Applications of Artificial Neural Networks in Genome Research

Neural networks and physical systems with emergent collective computational abilities.

1982 • 18,281 citations

Parallel Distributed Processing: Explorations in the Microstructure of Cognition: Foundations

1986 • 15,232 citations

Parallel Distributed Processing

1986 • 14,631 citations

Self-Organization and Associative Memory

1989 • 8,952 citations

Atlas of protein sequence and structure

1965 • 4,462 citations

Untitled

1988 • 3,901 citations

Self-Organization and Associative Memory

1988 • 3,729 citations

Perceptrons: An Introduction to Computational Geometry

1969 • 3,322 citations

Advances in neural information processing systems 1

1989 • 3,021 citations

Prediction of Protein Secondary Structure at Better than 70% Accuracy

1993 • 2,958 citations

Phoneme recognition using time-delay neural networks

1989 • 2,556 citations

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

1987 • 2,333 citations

Compilation and analysis ofEscherichia colipromoter DNA sequences

1983 • 2,228 citations

Database of homology‐derived protein structures and the structural meaning of sequence alignment

1991 • 1,641 citations

Atlas of Protein Sequence and Structure, 1966.

1967 • 1,463 citations

Predicting the secondary structure of globular proteins using neural network models

1988 • 1,243 citations

Analysis of E.Coli Pormoter sequences

1987 • 1,029 citations

Recognition of protein coding regions in DNA sequences

1982 • 927 citations

Prediction of human mRNA donor and acceptor sites from the DNA sequence

1991 • 798 citations

Improvements in protein secondary structure prediction by an enhanced neural network

1990 • 708 citations

Characterization of translational initiation sites inE. coli

1982 • 673 citations

Locating protein-coding regions in human DNA sequences by a multiple sensor-neural network approach.

1991 • 665 citations

Use of the ‘Perceptron’ algorithm to distinguish translational initiation sites inE. coli

1982 • 660 citations

The U1 small nuclear RNA-protein complex selectively binds a 5′ splice site in vitro

1983 • 593 citations

The Human Genome Project: Past, Present, and Future

1990 • 527 citations

Protein secondary structure prediction with a neural network.

1989 • 506 citations

Escherichia colipromoter sequences predictin vitroRNA polymerase selectivity

1984 • 492 citations

Codon preference and its use in identifying protein coding regions in long DNA sequences

1982 • 476 citations

The codon preference plot: graphic analysis of protein coding sequences and prediction of gene expression

1984 • 381 citations

Learning internal representations by back-propagating errors

1986 • 345 citations

Scanning from an independently specified branch point defines the 3′ splice site of mammalian introns

1989 • 267 citations

Measurements of the effects that coding for a protein has on a DNA sequence and their use for finding genes

1984 • 254 citations

Identification of coding regions in genomic DNA sequences: an application of dynamic programming and neural networks

1993 • 215 citations

Sequence determinants of promoter activity

1982 • 145 citations

Neural network optimization forE.colipromoter prediction

1991 • 139 citations

A novel approach to prediction of the 3‐dimensional structures of protein backbones by neural networks

1990 • 135 citations

Determination of eukaryotic protein coding regions using neural networks and information theory

1992 • 119 citations

Predicting surface exposure of amino acids from protein sequence

1990 • 116 citations

Statistical characterization of nucleic acid sequence functional domains

1983 • 101 citations

Prediction of the disulfide-bonding state of cysteine in proteins

1990 • 101 citations

Training back-propagation neural networks to define and detect DNA-binding sites

1991 • 87 citations

Analysis of the occurrence of promoter-sites in DNA

1986 • 87 citations

Generalized protein tertiary structure recognition using associative memory hamiltonians

1991 • 78 citations

LEARNING AND RELEARNING

1959 • 70 citations

Predictlon of splice junctions in mRNA sequences

1985 • 60 citations

Escherichia colipromoters: neural networks develop distinct descriptions in learning to search for promoters of different spacing classes

1992 • 55 citations

Consensus methods for finding and ranking DNA binding sites

1989 • 53 citations

Neural Network Models for Promoter Recognition

1989 • 51 citations

Topological maps of protein sequences

1991 • 49 citations

G + C-rich tract in 5′ end of human introns

1992 • 46 citations

Statistical analysis of mammalian pre-mRNA splicing sites

1989 • 41 citations

Prediction of ATP-binding motifs: a comparison of a perceptron-type neural network and a consensus sequence method

1991 • 26 citations

Prediction of water binding sites on proteins by neural networks

1992 • 23 citations