Transcription of a transposed trypanosome surface antigen gene starts upstream of the transposed segment.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Studies on transformation of Escherichia coli with plasmids

1983 • 11,179 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Trans-complementable copy-number mutants of plasmid ColE1

1980 • 975 citations

Identification, purification and properties of clone-specific glycoprotein antigens constituting the surface coat ofTrypanosoma brucei

1975 • 917 citations

Spliced early mRNAs of simian virus 40

1978 • 817 citations

Structure of the adenovirus 2 early mRNAs

1978 • 591 citations

Antigenic variation in trypanosoma brucei analyzed by electrophoretic separation of chromosome-sized DNA molecules

1984 • 368 citations

Antigenic variation in trypanosomes

1978 • 329 citations

Tubulin genes are tandemly linked and clustered in the genome of trypanosoma brucei

1983 • 265 citations

Activation of trypanosome surface glycoprotein genes involves a duplication-transposition leading to an altered 3′ end

1981 • 258 citations

An analysis of cosmid clones of nuclear DNA fromTrypanosoma bruceishows that the genes for variant surface glycoproteins are clustered in the genome

1982 • 246 citations

Growth of chromosome ends in multiplying trypanosomes

1983 • 244 citations

Transcripts coding for variant surface glycoproteins of Trypanosoma brucei have a short, identical exon at their 5′ end

1982 • 243 citations

Novel expression-linked copies of the genes for variant surface antigens in trypanosomes

1980 • 240 citations

α-Amanitin-insensitive transcription of variant surface glycoprotein genes provides further evidence for discontinuous transcription in trypanosomes

1984 • 228 citations

Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes

1984 • 193 citations

RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes

1982 • 183 citations

Identification of a small rna containing the trypanosome spliced leader: A donor of shared 5′ sequences of trypanosomatid mRNAs?

1984 • 176 citations

Gene conversion as a mechanism for antigenic variation in Trypanosomes

1983 • 167 citations

Trypanosome mRNAs share a common 5′ spliced leader sequence

1984 • 163 citations

Calmodulin genes in trypanosomes are tandemly repeated and produce multiple mRNAs with a common 5' leader sequence.

1985 • 162 citations

Chromosome rearrangements in trypanosoma brucei

1984 • 161 citations

The isolation of plasmids containing dna complementary to messenger rna for variant surface glycoproteins of Trypanosoma brucei

1980 • 161 citations

Characterization of the DNA duplication-transposition that controls the expression of two genes for variant surface glycoproteins in Trypanosoma brucei

1982 • 154 citations

Antigenic variation in trypanosomes

1978 • 152 citations

Tandem repetition of the 5′ mini-exon of variant surface glycoprotein genes: A multiple promoter for VSG gene transcription?

1983 • 152 citations

Comparison of the genes coding for the common 5′ terminal sequence of messenger RNAs in three trypanosome species

1984 • 150 citations

Discontinuous synthesis of mRNA in trypanosomes.

1984 • 145 citations

Sequences homologous to the variant antigen mRNA spliced leader are located in tandem repeats and variable orphons in Trypanosoma brucei

1983 • 143 citations

Genomic environment of T. brucei VSG genes: presence of a minichromosome

1982 • 143 citations

The transposition unit of variant surface glycoprotein gene 118 of Trypanosoma brucei

1983 • 138 citations

Isolation and characterization of kinetoplast DNA from bloodstream form of Trypanosoma brucei.

1978 • 134 citations

Many trypanosome messenger RNAs share a common 5′ terminal sequence

1984 • 120 citations

Activation of the genes for variant surface glycoproteins 117 and 118 in Trypanosoma brucei

1983 • 113 citations

Variant surface glycoproteins of Trypanosoma brucei are synthesised with cleavable hydrophobic sequences at the carboxy and amino termini

1981 • 111 citations

Two modes of activation of a single surface antigen gene of trypanosoma brucei

1984 • 110 citations

The expression-linked copy of surface antigen gene in Trypanosoma is probably the one transcribed

1981 • 105 citations

The 5′-limit of transposition and upstream barren region of a trypanosome VSG gene: tandem 76 base-pair repeats flanking (TAA)₉₀

1984 • 104 citations

Tubulin genes of Trypanosoma brucei: a tightly clustered family of alternating genes.

1983 • 100 citations

Mature mRNAs ofTrypanosoma bruceipossess a 5′ cap acquired by discontinuous RNA synthesis

1985 • 95 citations

Analysis of genomic rearrangements associated with two variable antigen genes of Trypanosoma brucei

1982 • 85 citations

Two mechanisms of expression of a predominant variant antigen gene of Trypanosoma brucei

1984 • 77 citations

Sequences homologous to variant antigen mRNA spliced leader in Trypanosomatidae which do not undergo antigenic variation

1984 • 66 citations

At least two transposed sequences are associated in the expression site of a surface antigen gene in different Trypanosome clones

1983 • 54 citations

The control of variant surface antigen synthesis in trypanosomes

1983 • 51 citations

Structure and Transcription of a Telomeric Surface Antigen Gene of Trypanosoma brucei

1985 • 48 citations

Structure and expression of aTrypanosoma brucei gambiensevariant specific antigen gene

1982 • 47 citations

Characterization of the expression-linked gene copies of variant surface glycoprotein 118 in two independently isolated clones ofTrypanosoma brucel

1982 • 46 citations

Two simultaneously active VSG gene transcription units in a single trypanosoma brucei variant

1985 • 45 citations

Translocation alters the activation rate of a trypanosome surface antigen gene

1984 • 41 citations

Antigenic variation of trypanosomes

1985 • 27 citations

Activation of genes for variant surface glycoproteins in trypanosomes.

1984 • 3 citations