Experimental Teratology of Ethanol

Ciba foundation symposium

1964 • 2,217 citations

PATTERN OF MALFORMATION IN OFFSPRING OF CHRONIC ALCOHOLIC MOTHERS

1973 • 2,156 citations

The mouse; its reproduction and development

1968 • 1,290 citations

Environment and birth defects

1975 • 724 citations

Teratogenic Effects of Alcohol in Humans and Laboratory Animals

1980 • 664 citations

Fetal Alcohol Syndrome: Embryogenesis in a Mouse Model

1981 • 630 citations

New conceptions in the pathogenesis of sciatic pain

1927 • 577 citations

Chemically induced birth defects

1986 • 515 citations

High Blood Acetaldehyde Levels after Ethanol Administration

1975 • 514 citations

The fetal alcohol syndrome in mice: An animal model

1977 • 360 citations

Fetal Alcohol Syndrome and Fetal Alcohol Effects

1984 • 332 citations

Some teratogenic properties of ethanol and acetaldehyde in C57BL/6J mice: Implications for the study of the fetal alcohol syndrome

1983 • 309 citations

Alcohol and Aldehyde Metabolizing Systems

1977 • 303 citations

Sequence of developmental alterations following acute ethanol exposure in mice: Craniofacial features of the fetal alcohol syndrome

1983 • 245 citations

1986 UPDATE: The Feeding of Ethanol in Liquid Diets

1986 • 239 citations

Prenatal ethanol exposure in mice: Teratogenic effects

1979 • 219 citations

The effects of drinking on offspring: an historical survey of the American and British literature.

1975 • 213 citations

Skeletal deviations in rats: Malformations or variations?

1973 • 209 citations

Effects of prenatal alcohol exposure on growth and development in rats.

1978 • 204 citations

Ethanol Embryotoxicity: Direct Effects on Mammalian Embryos in Vitro

1979 • 203 citations

Maternal Ethanol Exposure Induces Transient Impairment of Umbilical Circulation and Fetal Hypoxia in Monkeys

1982 • 199 citations

Teratogenic effects of ethyl alcohol administered to pregnant mice

1976 • 177 citations

Ethanol‐Induced Malformations in Mice

1977 • 170 citations

Psychopharmacology of alcohol

1980 • 170 citations

The fetal alcohol syndrome in mice: Maternal variables

1980 • 160 citations

Adverse effects of maternal alcohol consumption on pregnancy and foetal growth in rats

1975 • 154 citations

Effects of Ethanol and Maternal Nutritional Status on Fetal Development

1985 • 154 citations

Blood alcohol concentration: A critical factor for producing fetal alcohol effects

1986 • 152 citations

Effects of ethanol on pregnant rats and their offspring

1978 • 140 citations

Chemically induced birth defects

1986 • 130 citations

The teratogenic effect of acetaldehyde: implications for the study of the fetal alcohol syndrome.

1979 • 127 citations

Hypoxia and drug metabolism

1981 • 122 citations

Developmental changes in alcohol-dehydrogenase activity in rat and guinea-pig liver

1967 • 121 citations

Interaction of ethanol and nutrition during gestation: influence on maternal and offspring development in the rat.

1981 • 109 citations

Consumption of alcohol during pregnancy: a review of effects on growth and development of offspring.

1982 • 107 citations

Induction of dominant lethal mutation in male mice by ethyl alcohol

1975 • 101 citations

The Effects of Chronic and Acute Alcohol Administration on Fetal Development in the Rat

1979 • 95 citations

Fetal alcohol syndrome: A new primate model for binge drinking and its relevance to human ethanol teratogenesis

1982 • 92 citations

Sporadic Malformations in Laboratory Animals and Their Influence on Drug Testing

1972 • 89 citations

Nutritional issues in perinatal alcohol exposure.

