Fetal Alcohol Effects: Rat Model of Alcohol Exposure during the Brain Growth Spurt

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1986 • 3,586 citations

RECOGNITION OF THE FETAL ALCOHOL SYNDROME IN EARLY INFANCY

1973 • 2,780 citations

Comparative aspects of the brain growth spurt

1979 • 2,491 citations

PATTERN OF MALFORMATION IN OFFSPRING OF CHRONIC ALCOHOLIC MOTHERS

1973 • 2,156 citations

Quantitative growth and development of human brain

1973 • 1,439 citations

The Fetal Alcohol Syndrome

1978 • 1,371 citations

SALMONELLAS IN MEAT.

1964 • 1,158 citations

Hypoplasia of Cerebellar Vermal Lobules VI and VII in Autism

1988 • 1,039 citations

Teratogenic Effects of Alcohol in Humans and Laboratory Animals

1980 • 664 citations

Fetal Alcohol Syndrome: Embryogenesis in a Mouse Model

1981 • 630 citations

Alcohol‐Induced Neuronal Loss in Developing Rats: Increased Brain Damage with Binge Exposure

1990 • 558 citations

Moderate Prenatal Alcohol Exposure: Effects on Child IQ and Learning Problems at Age 7 1/2 Years

1990 • 549 citations

Alcohol and Brain Development

1987 • 525 citations

Prenatal ethanol exposure permanently reduces the number of pyramidal neurons in rat hippocampus

1981 • 384 citations

Effects of Alcohol on the Generation and Migration of Cerebral Cortical Neurons

1986 • 375 citations

Prenatal alcohol exposure: Comparability of effects in humans and animal models

1990 • 371 citations

The fetal alcohol syndrome in mice: An animal model

1977 • 360 citations

THE EFFECTS OF MODERATE ALCOHOL CONSUMPTION DURING PREGNANCY ON FETAL GROWTH AND MORPHOGENESIS

1977 • 322 citations

Some teratogenic properties of ethanol and acetaldehyde in C57BL/6J mice: Implications for the study of the fetal alcohol syndrome

1983 • 309 citations

Numbers of neurons and glia in mature rat somatosensory cortex: Effects of prenatal exposure to ethanol

1990 • 277 citations

The effect of ethanol chronically administered to preweanling rats on cerebellar development: A morphological study

1977 • 275 citations

A Revised Conservative Estimate of the Incidence of FAS and its Economic Impact

1991 • 260 citations

Anomalous Brain Morphology on Magnetic Resonance Images in Williams Syndrome and Down Syndrome

1990 • 242 citations

Permanent neuronal deficits in rats exposed to alcohol during the brain growth spurt

1991 • 239 citations

Maternal Alcohol Use during Breast-Feeding and Infant Mental and Motor Development at One Year

1989 • 235 citations

Delay in brain growth induced by alcohol in artificially reared rat pups

1984 • 234 citations

A single day of alcohol exposure during the brain growth spurt induces brain weight restriction and cerebellar Purkinje cell loss

1990 • 226 citations

Prenatal ethanol exposure in mice: Teratogenic effects

1979 • 219 citations

A Hypothetical Mechanism for Fetal Alcohol Syndrome Involving Ethanol Inhibition of Retinoic Acid Synthesis at the Alcohol Dehydrogenase Step

1991 • 197 citations

Impaired Brain Growth in Neonatal Rats Exposed to Ethanol

1980 • 190 citations

Neuropsychological Deficits in Fetal Alcohol Syndrome and Fetal Alcohol Effects

1990 • 186 citations

Blood alcohol concentration and severity of microencephaly in neonatal rats depend on the pattern of alcohol administration

1988 • 179 citations

Fetal Alcohol Syndrome: Current Status of Pathogenesis

1990 • 177 citations

Long term potentiation in the hippocampus: mechanisms of initiation and modulation by neurotransmitters

1985 • 174 citations

Effect of Prenatal Exposure to Ethanol on the Development of Cerebral Cortex: I. Neuronal Generation

1988 • 173 citations

Ethanol‐Induced Malformations in Mice

1977 • 170 citations

Effect of Prenatal Exposure to Ethanol on the Cell Cycle Kinetics and Growth Fraction in the Proliferative Zones of Fetal Rat Cerebral Cortex

1991 • 169 citations

Patterns of alcohol consumption and fetal development.

