Friedreich ataxia in Louisiana Acadians: demonstration of a founder effect by analysis of microsatellite-generated extended haplotypes.

Informativeness of human (dC-dA)n · (dG-dT)n polymorphisms

1990 • 1,371 citations

FRIEDREICH'S ATAXIA: A CLINICAL AND GENETIC STUDY OF 90 FAMILIES WITH AN ANALYSIS OF EARLY DIAGNOSTIC CRITERIA AND INTRAFAMILIAL CLUSTERING OF CLINICAL FEATURES

1981 • 903 citations

Spontaneous mutation rates to new length alleles at tandem-repetitive hypervariable loci in human DNA

1988 • 773 citations

Towards construction of a high resolution map of the mouse genome using PCR-analysed microsatellites

1990 • 475 citations

Clinical Description and Roentgenologic Evaluation of Patients with Friedreich's Ataxia

1976 • 376 citations

Mapping of mutation causing Friedreich's ataxia to human chromosome 9

1988 • 307 citations

The polydeoxyadenylate tract of Alu repetitive elements is polymorphic in the human genome.

1990 • 254 citations

Mapping Complex Genetic Traits in Humans: New Methods Using a Complete RFLP Linkage Map

1986 • 187 citations

Confirmation of linkage of Friedreich ataxia to chromosome 9 and identification of a new closely linked marker

1989 • 74 citations

Genetic homogeneity at the Friedreich ataxia locus on chromosome 9.

1989 • 71 citations

Genealogical analysis of cystic fibrosis families and chromosome 7q RFLP haplotypes in the Hutterite Brethren.

1989 • 63 citations

Nonradioactive assay for new microsatellite polymorphisms at the 5' end of the dystrophin gene, and estimation of intragenic recombination.

1991 • 61 citations

Additional polymorphisms at marker loci D9S5 and D9S15 generate extended haplotypes in linkage disequilibrium with Friedreich ataxia.

1990 • 56 citations

The Friedreich ataxia gene is assigned to chromosome 9q13-q21 by mapping of tightly linked markers and shows linkage disequilibrium with D9S15.

1990 • 54 citations

Recessive ataxia in Acadians and “Cajuns”

1984 • 51 citations

Vector-Alu PCR: a rapid step in mapping cosmids and YACs

1990 • 50 citations

Linkage disequilibrium in the human insulin/insulin-like growth factor II region of human chromosome II.

1988 • 48 citations

Friedreich ataxia in Italian families: genetic homogeneity and linkage disequilibrium with the marker loci D9S5 and D9S15.

1990 • 44 citations

Identification of a hypervariable microsatellite polymorphism within D9S15 tightly linked to Friedreich's ataxia

1990 • 40 citations

“Acadian” and “classical” forms of Friedreich ataxia are most probably caused by mutations at the same locus

1989 • 31 citations

Cystic fibrosis mutations in North American populations of French ancestry: analysis of Quebec French-Canadian and Louisiana Acadian families.

1990 • 29 citations

Physical mapping of two loci (D9S5 and D9S15) tightly linked to Friedreich ataxia locus (FRDA) and identification of nearby CpG islands by pulse-field gel electrophoresis

1991 • 22 citations

Identification of CpG islands in a physical map encompassing the Friedreich's ataxia locus

1991 • 21 citations

A human single-copy DNA probe (DR 47) detects a Taq I RFLP on chromosome 9 (D9S5)

1987 • 8 citations