Human Placenta Thioredoxin Reductase: Preparation and Inhibitor Studies

Physiological functions of thioredoxin and thioredoxin reductase

2000 • 2,440 citations

[8] Reassessment of Ellman's reagent

1983 • 1,076 citations

Human Placenta Thioredoxin Reductase

1998 • 519 citations

Substitution of the Thioredoxin System for Glutathione Reductase in Drosophila melanogaster

2001 • 394 citations

Thioredoxin reductase as a pathophysiological factor and drug target

2000 • 382 citations

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2000 • 335 citations

Preparation and assay of mammalian thioredoxin and thioredoxin reductase

1999 • 316 citations

Bovine thioredoxin system. Purification of thioredoxin reductase from calf liver and thymus and studies of its function in disulfide reduction.

1977 • 294 citations

Rat and Calf Thioredoxin Reductase Are Homologous to Glutathione Reductase with a Carboxyl-terminal Elongation Containing a Conserved Catalytically Active Penultimate Selenocysteine Residue

1998 • 261 citations

The Thioredoxin System of the Malaria Parasite Plasmodium falciparum

2000 • 246 citations

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2000 • 237 citations

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1999 • 236 citations

Mammalian Thioredoxin Reductase Is Irreversibly Inhibited by Dinitrohalobenzenes by Alkylation of Both the Redox Active Selenocysteine and Its Neighboring Cysteine Residue

1998 • 199 citations

1-Chloro-2,4-dinitrobenzene Is an Irreversible Inhibitor of Human Thioredoxin Reductase

1995 • 185 citations

Human Thioredoxin Reductase Is Efficiently Inhibited by (2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes. Possible Implications for a Novel Antitumor Strategy

2001 • 142 citations

The mechanism of action of the nitrosourea anti-tumor drugs on thioredoxin reductase, glutathione reductase and ribonucleotide reductase

1990 • 119 citations

Determination of Thioredoxin Reductase Activity in Rat Liver Supernatant

1997 • 110 citations

Interaction of a glutathione S‐conjugate with glutathione reductase Kinetic and X‐ray crystallographic studies

1984 • 86 citations

Azelaic acid as a competitive inhibitor of thioredoxin reductase in human melanoma cells

1987 • 77 citations

Mechanism-based inhibition of thioredoxin reductase by antitumor quinoid compounds

1992 • 64 citations

The 58 kDa mouse selenoprotein is a BCNU‐sensitive thioredoxin reductase

1997 • 62 citations

Glutathione reductase: solvent equilibrium and kinetic isotope effects

1988 • 51 citations

The role of the C‐terminus for catalysis of the large thioredoxin reductase from Plasmodium falciparum

1998 • 45 citations

Application of a Single-Plasmid Vector for Mutagenesis and High-Level Expression of Thioredoxin Reductase and Its Use to Examine Flavin Cofactor Incorporation

1997 • 43 citations

Overexpression of wild type and SeCys/Cys mutant of human thioredoxin reductase in E. coli: the role of selenocysteine in the catalytic activity

2001 • 42 citations

Superoxide production by dinitrophenyl‐ derivatized thioredoxin reductase ‐ a model for the mechanism and correlation to immunostimulation by dinitrohalobenzenes

1999 • 29 citations

Reversible inhibition of human thioredoxin reductase activity by cytotoxic alkyl 2-imidazolyl disulfide analogues

1994 • 26 citations

News and views on thioredoxin reductases

1999 • 24 citations

Inhibition Of Thioredoxin Reductase (E.C. 1.6.4.5.) By Antitumor Quinones

1990 • 20 citations

Microinjected glutathione reductase crystals as indicators of the redox status in living cells

1999 • 19 citations

Purification of Red Cell Enzymes by Treatment with n-Butanol and Chloroform

1976 • 12 citations

Purification, crystallization and preliminary crystallographic data for rat cytosolic selenocysteine 498 to cysteine mutant thioredoxin reductase

2000 • 9 citations