1983 • 168 citations

Cell Population Depletion Associated with Fetal Alcohol Brain Damage: Mechanisms of BAC‐Dependent Cell Loss

1990 • 165 citations

The fetal alcohol syndrome in mice: Maternal variables

1980 • 160 citations

Differential neuronal loss following early postnatal alcohol exposure

1989 • 157 citations

Neonatal Neurobehavioral Characteristics as Correlates of Maternal Alcohol Use during Gestation

1985 • 153 citations

Effect of prenatal exposure to alcohol on the distribution and time of origin of corticospinal neurons in the rat

1987 • 147 citations

Impaired spatial navigation in adult female but not adult male rats exposed to alcohol during the brain growth spurt

1988 • 146 citations

Blood alcohol concentration and microencephaly: A dose‐response study in the neonatal rat

1988 • 139 citations

Effects of prenatal exposure to ethanol on neocortical development: II. Cell proliferation in the ventricular and subventricular zones of the rat

1989 • 138 citations

Brain malformations in prenatal mice following acute maternal ethanol administration

1984 • 129 citations

The Long‐Term Behavioral Effects of Prenatal Alcohol Exposure in Rats

1990 • 126 citations

Long-term deficits in cerebellar growth and rotarod performance of rats following “binge-like” alcohol exposure during the neonatal brain growth spurt

1991 • 125 citations

Fetal alcohol-induced brain damage and the problem of determining temporal vulnerability: a review.

1987 • 123 citations

Early postnatal alcohol exposure that produces high blood alcohol levels impairs development of spatial navigation learning

1987 • 118 citations

Prenatal ethanol exposure decreases hippocampal NMDA-sensitive [3H]-Glutamate binding site density in 45-day-old rats

1991 • 117 citations

Discrimination learning alters the distribution of protein kinase C in the hippocampus of rats

1990 • 114 citations

Prenatal exposure to ethanol decreases physiological plasticity in the hippocampus of the adult rat

1988 • 112 citations

Prenatal ethanol exposure during the last third of gestation in rat reduces hippocampal NMDA agonist binding site density in 45-day-old offspring

1992 • 109 citations

Effect of prenatal exposure to ethanol on the activity of the hypothalamic-pituitary-adrenal axis of the offspring: Importance of the time of exposure to ethanol and possible modulating mechanisms

1990 • 107 citations

Pituitary‐Adrenal Responses to Morphine and Footshock Stress Are Enhanced following Prenatal Alcohol Exposure

1986 • 102 citations

Immunocytochemical Studies of Astrocytes in Normal Development and Disease

1982 • 101 citations

Alterations in Gait Following Ethanol Exposure During the Brain Growth Spurt in Rats

1990 • 99 citations

Hypothesis: Prenatal Ethanol‐Induced Birth Defects and Retinoic Acid

1991 • 99 citations

Effects of alcohol exposure during different periods of development: changes in hippocampal mossy fibers

1985 • 98 citations

Physical anomalies and developmental delays in nonhuman primate infants exposed to weekly doses of ethanol during gestation

1988 • 95 citations

Fetal Alcohol Syndrome and Fetal Alcohol Effects

1985 • 89 citations

Teratogenic Effects of Alcohol on Brain Development

1990 • 88 citations

Natural loss of Purkinje cells during development and increased loss with alcohol

1985 • 87 citations

Determination of the proximate teratogen of the mouse fetal alcohol syndrome

1984 • 86 citations

Prenatal ethanol exposure decreases hippocampal 3H-glutamate binding in 45-day-old rats

