The mouse lethal nonagouti (a(x)) mutation deletes the S-adenosylhomocysteine hydrolase (Ahcy) gene.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.

1991 • 1,358 citations

Cloning of the T gene required in mesoderm formation in the mouse

1990 • 847 citations

Molecular characterization of the mouse agouti locus

1992 • 791 citations

The Enzymatic Synthesis of S-Adenosyl-l-homocysteine from Adenosine and Homocysteine

1959 • 546 citations

X-RAY-INDUCED MUTATIONS IN MICE

1951 • 486 citations

Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation.

1993 • 428 citations

Embryonic lethal mutation in mice induced by retrovirus insertion into the α1(I) collagen gene

1983 • 422 citations

Apparent suicide inactivation of human lymphoblast S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine and adenine arabinoside. A basis for direct toxic effects of analogs of adenosine.

1979 • 277 citations

Pyrimidine Starvation Induced by Adenosine in Fibroblasts and Lymphoid Cells: Role of Adenosine Deaminase

1973 • 271 citations

Role of S-adenosylhomocysteine in adenosine-mediated toxicity in cultured mouse T lymphoma cells

1977 • 267 citations

The embryonic lethality of homozygous lethal yellow mice (Ay/Ay) is associated with the disruption of a novel RNA-binding protein.

1993 • 171 citations

S-Adenosylhomocysteine Metabolism in Various Species

1975 • 144 citations

Altered rhombomere-specific gene expression and hyoid bone differentiation in the mouse segmentation mutant, kreisler (kr)

1993 • 144 citations

S -Adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin

1979 • 124 citations

Adenine and Adenosine Are Toxic to Human Lymphoblast Mutants Defective in Purine Salvage Enzymes

1977 • 112 citations

Methylation, expression and chromosomal position of genes in mammals

1984 • 100 citations

Recombinant inbred strain and interspecific backcross analysis of molecular markers flanking the murine agouti coat color locus.

1989 • 97 citations

MOLECULAR GENETIC ANALYSIS OF THE DILUTE-SHORT EAR (d-se) REGION OF THE MOUSE

1986 • 89 citations

Identification and characterization of a novel, evolutionarily conserved gene disrupted by the murine Hβ58 embryonic lethal transgene insertion

1992 • 88 citations

Prenatal determination of obesity, tumor susceptibility, and coat color pattern in viable yellow (Avy/a) mice

1986 • 79 citations

The relationship between embryonic, embryonal carcinoma and embryo-derived stem cells

1984 • 66 citations

Gastrulation in the mouse: assessment of cell populations in the epiblast of tw18/tw18 embryos.

1978 • 62 citations

Sequence of full length cDNA for human S‐adenosylhomocysteine hydrolase.

1989 • 61 citations

Insertional Mutations in Transgenic Mice

1989 • 60 citations

Mouse chromosome 2

1997 • 60 citations

Amino acid sequence of S-adenosyl-L-homocysteine hydrolase from rat liver as derived from the cDNA sequence.

1987 • 57 citations

Cloning of the gene encoding Leishmania donovaniS-adenosylhomocysteine hydrolase, a potential target for antiparasitic chemotherapy

1992 • 56 citations

S-Adenosylhomocysteine hydrolase from human placenta. Affinity purification and characterization

1985 • 53 citations

The albino–deletion complex in the mouse defines genes necessary for development of embryonic and extraembryonic ectoderm*

1989 • 50 citations

Regional localization of the human genes for S-adenosylhomocysteine hydrolase (cen?q131) and adenosine deaminase (q131?qter) on chromosome 20

1984 • 48 citations

The Human Genes for S -Adenosylhomocysteine Hydrolase and Adenosine Deaminase Are Syntenic on Chromosome 20

1982 • 45 citations

Development of lethal yellow (A^y/A^y) mouse embryos in vitro

1974 • 42 citations

Molecular analysis of viable spontaneous and radiation-induced albino (c)-locus mutations in the mouse

1993 • 41 citations

Genetic Organization of the agouti Region of the Mouse

1987 • 40 citations

Molecular Markers for the agouti Coat Color Locus of the Mouse

1987 • 39 citations

Influence of S-adenosylhomocysteine hydrolase inhibitors on S-adenosylhomocysteine and S-adenosylmethionine pool levels in L929 cells

1990 • 35 citations

Paradoxical expression of adenosine deaminase in T cells cultured from a patient with adenosine deaminase deficiency and combine immunodeficiency.

1990 • 35 citations

Death of mouse embryos that lack a functional gene for glucose phosphate isomerase

1990 • 34 citations

Activation of collagen IV gene expression in F9 teratocarcinoma cells by 3-deazaadenosine analogs. Indirect inhibitors of methylation.

1992 • 34 citations

Amino acid sequence of S-adenosyl-L-homocysteine hydrolase from Dictyosteliumdiscoideum as deduced from the cDNA sequence

1988 • 28 citations

Basis for Resistance to 3-Deazaaristeromycin, an Inhibitor of S-Adenosylhomocysteine Hydrolase, in Human B-Lymphoblasts

1989 • 26 citations

Perturbations in S-adenosyl-homocysteine and S-adenosyl-methionine metabolism: Effects on transmethylation

1980 • 25 citations

The long-range restriction map surrounding the mouse agouti locus reveals a disparity between physical and genetic distances

1989 • 22 citations

Physical and genetic characterization of a 75-kilobase deletion associated with al, a recessive lethal allele at the mouse agouti locus.

1989 • 22 citations

Mouse Chromosome 2

1992 • 22 citations

A recessive allele of the mouse agouti locus showing lethality with yellow,A^y

1985 • 19 citations

PSEUDOALLELISM AT THE AGOUTI LOCUS IN THE MOUSE

1965 • 14 citations

Molecular characterization in the dpy-14 region identifies the S-adenosylhomocysteine hydrolase gene in Caenorhabditis elegans

1993 • 13 citations

Expression of TAPA-1 in preimplantation mouse embryos

1992 • 12 citations

Effect of methylation inhibitors on gene expression in HL-60 cells

1992 • 9 citations

Genomic Organization and Molecular Genetics of the Agouti Locus in the Mouse^a

1991 • 9 citations

Association of Xmv-10 and the non-agouti (a) mutation explained by close linkage instead of causality

1994 • 8 citations

Mapping of the structural gene for S-adenosyl homocysteine hydrolase to mouse Chromosome 2, and related sequences to Chromosomes 8 and X

1992 • 8 citations