Desensitization and recovery of muscarinic and histaminergic Ca2+ mobilization in 1321N1 astrocytoma cells

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

A model for receptor-regulated calcium entry

1986 • 2,535 citations

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

1982 • 2,255 citations

Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol

1983 • 1,104 citations

Calcium messenger system: an integrated view.

1984 • 916 citations

Micro-injection of inositol 1,3,4,5-tetrakisphosphate activates sea urchin eggs by a mechanism dependent on external Ca2+

1986 • 775 citations

The inositol tris/tetrakisphosphate pathway—demonstration of Ins(l,4,5)P3 3-kinase activity in animal tissues

1986 • 702 citations

Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes

1987 • 676 citations

Inositol trisphosphate and diacylglycerol as intracellular second messengers in liver

1985 • 419 citations

Phorbol ester inhibits phosphoinositide hydrolysis and calcium mobilization in cultured astrocytoma cells.

1985 • 274 citations

Muscarinic, alpha‐adrenergic and peptide receptors regulate the same calcium influx sites in the parotid gland.

1977 • 197 citations

Second messenger function of inositol 1,4,5-trisphosphate. Early changes in inositol phosphates, cytosolic Ca2+, and insulin release in carbamylcholine-stimulated RINm5F cells.

1986 • 149 citations

Relationships between phosphoinositide and calcium responses to muscarinic agonists in astrocytoma cells.

1984 • 125 citations

The role of extracellular Ca2+ in the response of the hepatocyte to Ca2+-dependent hormones.

1985 • 117 citations

Regulation of inositol trisphosphate accumulation by muscarinic cholinergic and H1-histamine receptors on human astrocytoma cells. Differential induction of desensitization by agonists

1987 • 98 citations

Guanine nucleotide regulation of agonist binding to muscarinic cholinergic receptors. Relation to efficacy of agonists for stimulation of phosphoinositide breakdown and Ca2+ mobilization

1985 • 96 citations

Pancreatic amylase secretion and cytoplasmic free calcium. Effects of ionomycin, phorbol dibutyrate and diacylglycerols alone and in combination

1985 • 95 citations

H1-histamine receptors on human astrocytoma cells.

1986 • 94 citations

Agonist-induced desensitization of muscarinic receptor-mediated calcium efflux without concomitant desensitization of phosphoinositide hydrolysis.

1985 • 81 citations

Regulation of Ion Channels By Inositol Trisphosphate and Diacylglycerol

1986 • 78 citations

Changes in cytosolic free calcium concentration in isolated rat parotid cells by cholinergic and β-adrenergic agonists

1985 • 76 citations

Cholecystokinin, carbachol, gastrin, histamine, and forskolin increase [Ca2+]i in gastric glands

1986 • 68 citations

Activation of muscarinic receptors in PC12 cells. Stimulation of Ca2+ influx and redistribution

1986 • 67 citations

Bradykinin-induced intracellular Ca2+ elevation in neuroblastoma × glioma hybrid NG108-15 cells; Relationship to the action of inositol phospholipids metabolites

1986 • 54 citations

Histamine activates H1-receptors to induce cytosolic free calcium transients in cultured vascular smooth muscle cells from rat aorta

1986 • 49 citations

Effect of atropine, ouabain, antimycin A, and A23187 on "trigger Ca2+ pool" in exocrine pancreas

1980 • 47 citations

Receptor-mediated inositol phosphate formation in relation to calcium mobilization: a comparison of two cell lines.

1987 • 43 citations

Heterologous desensitization of the cyclic AMP-independent glycogenolytic response in rat liver cells

1981 • 35 citations

Coupled sodium-calcium transport in cultured chick heart cells

1986 • 34 citations

Calcium-transporting systems of plasma membranes, with special attention to their regulation.

1984 • 28 citations

Receptor reserve in the calcium-dependent cyclic AMP response of astrocytoma cells to muscarinic receptor stimulation: demonstration by agonist-induced desensitization, receptor inactivation, and phorbol ester treatment.

1986 • 22 citations

SPECIFIC AND NON-SPECIFIC DESENSITIZATION OF GUINEA-PIG ILEAL SMOOTH MUSCLE

1984 • 21 citations