Telomerase Activity in Candidate Stem Cells From Fetal Liver and Adult Bone Marrow

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1994 • 7,043 citations

Telomeres shorten during ageing of human fibroblasts

1990 • 5,530 citations

Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

1997 • 2,256 citations

The RNA Component of Human Telomerase

1995 • 2,243 citations

Telomere length predicts replicative capacity of human fibroblasts.

1992 • 2,209 citations

Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA

1997 • 2,086 citations

hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization

1997 • 1,786 citations

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

1989 • 1,607 citations

Telomerase activity in human germline and embryonic tissues and cells

1996 • 1,345 citations

Telomere loss: mitotic clock or genetic time bomb?

1991 • 1,144 citations

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

1994 • 1,133 citations

Telomere end-replication problem and cell aging

1992 • 1,044 citations

Activation of telomerase in human lymphocytes and hematopoietic progenitor cells.

1995 • 871 citations

Heterogeneity in telomere length of human chromosomes

1996 • 861 citations

Telomeres: Beginning to Understand the End

1995 • 855 citations

Telomerase activity in normal and malignant hematopoietic cells.

1995 • 748 citations

Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes.

1993 • 743 citations

TLC1 : Template RNA Component of Saccharomyces cerevisiae Telomerase

1994 • 727 citations

Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro

1989 • 699 citations

Developmental and tissue-specific regulation of mouse telomerase and telomere length.

1995 • 686 citations

Correlating telomerase activity levels with human neuroblastoma outcomes

1995 • 631 citations

Telomerase activity in normal leukocytes and in hematologic malignancies

1995 • 619 citations

Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells.

1994 • 529 citations

Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes.

1996 • 494 citations

Telomerase Activity in Small-Cell and Non-Small-Cell Lung Cancers

1995 • 447 citations

Telomerase Activity in Human Breast Tumors

1996 • 440 citations

Regulated expression of telomerase activity in human T lymphocyte development and activation.

1996 • 416 citations

Ontogeny-related changes in proliferative potential of human hematopoietic cells.

1993 • 413 citations

Telomerase activity: a prevalent marker of malignant human prostate tissue.

1996 • 394 citations

Differential Expression of Telomerase Activity in Hematopoietic Progenitors from Adult Human Bone Marrow

1996 • 390 citations

Telomerase and DNA End Replication: No Longer a Lagging Strand Problem?

1995 • 385 citations

Telomerase Activity in Hematopoietic Cells Is Associated with Self-Renewal Potential

1996 • 385 citations

Functional Characterization and Developmental Regulation of Mouse Telomerase RNA

1995 • 366 citations

Regulation of Telomerase Activity in Immortal Cell Lines

1996 • 360 citations

Runaway telomere elongation caused by telomerase RNA gene mutations

1995 • 338 citations

Telomeres: No end in sight

1994 • 322 citations

Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas.

1995 • 313 citations

Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis

1996 • 291 citations

Differentiation of immortal cells inhibits telomerase activity.

1995 • 269 citations

Telomerase activity in normal human epithelial cells.

1996 • 248 citations

Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow.

1992 • 231 citations

Telomerase regulation during entry into the cell cycle in normal human T cells.

1996 • 206 citations

Refining the telomere-telomerase hypothesis of aging and cancer

1996 • 170 citations

Telomerase Activation in Mouse Mammary Tumors: Lack of Detectable Telomere Shortening and Evidence for Regulation of Telomerase RNA with Cell Proliferation

1996 • 157 citations

Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro

1989 • 121 citations

Self-Renewal of Stem Cells

1998 • 89 citations

Telomerase activity in vivo in human malignant hematopoietic cells.

1994 • 83 citations

Telomerase Activity Is Induced by the Stimulation to Antigen Receptor in Human Peripheral Lymphocytes

1996 • 83 citations

Maintenance of hematopoiesis in serum-free bone marrow cultures involves sequential recruitment of quiescent progenitors.

1993 • 69 citations

Frequency of Fetal Cells in Sorted Subpopulations of Nucleated Erythroid and CD34+ Hematopoietic Progenitor Cells From Maternal Peripheral Blood

1997 • 62 citations