Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.

1987 • 2,266 citations

Signal sequences

1985 • 2,179 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

FIBRONECTIN AND ITS RECEPTORS

1988 • 1,336 citations

Cyclin synthesis drives the early embryonic cell cycle

1989 • 1,223 citations

Yeast RNA Polymerase II Genes: Isolation with Antibody Probes

1983 • 1,084 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

‘DNA Strider’: a ‘C’ program for the fast analysis of DNA and protein sequences on the Apple Macintosh family of computers

1988 • 1,010 citations

Comparison of the consensus sequence flanking translational start sites inDrosophilaand vertebrates

1987 • 966 citations

Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples.

1981 • 815 citations

Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein.

1986 • 645 citations

Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters

1988 • 597 citations

The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins.

1986 • 575 citations

A unique signature identifies a family of zinc‐dependent metallopeptidases

1989 • 453 citations

Comparison of human stromelysin and collagenase by cloning and sequence analysis

1986 • 443 citations

Electroblotting onto activated glass. High efficiency preparation of proteins from analytical sodium dodecyl sulfate-polyacrylamide gels for direct sequence analysis.

1986 • 440 citations

Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.

1986 • 339 citations

The structure of cell adhesion molecule uvomorulin. Insights into the molecular mechanism of Ca2+-dependent cell adhesion.

1987 • 304 citations

Genes for extracellular-matrix-degrading metalloproteinases and their inhibitor, TIMP, are expressed during early mammalian development.

1989 • 284 citations

Effects of actinomycin D on macromolecule synthesis and early development in sea urchin eggs

1963 • 280 citations

[58] Direct sequencing of denatured plasmid DNA

1987 • 246 citations

Amino acid sequence of rabbit kidney neutral endopeptidase 24.11 (enkephalinase) deduced from a complementary DNA.

1987 • 238 citations

Proteinases and extracellular remodeling

1989 • 224 citations

Structure and chromosomal localization of the functional intronless human JUN protooncogene.

1988 • 221 citations

α-Lactalbumin possesses a novel calcium binding loop

1986 • 216 citations

Human skin fibroblast procollagenase: mechanisms of activation by organomercurials and trypsin

1983 • 208 citations

The single-copy DNA sequence polymorphism of the sea urchin strongylocentrotus purpuratus

1978 • 181 citations

Structure-function relationships in the collagenase family member transin.

1988 • 169 citations

Competition hybridization by “pre-saturation” of HeLa cell DNA

1969 • 167 citations

[51] Gene isolation by screening λgt11 libraries with antibodies

1987 • 163 citations

DNA sequences, gene regulation and modular protein evolution in the Drosophila 68C glue gene cluster

1983 • 159 citations

A lineage-specific gene encoding a major matrix protein of the sea urchin embryo spicule

1987 • 154 citations

Gastrulation in the sea urchin embryo requires the deposition of crosslinked collagen within the extracellular matrix

1987 • 151 citations

Removal of the fertilization membrane of sea urchin embryos employing aminotriazole

1979 • 148 citations

Activation of sea urchin actin genes during embryogenesis

1986 • 131 citations

Comparison of the structures of carboxypeptidase A and thermolysin.

1977 • 129 citations

Accumulation in embryogenesis of five mRNAs enriched in the ectoderm of the sea urchin pluteus

1981 • 114 citations

Purification and Characterization of the Sea Urchin Embryo Hatching Enzyme

1989 • 92 citations

[22] Isolation and analysis of nuclear RNA

1987 • 91 citations

Isolation of the Oncogene and Epidermal Growth Factor-Induced Transin Gene: Complex Control in Rat Fibroblasts

1986 • 90 citations

Stage-specific expression of a homeo box-containing gene in the non-segmented sea urchin embryo.

1986 • 79 citations

Endo16, a lineage-specific protein of the sea urchin embryo, is first expressed just prior to gastrulation

1989 • 78 citations

Translation-level control of protein synthesis during early development

1965 • 76 citations

Structure and tissue-specific developmental expression of a sea urchin arylsulfatase gene

1989 • 65 citations

Maternal characteristics of hatching enzymes in hybrid sea urchin embryos

1969 • 53 citations

[62] Fast blots: Immobilization of DNA and RNA from cells

1987 • 53 citations

Structure of human hemopexin: O-glycosyl and N-glycosyl sites and unusual clustering of tryptophan residues.

1984 • 51 citations

Expression of a collagen gene in mesenchyme lineages of the Strongylocentrotus purpuratus embryo.

1988 • 45 citations

Unusual Pattern of Accumulation of mRNA Encoding EGF-Related Protein in Sea Urchin Embryos

1989 • 43 citations

A factor in sea urchin eggs inhibits transcription in isolated nuclei by sea urchin RNA polymerase III

1983 • 38 citations

Evidences of two different sets of histone genes active during embryogenesis of the sea urchin Paracentrotus lividus

1979 • 35 citations

[29] Hatching enzyme of the sea urchin Strongylocentrotus purpuratus

1976 • 35 citations

Coordinate accumulation of five transcripts in the primary mesenchyme during skeletogenesis in the sea urchin embryo

1988 • 32 citations

Purification and Characterization of Hatching Enzyme of Strongylocentrotus intermedius

1979 • 31 citations

Developmental Expression of Cell-Surface (Glyco)proteins Involved in Gastrulation and Spicule Formation in Sea Urchin Embryos

1985 • 14 citations

Chapter 3 Changing Populations of Reiterated DNA Transcripts During Early Echinoderm Development

1975 • 13 citations

The role of RNA polymerase initiation and elongation in control of total RNA and histone mRNA synthesis in sea urchin embryos

1984 • 7 citations