Supersensitivity of Benzodiazepine Receptors in Hepatic Encephalopathy Due to Fulminant Hepatic Failure in the Rat: Reversal by a Benzodiazepine Antagonist

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Selective antagonists of benzodiazepines

1981 • 1,235 citations

GABA‐Benzodiazepine‐Barbiturate Receptor Interactions

1981 • 910 citations

GABAergic modulation of benzodiazepine binding site sensitivity

1978 • 726 citations

The effects of age and liver disease on the disposition and elimination of diazepam in adult man.

1975 • 693 citations

Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors.

1983 • 631 citations

An endogenous protein modulates the affinity of GABA and benzodiazepine receptors in rat brain

1978 • 467 citations

Influences ions, enzymes, and detergents on gamma-aminobutyric acid-receptor binding in synaptic membranes of rat brain.

1977 • 384 citations

Synergism between mercaptans and ammonia or fatty acids in the production of coma: a possible role for mercaptans in the pathogenesis of hepatic coma.

1974 • 263 citations

Normal Disposition of Oxazepam in Acute Viral Hepatitis and Cirrhosis

1976 • 238 citations

Stimulation of benzodiazepine receptor binding by gamma-aminobutyric acid.

1979 • 220 citations

CGS 8216: Receptor binding characteristics of a potent benzodiazepine antagonist

1982 • 192 citations

Effect of age and parenchymal liver disease on the disposition and elimination of chlordiazepoxide (Librium)

1978 • 165 citations

Facilitation of benzodiazepine binding by sodium chloride and GABA

1978 • 164 citations

Intravenous administration of diazepam in patients with chronic liver disease.

1976 • 134 citations

Increased blood-brain transfer in a rabbit model of acute liver failure

1983 • 133 citations

Experimental Hepatic Encephalopathy: Changes in the Binding of γ-Aminobutyric Acid

1982 • 126 citations

Gamma-aminobutyric acid and benzodiazepine receptors in an animal model of fulminant hepatic failure.

1983 • 107 citations

GLIAL AND NEURONAL CHANGES IN EXPERIMENTAL HEPATIC ENCEPHALOPATHY: A quantitative morphological investigation

1978 • 80 citations

GABA Receptors in Clonal Cell Lines: A Model for Study of Benzodiazepine Action at Molecular Level

1979 • 62 citations

GABAergic denervation of rat substantia nigra: functional and pharmacological properties

1980 • 57 citations

Visual Evoked Potentials in Encephalopathy Induced by Galactosamine, Ammonia, Dimethyldisulfide, and Octanoic Acid

2007 • 56 citations

Metabolism and Brain Uptake of γ‐Aminobutyric Acid in Galactosamine‐Induced Hepatic Encephalopathy in Rats

1982 • 56 citations

The Benzodiazepine Receptor

1981 • 49 citations

Perspectives in hepatic encephalopathy.

1982 • 46 citations

Comparative evaluation of visual evoked potentials in experimental hepatic encephalopathy and in pharmacologically induced coma-like states in rat

1981 • 43 citations

Isolation, characterization, and purification to homogeneity of a rat brain protein (GABA-modulin).

1982 • 42 citations

1,4-Benzodiazepines and Gamma-Aminobutyric Acid: Pharmacological and Biochemical Correlates

1979 • 38 citations

Phosphorylation induces a decrease in the biological activity of the protein inhibitor (GABA-modulin) of gamma-aminobutyric acid binding sites.

1983 • 35 citations

The E.E.G. in hepatic encephalopathy.

1963 • 35 citations

Increase in Striatal [³H]Muscimol Binding Following Intrastriatal Injection of Kainic Acid: A Denervation Supersensitivity Phenomenon

1980 • 34 citations

Denervation supersensitivity for benzodiazepine receptors in the rat substantia nigra

1981 • 28 citations

Incorporation of D-[1-14C]galactosamine into serum proteins and tissues of the rat

1965 • 24 citations

Endogenous regulators of benzodiazepine recognition sites

1980 • 24 citations

Benzodiazepines: a tool to explore the biochemical and neurophysiological basis of anxiety.

1980 • 24 citations

Toxins in Hepatic Encephalopathy: The Role of the Synergistic Effect of Ammonia, Mercaptans and Short Chain Fatty Acids

1984 • 20 citations

Benzodiazepine receptors: autoradiographical and immunocytochemical evidence for their localization in regions of GABAergic synaptic contacts.

1981 • 15 citations

Ethylenediamine and GABA Potentiation of [³H]Diazepam Binding to Benzodiazepine Receptors in Rat Cerebral Cortex

1982 • 15 citations

A case of brain atrophy after fulminant hepatic failure.

1983 • 9 citations

Cortical and optic atrophy following fulminant hepatic failure.

1977 • 9 citations

γ-Aminobutyric Acid Receptors in Experimental Hepatic Encephalopathy

1984 • 7 citations

Evidence suggesting denervation supersensitivity of nigral GABA receptors following destruction of the striatonigral GABA pathway in the rat [proceedings].

1978 • 6 citations