell contact in “contact” inhibition of cell division in culture

1968 • 57 citations

Establishment of a cell line from an inbred mouse strain for viral transformation studies: simian virus 40 transformation and tumor production.

1968 • 57 citations

Studies on the transformation of hamster embryo cells in culture by polyoma virus

1963 • 53 citations

Synchronized cell division induced by medium change

1967 • 53 citations

Flattening, movement and control of division of epithelial-like cells

1970 • 51 citations

Dissociation between inhibition of movement and inhibition of division in RSV transformed human fibroblasts

1967 • 50 citations

Chemical changes in chick embryo cells infected with Rous sarcoma virus in vitro

1962 • 49 citations

Relationship of contact inhibition to tumor transplantability, morphology, and growth rate.

1969 • 47 citations

Migration and proliferation of diploid human fibroblasts following “wounding” of confluent monolayers

1969 • 46 citations

Cultivation <italic>In Vitro</italic> of Cells Derived From Adult C3H Mouse Ventral Prostate<xref ref-type="fn" rid="FN2">2</xref>

1969 • 44 citations

Aspects of Cell Individuality in the Renewal of Stratified Squamous Epithelia

1964 • 44 citations

Influence of Cell Density on Growth Inhibition of Human Fibroblasts in vitro

1967 • 43 citations

Tight junctions between contact-inhibited cells in vitro

1969 • 43 citations

Interaction between normal and transformed bovine fibroblasts in culture: I. cells transformed by rous sarcoma virus

1967 • 40 citations

Tissue Homeostasis and the Biological Basis of Cancer

1968 • 37 citations

Increase in the size of chick embryo cells upon cultivation in serum-containing medium

1968 • 30 citations

A simple mechanical method for the efficient release of contact inhibition

1969 • 29 citations

Properties of a hybrid between lines sensitive and insensitive to contact inhibition of cell division

1968 • 28 citations

SUMMATION OF THE SESSION ON TOXICOLOGY AND PHYSIOLOGY

1969 • 28 citations

The locomotory behaviour of small groups of fibroblasts

1965 • 27 citations

Stimulation of macromolecular processes in BSC1 cells due to medium replenishment

1968 • 26 citations

Distribution in tissue homogenates, and the nature of the linkage of injected proteins to subcellular particles

1967 • 25 citations

Structure of Normal and Polyoma Virus-Transformed Hamster Cell Cultures

1966 • 21 citations

The relation of karyotypic change to loss of contact inhibition of division in human diploid cells after SV₄₀ infection

1967 • 12 citations

Short-range Factors Affecting Cell Growth and Movement

1967 • 11 citations

Density dependent inhibition of cell growth in cultures of primary and established lines of cells

1969 • 9 citations

Growth of mouse fibroblasts in the presence of irradiated and lyophilized monolayers of the same type of cells

1968 • 8 citations

An interaction between neighbouring cells

1967 • 7 citations

Reversal of Contact-Inhibition in Primary Amnion Cultures by Hydrocortisone

1966 • 4 citations