Determination of the spectrum of beta-thalassemia genes in Spain by use of dot-blot analysis of amplified beta-globin DNA.

Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes

1986 • 1,863 citations

Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

1982 • 937 citations

Characterization of β-thalassaemia mutations using direct genomic sequencing of amplified single copy DNA

1987 • 514 citations

Nonrandom association of polymorphic restriction sites in the β-globin gene cluster

1982 • 408 citations

[49] DNA analysis in the diagnosis of hemoglobin disorders

1981 • 338 citations

DNA polymorphism and molecular pathology of the human globin gene clusters

1985 • 251 citations

Base substitution in an intervening sequence of a beta+-thalassemic human globin gene.

1981 • 236 citations

Polymorphism of DNA Sequence in the β-Globin Gene Region

1980 • 213 citations

beta zero thalassemia in Sardinia is caused by a nonsense mutation.

1981 • 192 citations

An intron nucleotide sequence variant in a cloned β⁺-thalassaemia globin gene

1981 • 124 citations

The molecular basis of beta-thalassemia in Lebanon: application to prenatal diagnosis

1987 • 99 citations

The peculiar spectrum of ?-thalassemia genes in Tunisia

1988 • 88 citations

β + Thalassaemia-Portuguese type: clinical, haematological and molecular studies of a newly defined form of β thalassaemia

1983 • 76 citations

The same beta-globin gene mutation is present on nine different beta-thalassemia chromosomes in a Sardinian population.

1987 • 58 citations

THE MOLECULAR BASIS FOR THE CLINICAL DIVERSITY OF $beta; THALASSAEMIA IN CYPRIOTS

1983 • 57 citations

?-thalassemia mutations in the Portuguese population

1988 • 45 citations

A β-thalassemia ledon abolishes the sameMstII site as the sickle mutation

1983 • 34 citations

Two cloned β thalassemia genes are associated with amber mutations at codon 39

1981 • 33 citations

A new nonsense mutation as the molecular basis for β° thalassaemia

1982 • 25 citations