1984 • 89 citations

Disulfiram as a Tool in the Studies on the Metabolism of Acetaldehyde in Rats

1976 • 89 citations

Placental blood flow in rats fed alcohol before and during gestation

1981 • 88 citations

Placental and Foetal Metabolism of Acetaldehyde in Rat I. Contents of Ethanol and Acetaldehyde in Placenta and Foetus of the Pregnant Rat during Ethanol Oxidation

1975 • 88 citations

Alcohol produces spasms of human umbilical blood vessels: Relationship to fetal alcohol syndrome (FAS)

1982 • 87 citations

Determination of the proximate teratogen of the mouse fetal alcohol syndrome

1984 • 86 citations

An Animal Model of the Fetal Alcohol Syndrome in Beagles

1980 • 82 citations

Teratogenic potential of ethanol in mice, rats and rabbits

1978 • 81 citations

The Effect of Ethanol and Acetaldehyde on DNA Synthesis in Growing Cells and on Fetal Development in the Rat

1981 • 81 citations

Placental transport of alcohol and its effect on maternal and fetal acid-base balance

1975 • 80 citations

Placental Transfer and Tissue Distribution of Ethanol-1-¹⁴C; A Radioautographic Study in Monkeys and Hamsters

1972 • 71 citations

Ethanol teratogenicity in mice: A light microscopic study

1982 • 68 citations

Ribosomal proteins synthesis in the fetal and neonatal rat brain as influenced by maternal ethanol consumption.

1975 • 67 citations

Fetal alcohol syndrome: inhibition of placental zinc transport as a potential mechanism for fetal growth retardation in the rat.

1982 • 67 citations

The effect of maternal alcohol consumption on the viability and visceral development of the newborn rat.

1977 • 65 citations

Teratogenicity of acetaldehyde : Relevance to the fatal alcohol syndrome

1983 • 64 citations

Inhibition of placental valine uptake after acute and chronic maternal ethanol consumption.

1981 • 64 citations

Effect of maternal ethanol consumption on foetal and neonatal rat hepatic protein synthesis

1976 • 63 citations

Further development of rodent whole embryo culture: Solvent toxicity and water insoluble compound delivery system

1984 • 62 citations

Neuromotor development and response inhibition following prenatal ethanol exposure.

1982 • 62 citations

Effect of ethanol feeding during pregnancy on placental transfer of alpha-aminoisobutyric acid in the rat

1981 • 62 citations

Effect of Ethanol and Ethanol‐Induced Hypothermia on Protein Synthesis in Pregnant and Fetal Rats

1980 • 60 citations

Determination of the proximate teratogen of the mouse fetal alcohol syndrome

1984 • 58 citations

Effect of maternal ethanol administration on physical growth of the offspring in rats.

1979 • 57 citations

The fetal alcohol syndrome: symptoms and pathogenesis.

1978 • 56 citations

Effects of pyrazole and 3-amino-1,2,4-triazole on methanol and ethanol metabolism by the rat

1973 • 55 citations

Paternal effects of ethanol in the long‐Evans rat

1982 • 54 citations

Metabolism of ethanol and acetaldehyde in intact rats during pregnancy

1974 • 53 citations

The Effects of Maternal Ethanol Consumption in the Rat on the Development of their Offspring

1979 • 52 citations

Rat Placental Protein Synthesis and Peptide Hormone Secretion in Relation to Malnutrition from Protein Deficiency or Alcohol Administration

1979 • 51 citations

Effect of ethanol upon uterine activity and fetal acid-base state of the rhesus monkey

1971 • 51 citations

Teratogenic effects of acetaldehyde in the rat

1982 • 49 citations

Ethanol‐Induced Intrauterine Growth Retardation: Correlation with Placental Glucose Transfer

1986 • 49 citations

Effect of acetaldehyde on the neuroepithelium of early mouse embryos.

1981 • 49 citations

The effects of ethanol on rat embryos developing in vitro

1982 • 47 citations

Selective fetal malnutrition: The effect of ethanol and acetaldehyde upon uptake of alpha amino isobutyric acid by human placenta

1981 • 45 citations

The effect of paternal alcohol consumption on fetal development in mice

1982 • 45 citations

Considerations for the design, implementation, and interpretation of animal models of fetal alcohol effects.

1984 • 45 citations

Prenatal Alcohol Exposure: Abnormalities in Placental Growth and Fetal Amino Acid Uptake in the Rat

1985 • 44 citations

Prenatal effects of alcohol on growth: a brief overview.

