The Development of Therapeutic Angiosuppression: Problems and Progress

Angiogenic Factors

1987 • 3,702 citations

Determinants of tumor blood flow: a review.

1988 • 1,362 citations

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

1990 • 1,308 citations

Structural Characterization and Biological Functions of Fibroblast Growth Factor

1987 • 1,299 citations

Anti-Angiogenesis

1972 • 1,167 citations

Important Advances in Oncology

1991 • 768 citations

Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides

1990 • 710 citations

Angiogenesis Inhibition and Tumor Regression Caused by Heparin or a Heparin Fragment in the Presence of Cortisone

1983 • 622 citations

Protamine is an inhibitor of angiogenesis

1982 • 582 citations

Endothelial proliferation in tumours and normal tissues: Continuous labelling studies

1984 • 562 citations

Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas

1991 • 485 citations

Tumor Angiogenesis: A Quantitative Method for Histologic Grading<xref ref-type="fn" rid="FN2">2</xref>

1972 • 418 citations

Suramin: an anticancer drug with a unique mechanism of action.

1989 • 370 citations

Inhibition of tumor angiogenesis mediated by cartilage.

1975 • 361 citations

Embryonic Origins and Assembly of Blood Vessels

1989 • 340 citations

Characterization of the receptors for vascular endothelial growth factor.

1990 • 310 citations

Important Advances in Oncology 1989

1990 • 304 citations

Tumor heterogeneity: biological implications and therapeutic consequences

1983 • 303 citations

Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin.

1986 • 270 citations

Angiostatic Steroids

1987 • 267 citations

Angiogenesis inhibition by minocycline.

1991 • 254 citations

Inhibition of angiogenesis and tumor growth in the brain. Suppression of endothelial cell turnover by penicillamine and the depletion of copper, an angiogenic cofactor.

1990 • 230 citations

Isolation of a nonmitogenic angiogenesis factor from wound fluid.

1982 • 219 citations

Expression of organ-specific antigens on capillary endothelial cells

1985 • 200 citations

A family of angiogenic peptides

1987 • 178 citations

Prolonged tumor dormancy by prevention of neovascularization in the vitreous.

1976 • 176 citations

Production a corpus luteum angiogenic factor responsible for proliferation of capillaries and neovascularization of the corpus luteum.

1978 • 174 citations

In situ detection of basic fibroblast growth factor by highly specific antibodies.

1990 • 168 citations

Vascular cells respond differentially to transforming growth factors beta 1 and beta 2 in vitro.

1991 • 137 citations

Tumor angiogenesis: the role of oncogenes and tumor suppressor genes.

1990 • 135 citations

Inhibition of Neovascularization by an Extract Derived from Vitreous

1977 • 132 citations

Autocrine transformation by chimeric signal peptide-basic fibroblast growth factor: reversal by suramin.

1990 • 123 citations

Studies on the Exchange of Fluids Between Host and Tumor. II. The Blood Flow of Hepatomas and Other Tumors In Rats and Mice<xref ref-type="fn" rid="FN1">2</xref>

1961 • 121 citations

Characterization of the receptor to vasculotropin on bovine adrenal cortex-derived capillary endothelial cells.

1990 • 120 citations

Vasculature as a Target for Tumour Therapy

2015 • 109 citations

Cellular and geometric control of tissue growth and mitotic instability

1976 • 99 citations

Inhibition of Tumor-Induced Angiogenesis by Sulfated Chitin Derivatives

1992 • 82 citations

Differential inhibition of various deoxyribonucleic and ribonucleic acid polymerases by suramin

1988 • 77 citations

Angiogenesis

1988 • 66 citations

Inhibition of basement membrane biosynthesis prevents angiogenesis.

1988 • 61 citations

Use of Suramin in Treatment of Prostatic Carcinoma Refractory to Conventional Hormonal Manipulation

1991 • 60 citations

The vasculature of experimental brain tumours

1984 • 59 citations

Tumor angiogenesis inhibition by prostaglandin synthetase inhibitors.

1986 • 53 citations

Neovascularization and tumor growth in the rabbit brain. A model for experimental studies of angiogenesis and the blood-brain barrier.

1988 • 49 citations

A pilot study of suramin in the treatment of metastatic renal cell carcinoma

1991 • 47 citations

Suramin inhibits proliferation of rat glioma cells and alters N‐cam cell surface expression

1990 • 45 citations

Affinity of fibroblast growth factors for β-cyclodextrin tetradecasulfate

1990 • 39 citations

Advances in neuro-oncology

1989 • 39 citations

The Angiogenic Properties of the Rat Vibrissa Hair Follicle Associate with the Bulb

1988 • 38 citations

Adjuvant therapy—Theory, practice, and potential. The james ewing lecture

1976 • 38 citations

Angiogenesis. State of the art

1988 • 31 citations

Molecular and cellular mechanisms of angiogenesis.

1990 • 30 citations

Suramin inhibits binding and degradation of platelet-derived growth factor in arterial smooth muscle cells but does not interfere with autocrine stimulation of DNA synthesis

1989 • 27 citations

Rapid in situ cellular kinetics of intracerebral tumor angiogenesis using a monoclonal antibody to bromodeoxyuridine

1989 • 26 citations

Proliferative potential of vascular components in human glioblastoma multiforme

1987 • 26 citations

Statin immunolocalization in human brain tumors. Detection of noncycling cells using a novel marker of cell quiescence

1991 • 24 citations

Rapid In Situ Cellular Kinetics of Intracerebral Tumor Angiogenesis Using a Monoclonal Antibody to Bromodeoxyuridine

1989 • 21 citations

Pharmacokinetics.Selectivity of action related to physicochemical properties and kinetic patterns of anticancer drugs

1977 • 16 citations

Potentiation of angiostatic steroids by a synthetic inhibitor of arylsulfatase.

1988 • 16 citations

The Role of New Vessels and Macrophages in the Development and Resolution of Edema Following a Cortical Freeze Lesion in the Mouse

1987 • 9 citations

Prophylactic antiangiogenic tumor treatment.

1989 • 5 citations

New Pathways in Science and Technology

1985 • 1 citations