Naturally occurring and axotomy-induced motoneuron death and its prevention by neurotrophic agents: a comparison between chick and mouse

Cell Death During Development of the Nervous System

1991 • 3,033 citations

The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons

1992 • 752 citations

Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section

1992 • 712 citations

Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death

1992 • 668 citations

Cell death in the development of the lateral motor column of the chick embryo

1975 • 658 citations

Neurotrophins promote motor neuron survival and are present in embryonic limb bud

1993 • 619 citations

An immunohistochemical study of the nerve growth factor receptor in developing rats

1988 • 610 citations

Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy

1992 • 559 citations

Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo

1993 • 537 citations

Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death

1992 • 458 citations

Control of Embryonic Motoneuron Survival in Vivo by Ciliary Neurotrophic Factor

1991 • 448 citations

The neurotrophic theory and naturally occurring motoneuron death

1989 • 397 citations

Naturally Occurring Neuronal Death in Vertebrates

1990 • 389 citations

Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: Evidence for the role of cell death genes

1990 • 332 citations

Cellular Pattern of Insulin-Like Growth Factor-I (IGF-I) and Type I IGF Receptor Gene Expression in Early Organogenesis: Comparison with IGF-II Gene Expression

1990 • 320 citations

Cell death of motoneurons in the chick embryo spinal cord. I. A light and electron microscopic study of naturally occurring and induced cell loss during development

1978 • 318 citations

Cell death of motoneurons in the chick embryo spinal cord. IV. Evidence that a functional neuromuscular interaction is involved in the regulation of naturally occurring cell death and the stabilization of synapses

1979 • 299 citations

Neuromuscular blockade increases motoneurone survival during normal cell death in the chick embryo

1978 • 246 citations

Motoneuron cell death in the developing lumbar spinal cord of the mouse

1982 • 232 citations

Insulin‐like growth factors: Putative muscle‐derived trophic agents that promote motoneuron survival

1993 • 225 citations

Motoneuron death after sciatic nerve section in newborn rats

1984 • 213 citations

Influences of neurotrophins on mammalian motoneurons in vivo

1993 • 205 citations

Cell death of motoneurons in the chick embryo spinal cord

1984 • 203 citations

Axotomy‐induced neuronal death during development

1992 • 198 citations

Retrograde transport of nerve growth factor (NGF) in motoneurons of developing rats: Assessment of potential neurotrophic effects

1988 • 151 citations

Cell death of motoneurons in the chick embryo spinal cord. VI. Reduction of naturally occurring cell death in the thoracolumbar column of terni by nerve growth factor

1982 • 147 citations

S100 is present in developing chicken neurons and schwann cell and promotes motor neuron survival in vivo

1992 • 145 citations

Motoneuron death and motor unit size during embryonic development of the rat

1984 • 135 citations

Effect of ciliary neurotrophic factor (CNTF) on motoneuron survival

1991 • 127 citations

Secretion and biological activities of heparin-binding growth-associated molecule. Neurite outgrowth-promoting and mitogenic actions of the recombinant and tissue-derived protein.

1992 • 118 citations

Cell death of motoneurons in the chick embryo spinal cord. V. Evidence on the role of cell death and neuromuscular function in the formation of specific peripheral connections

1981 • 117 citations

Neuronal death during development in the isthmo‐optic nucleus of the chick: Sustaining role of afferents from the tectum

1985 • 117 citations

Biological studies of a putative avian muscle‐derived neurotrophic factor that prevents naturally occurring motoneuron death in vivo

1993 • 112 citations

Cell death of axotomized motoneurones in neonatal rats, and its prevention by peripheral reinnervation.

1987 • 110 citations

Cell death of spinal motoneurons in the chick embryo following deafferentation: rescue effects of tissue extracts, soluble proteins, and neurotrophic agents

1994 • 110 citations

The dependence of motoneurons on their target muscle during postnatal development of the mouse

1990 • 104 citations

The effect of age on motor neurone death following axotomy in the mouse

1991 • 92 citations

Distribution of insulin-like growth factor peptides in the developing chick embryo

1990 • 86 citations

Insulin-like growth factor I and II and insulin-like growth factor binding protein-2 RNAs are expressed in adjacent tissues within rat embryonic and fetal limbs

1992 • 68 citations

The development of motoneurons in the embryonic spinal cord of the mouse mutant, muscular dysgenesis (): Survival, morphology, and biochemical differentiation

1986 • 65 citations

The influence of presumptive limb connective tissue on motoneuron axon guidance

1991 • 62 citations

Regulation of putative muscle-derived neurotrophic factors by muscle activity and innervation: in vivo and in vitro studies

1991 • 50 citations

Motoneuronal death during human fetal development

1987 • 46 citations

Abrupt loss of dependence of retinopetal neurons on their target cells, as shown by intraocular injections of kainate in chick embryos

1987 • 43 citations

Neuromuscular development following tetrodotoxin‐induced inactivity in mouse embryos

1990 • 25 citations

CHANGING PATTERNS OF AXONAL REACTION DURING NEURONAL DEVELOPMENT. A STUDY IN THE DEVELOPING CHICKEN NERVOUS SYSTEM

1977 • 11 citations

KGB Agents Disrupt Research Projects

1992 • 6 citations