1985 • 43 citations

Fetal Alcohol Syndrome in Sinclair(S‐l) Miniature Swine

1980 • 43 citations

Ethanol-induced prenatal growth deficiency: changes in fetal body composition.

1979 • 40 citations

Ethanol‐Associated Selective Fetal Malnutrition: A Contributing Factor in the Fetal Alcohol Syndrome

1982 • 38 citations

Effects of ethanol on the primitive streak stage mouse embryo

1984 • 37 citations

The differential transplacental effects of ethanol in four mouse strains.

1980 • 37 citations

Experimental studies on the influence of male alcoholism on fetal development

1982 • 37 citations

Organ growth and cellular development in ethanol-exposed rats

1986 • 37 citations

Selective Fetal Malnutrition: the Effect of in Vivo Ethanol Exposure upon in Vitro Placental Uptake of Amino Acids in the Non-Human Primate

1983 • 37 citations

Effect of ethanol upon placental uptake of amino acids.

1981 • 37 citations

Interaction Between Zinc Deprivation and Acute Ethanol Intoxication During Pregnancy in Rats

1981 • 36 citations

Short-term and long-term ethanol administration inhibits the placental uptake and transport of valine in rats.

1981 • 35 citations

Growth, Enzymes and Hormonal Changes in Offspring of Alcohol‐Fed Rats

1984 • 34 citations

Nutritional Deficiencies and Excesses

1977 • 34 citations

Renal anomalies in mice prenatally exposed to ethanol.

1979 • 34 citations

Fetal malnutrition: a possible cause of the fetal alcohol syndrome.

1981 • 34 citations

Placental and Foetal Metabolism of Acetaldehyde in Rat II. Studies on Metabolism of Acetaldehyde in the Isolated Placenta and Foetus

1975 • 34 citations

Ethanol teratogenicity in mice: An electron microscopic study

1984 • 32 citations

Effect of litter size on the physical growth and maturation of the offspring of rats given alcohol during gestation.

1980 • 31 citations

Polydactyly and polysyndactyly induced by prenatal exposure to ethanol

1981 • 30 citations

Heat- and Alcohol-Induced Neural Tube Defects: Interactions with Folate in a Golden Hamster Model

1985 • 30 citations

Growth deficits in rats exposed to alcohol in utero.

1980 • 30 citations

Tetratological evaluation of mouse fetuses after paternal alcohol ingestion.

1981 • 30 citations

Effects of beer, wine, whiskey, and ethanol on pregnant rats and their offspring

1981 • 29 citations

Mechanisms of Alcohol Damage in Utero

1985 • 29 citations

Ethanol Ingestion during Pregnancy: Effects on Pregnant Rats and Their Offspring

1982 • 28 citations

Exencephaly and axial skeletal dysmorphogenesis induced by acute doses of ethanol in mouse fetuses

1985 • 28 citations

Is Moderate Ethanol Consumption Teratogenic in the Rat?

1978 • 28 citations

A subhuman primate model for fetal alcohol syndrome research.

1981 • 28 citations

Selective Fetal Malnutrition: Effect of Acute and Chronic Ethanol Exposure upon Rat Placental Na, K‐ATPase Activity

1986 • 27 citations

The effects of ethanol on embryonic actin: A possible role in teratogenesis

1986 • 27 citations

Inhibition of Mouse Sperm Capacitation by Ethanol

1982 • 27 citations

Prenatal alcohol exposure: current issues and the status of animal research.

1981 • 27 citations

The effects of prenatal ethanol in cynomolgus monkeys

1984 • 26 citations

Effects of acute doses of ethanol on pre- and postnatal development in the mouse

1984 • 26 citations

Growth-Depressing Effects of Alcohol and Nicotine in Two Strains of Rats

1985 • 25 citations

The effect of ethanol feeding on zinc balance and tissue zinc levels in rats maintained on zinc-deficient diets.

1982 • 25 citations

Ethanol and acetaldehyde metabolism in the pregnant mouse

1977 • 25 citations

The effects of high dose sporadic (binge) alcohol intake in mice

1984 • 23 citations

The passage to the foetus and liquor amnii of ethanol administered orally to the pregnant mouse.