1988 • 85 citations

Historical factors in the development of ETOH-conditioned place preference

1992 • 83 citations

Intragastric Intubation of Alcohol During Postnatal Development of Rats Results in Selective Cell Loss in the Cerebellum

1993 • 81 citations

Surgeon general's advisory on alcohol and pregnancy

1981 • 81 citations

Neonatal ethanol exposure: Functional alterations associated with cerebellar growth retardation

1990 • 80 citations

Reduction of Alcohol Consumption During Pregnancy with Benefits to the Newborn

1980 • 78 citations

Prenatal exposure to ethanol decreases the sensitivity of the adult rat hippocampus to N-methyl-D-aspartate

1989 • 77 citations

Neuroanatomic and Neurochemical Abnormalities in Non‐human Primate Infants Exposed to Weekly Doses of Ethanol during Gestation

1990 • 76 citations

Manipulating peak blood alcohol concentrations in neonatal rats: review of an animal model for alcohol-related developmental effects.

1989 • 74 citations

Microencephaly and hyperactivity in adult rats can be induced by neonatal exposure to high blood alcohol concentrations

1987 • 71 citations

Permanent hippocampal mossy fiber hyperdevelopment following prenatal ethanol exposure.

1983 • 69 citations

The effect of volume and duration of prenatal ethanol exposure on neonatal physical and behavioral development.

1986 • 69 citations

Strategies for prevention of fetal alcohol effects.

1981 • 68 citations

Prenatal ethanol alters gait in rats

1988 • 67 citations

Perspectives on the Pathophysiology of Fetal Alcohol Syndrome

1990 • 67 citations

Fetal Alcohol Exposure: Cellular Toxicity and Molecular Events Involved in Toxicity

1990 • 66 citations

Behavioral and neuroanatomical effects of prenatal, postnatal, or combined exposure to ethanol in weanling rats.

1990 • 63 citations

Genetic influences on brain growth restriction induced by development exposure to alcohol.

1989 • 54 citations

Alcohol consumption during pregnancy among Southern city women

1985 • 54 citations

Maternal Genetic Effects on Ethanol Teratogenesis and Dominance of Relative Embryonic Resistance to Malformations

1990 • 53 citations

Behavioral and neuroanatomical effects of prenatal, postnatal, or combined exposure to ethanol in weanling rats.

1990 • 51 citations

Acute and long-term neuronal deficits in the rat olfactory bulb following alcohol exposure during the brain growth spurt

1991 • 46 citations

Ethanol Teratogenesis in Selectively Bred Long‐Sleep and Short‐Sleep Mice: A Comparison to Inbred C57BL/6J Mice

1989 • 45 citations

Molecular Changes Associated with Ethanol‐Induced Growth Suppression in the Chick Embryo

1990 • 44 citations

Influence of ethanol on neuronal and synaptic maturation in the central nervous system—Morphological investigations

1988 • 42 citations

The effect of in utero ethanol exposure on hippocampal mossy fibers: an HRP study

1984 • 39 citations

Alterations in sensorimotor development: Relationship to postnatal alcohol exposure

1987 • 37 citations

Brain growth deficits following a single day of alcohol exposure in the neonatal rat

1989 • 37 citations

Passive avoidance performance following neonatal alcohol exposure

1990 • 34 citations

Ethanol teratogenesis in mice selected for differences in alcohol sensitivity

1988 • 28 citations

Experimental Teratology of Ethanol

1988 • 19 citations

Prenatal Ethanol Exposure Decreases Hippocampal Mossy Fiber Zinc in 45‐Day‐Old Rats

1989 • 17 citations

Interactive Effects of Ethanol and Caffeine on Rat Fetal Hepatocyte Replication and EGF Receptor Expression

1991 • 12 citations

Fetal Alcohol Syndrome

1981 • 8 citations

Deleted Work

1955 • 0 citations