The transmembrane domains of the nicotinic acetylcholine receptor contain alpha-helical and beta structures.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

Examination of the secondary structure of proteins by deconvolved FTIR spectra

1986 • 2,865 citations

Vibrational Spectroscopy and Conformation of Peptides, Polypeptides, and Proteins

1986 • 2,761 citations

Nicotinic Acetylcholine Receptor an 9 Å Resolution

1993 • 822 citations

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

1988 • 798 citations

Structural homology of Torpedo californica acetylcholine receptor subunits

1983 • 798 citations

[13] Resolution-enhanced fourier transform infrared spectroscopy of enzymes

1986 • 690 citations

Acetylcholine Receptor Channel Structure Probed in Cysteine-Substitution Mutants

1992 • 668 citations

Secondary structure and dosage of soluble and membrane proteins by attenuated total reflection Fourier‐transform infrared spectroscopy on hydrated films

1990 • 526 citations

Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor.

1984 • 513 citations

Nucleotide and deduced amino acid sequences of Torpedo californica acetylcholine receptor gamma subunit.

1983 • 412 citations

Location of a δ-subunit region determining ion transport through the acetylcholine receptor channel

1986 • 315 citations

The ion channel of the nicotinic acetylcholine receptor is formed by the homologous helices M II of the receptor subunits

1986 • 313 citations

Infrared spectra and resonance interaction of amide‐I vibration of the antiparallel‐chain pleated sheet

1976 • 311 citations

An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor

1990 • 275 citations

Infrared spectra and resonance interactions of amide‐I and II vibrations of α‐helix

1976 • 269 citations

Neurotransmitter action: Opening of ligand-gated ion channels

1993 • 267 citations

Polarized infrared spectroscopy of oriented purple membrane

1979 • 241 citations

The noncompetitive blocker [3H]chlorpromazine labels three amino acids of the acetylcholine receptor gamma subunit: implications for the alpha-helical organization of regions MII and for the structure of the ion channel.

1990 • 186 citations

Immunofluorescence localization at the mammalian neuromuscular junction of the Mr 43,000 protein of Torpedo postsynaptic membranes.

1981 • 144 citations

Membranes Rich in Acetylcholine Receptor: Characterization and Reconstitution to Excitable Membranes from Exogenous Lipids

1978 • 132 citations

Consequences of alkaline treatment for the ultrastructure of the acetylcholine-receptor-rich membranes from Torpedo marmorata electric organ.

1981 • 118 citations

Conformational analysis of phosphatidylethanolamine in multilayers by infrared dichroism

1975 • 91 citations

Infrared Spectra and the Chain Organization of Erythrocyte Membranes

1968 • 69 citations

Preparation of right-side-out, acetylcholine receptor enriched intact vesicles from Torpedo californica electroplaque membranes

1979 • 67 citations

Secondary structure and temperature behavior of the acetylcholine receptor by Fourier transform infrared spectroscopy

1993 • 62 citations

The selectivity filter of a ligand‐gated ion channel

1989 • 41 citations

αDL and πDL Helices of alternating poly-γ-benzyl-d-l-glutamate

1975 • 40 citations