1981 • 23 citations

Ethanol kinetics during pregnancy. study in ewes and their fetuses

1982 • 22 citations

Alcohol induced cardiac malformations in the rat.

1984 • 22 citations

Cardiac muscle development in mice exposed to ethanol in utero

1984 • 21 citations

Effects of Acute Ethanol Exposure upon In Vivo Leucine Uptake and Protein Synthesis in the Fetal Rat

1981 • 21 citations

Developmental patterns of alcohol dehydrogenase and aldehyde dehydrogenases in homogenates and subcellular fractions of rat liver

1979 • 21 citations

Measures of Alcohol Damage in vitro in the Pigtailed Macaque ( Macaca nemestrina )

1984 • 21 citations

Teratogenic and reproductive effects of ethanol in Long‐Evans rats

1982 • 21 citations

Magnesium and zinc deficiency and growth retardation in offspring of alcoholic rats.

1982 • 20 citations

The role of maternal diet in the developmental toxicology of ethanol

1984 • 20 citations

Autoradiographic studies on the distribution of 14C-2-ethanol and its non-volatile metabolites in the pregnant mouse.

1974 • 20 citations

Differential pharmacokinetics for oral and intraperitoneal administration of ethanol to the pregnant guinea pig

1985 • 20 citations

Maternal, Fetal, and Neonatal Elimination of Ethanol in Nonhuman Primates

1983 • 19 citations

Effect of acetaldehyde on skeletogenesis in rats

1984 • 18 citations

Method of ethanol administration as a confounding factor in studies of fetal alcohol syndrome

1982 • 17 citations

TERATOGENIC EFFECT OF MATERNAL ALCOHOL CONSUMPTION ON THE MOUSE FETUS

1980 • 17 citations

Interactions Between Trace Elements and Alcohol in Rats

1984 • 15 citations

Experimental Production of Growth Retardation in The Sheep Fetus after Exposure to Alcohol

1980 • 14 citations

Influence of pyrazole, an inhibitor of alcohol dehydrogenase on the prenatal toxicity of ethanol in the rat.

1979 • 14 citations

Alcohol-induced alterations in calcium metabolism in the pregnant rat

1982 • 13 citations

Thiamin depletion after ethanol and acetaldehyde administration to rabbits.

1983 • 13 citations

Lack of prenatal effects of maternal ethanol consumption in CD-1 MICE

1979 • 12 citations

Fetal Alcohol Syndrome: An Examination of Craniofacial Dysmorphology in Macaca nemestrina

1985 • 12 citations

Acute embryopathic effects of ethanol in the long‐evans rat

1983 • 11 citations

Effect of maternal alcohol consumption on pre- and post-natal muscle development of mice.

1984 • 11 citations

Compensatory embryonic development in the rat following maternal treatment with ethanol.

1980 • 11 citations

Fetal alcohol syndrome: neurochemical and endocrinological abnormalities.

1981 • 11 citations

Anin vitro model of alcohol and acetaldehyde teratogenicity

1982 • 10 citations

Derangement in cardiac protein metabolism in fetal alcohol syndrome.

1979 • 9 citations

Growth of Rat Embryos in the Serum of Alcohol Drinkers

1984 • 9 citations

Prenatal loss in the rat following moderate consumption of alcohol incorporated in a liquid diet.

1983 • 8 citations

Fetal alcohol syndrome in the ferret (Mustela putorius)

1984 • 8 citations

The Fetal Alcohol Syndrome

1982 • 7 citations

Comparison of the offspring of three serial pregnancies during voluntary alcohol consumption in Sinclair (S-1) miniature swine.

1983 • 7 citations

The effect of ethanol upon early development in mice and rats. II. In vitro effect upon early postimplantation rat embryos.

1980 • 7 citations

Teratogenesis and the Movement of Ions

1975 • 5 citations

The effect of ethanol upon early development in mice and rats. VI. In vivo effect of acetaldehyde upon preimplantation stages in rats.

1984 • 4 citations

Publisher's note (i)

1982 • 3 citations

The effect of chronic oral alcoholization upon late fetal development in mice.

1982 • 1 citations

Deleted Work

1955 • 0 citations