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A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

1993 • 1,893 citations

Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

1992 • 1,792 citations

COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum

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Reconstitution of the transport of protein between successive compartments of the golgi measured by the coupled incorporation of N-acetylglucosamine

1984 • 689 citations

The syntaxin family of vesicular transport receptors

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Vesicle fusion from yeast to man

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A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast

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1988 • 519 citations

Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein

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A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles

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1992 • 472 citations

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Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transport.

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1994 • 395 citations

Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack

1988 • 389 citations

Sec9 is a SNAP-25-like component of a yeast SNARE complex that may be the effector of Sec4 function in exocytosis

1994 • 380 citations

Membrane fusion machinery: Insights from synaptic proteins

1993 • 380 citations

Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.

1991 • 347 citations

The role of clathrin, adaptors and dynamin in endocytosis

1994 • 343 citations

The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling.

1995 • 338 citations

Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles.

1991 • 318 citations

Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae

1993 • 316 citations

SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex.

1992 • 311 citations

Stepwise assembly of functionally active transport vesicles

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Vesicular transport between the endoplasmic reticulum and the Golgi stack requires the NEM-sensitive fusion protein

1989 • 288 citations

A multisubunit particle implicated in membrane fusion.

1992 • 271 citations

rbSec1A and B colocalize with syntaxin 1 and SNAP-25 throughout the axon, but are not in a stable complex with syntaxin.

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Disassembly of the reconstituted synaptic vesicle membrane fusion complex in vitro.

1995 • 262 citations

Vesicle fusion following receptor-mediated endocytosis requires a protein active in Golgi transport

1989 • 250 citations

Different requirements for NSF, SNAP, and Rab proteins in apical and basolateral transport in MDCK cells

1995 • 241 citations

Vesicle-associated membrane protein and synaptophysin are associated on the synaptic vesicle.

1994 • 240 citations

Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product.

1988 • 220 citations

Ca2+ and secretory-vesicle dynamics

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Domain structure of an N-ethylmaleimide-sensitive fusion protein involved in vesicular transport.

1993 • 178 citations

BET1, BOS1, and SEC22 Are Members of a Group of Interacting Yeast Genes Required for Transport from the Endoplasmic Reticulum to the Golgi Complex

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Localization of Sed5, a putative vesicle targeting molecule, to the cis-Golgi network involves both its transmembrane and cytoplasmic domains.

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Purification of three related peripheral membrane proteins needed for vesicular transport.

1990 • 147 citations

Characteristics of endoplasmic reticulum-derived transport vesicles.

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Synaptic vesicle exocytosis: Molecules and models

1994 • 107 citations

The karyogamy gene KAR2 and novel proteins are required for ER-membrane fusion

1994 • 104 citations

The ATPase activity of N-ethylmaleimide-sensitive fusion protein (NSF) is regulated by soluble NSF attachment proteins.

1994 • 104 citations

The BOS1 gene encodes an essential 27-kD putative membrane protein that is required for vesicular transport from the ER to the Golgi complex in yeast.

1991 • 97 citations

Identification and Structure of Four Yeast Genes (SLY) That Are Able To Suppress the Functional Loss of YPT1, a Member of the RAS Superfamily

1991 • 97 citations

Soluble N-ethylmaleimide-sensitive fusion attachment proteins (SNAPs) bind to a multi-SNAP receptor complex in Golgi membranes.

1992 • 93 citations

Syntaxin 1 (HPC-1) Is Associated with Chromaffin Granules

1995 • 91 citations

Multiple N-ethylmaleimide-sensitive components are required for endosomal vesicle fusion.

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Characterization of a Component of the Yeast Secretion Machinery: Identification of the SEC18 Gene Product

1988 • 79 citations

Control of protein traffic between distinct plasma membrane domains. Requirement for a novel 108,000 protein in the fusion of transcytotic vesicles with the apical plasma membrane.

1993 • 71 citations

Expression of vesicle-associated membrane protein 2 (VAMP-2)/synaptobrevin II and cellubrevin in rat skeletal muscle and in a muscle cell line

1994 • 68 citations

Expression of the synaptic vesicle proteins VAMPs/synaptobrevins 1 and 2 in non-neural tissues.

1994 • 61 citations

Association of N‐ethylmaleimide‐sensitive factor with synaptic vesicles

1994 • 58 citations

Yeast and mammals utilize similar cytosolic components to drive protein transport through the Golgi complex.

1986 • 52 citations

Role of two nucleotide-binding regions in an N-ethylmaleimide-sensitive factor involved in vesicle-mediated protein transport.

1994 • 50 citations

The activity of Golgi transport vesicles depends on the presence of the N-ethylmaleimide-sensitive factor (NSF) and a soluble NSF attachment protein (alpha SNAP) during vesicle formation.

1992 • 45 citations

Isolation of functional, coated, endocytic vesicles.

1991 • 42 citations

[29] Expression and purification of recombinant N-ethylmaleimide-sensitive fusion protein from Escherichia coli

1992 • 15 citations

Selective action of uncoating atpase towards clathrin-coated vesicles from brain

1995 • 14 citations