Probing the phosphocholine-binding site of human C-reactive protein by site-directed mutagenesis.

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

1962 • 6,970 citations

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.

1987 • 2,266 citations

THE PHENOMENON OF THE ACUTE PHASE RESPONSE*

1982 • 1,498 citations

SEROLOGICAL REACTIONS IN PNEUMONIA WITH A NON-PROTEIN SOMATIC FRACTION OF PNEUMOCOCCUS

1930 • 1,460 citations

Acute Phase Proteins with Special Reference to C-Reactive Protein and Related Proteins (Pentaxins) and Serum Amyloid A Protein

1983 • 1,283 citations

Human GM-CSF: Molecular Cloning of the Complementary DNA and Purification of the Natural and Recombinant Proteins

1985 • 1,253 citations

[32] Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

1983 • 1,093 citations

Specificity of C-Reactive Protein for Choline Phosphate Residues of Pneumococcal C-Polysaccharide

1971 • 396 citations

Characterization of C-reactive protein and the complement subcomponent C1t as homologous proteins displaying cyclic pentameric symmetry (pentraxins).

1977 • 380 citations

Nucleotide sequence of a full-length complementary DNA clone and amino acid sequence of human phenylalanine hydroxylase

1985 • 325 citations

Interaction of C-reactive protein with artificial phosphatidylcholine bilayers

1979 • 235 citations

Binding of C-reactive protein to chromatin and nucleosome core particles. A possible physiological role of C-reactive protein.

1984 • 183 citations

Expression, detection and assay of a neoantigen (Neo-CRP) associated with a free, human C-reactive protein subunit

1987 • 151 citations

The Chemical Composition of Pneumococcal C-Polysaccharide

1963 • 130 citations

Genomic DNA sequence for human C-reactive protein.

1985 • 129 citations

Structural basis for the specificity of phosphorylcholine-binding immunoglobulins

1976 • 125 citations

C-reactive protein reacts with the U1 small nuclear ribonucleoprotein.

1989 • 125 citations

Interactions of C-reactive protein with the complement system. II. C-reactive protein-mediated consumption of complement by poly-L-lysine polymers and other polycations.

1975 • 125 citations

C-reactive protein: purification by affinity chromatography and physicochemical characterization

1978 • 124 citations

C-reactive protein: a molecule composed of subunits.

1965 • 119 citations

Binding of fibronectin by the acute phase reactant C-reactive protein.

1984 • 115 citations

Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in mice.

1982 • 112 citations

Analysis of the binding of C-reactive protein to histones and chromatin.

1988 • 101 citations

Human serum amyloid P component. cDNA isolation, complete sequence of pre-serum amyloid P component, and localization of the gene to chromosome 1.

1985 • 100 citations

Comparative studies on the binding properties of human and rabbit C-reactive proteins.

1980 • 100 citations

Molecular genetics, structure, and function of C-reactive protein

1991 • 87 citations

Binding reactivity of C-reactive protein for polycations.

1980 • 81 citations

Isolation of C-reactive protein by affinity chromatography.

1977 • 79 citations

Isolation and characterization of Limulus C-reactive protein genes.

1986 • 79 citations

C-reactive protein and serum amyloid P component in the plaice (Pleuronectes platessa L.), a marine teleost, are homologous with their human counterparts

1982 • 70 citations

Comparison of the Secondary Structures and Binding Sites of C-Reactive Protein and the Phosphorylcholine-Binding Murine Myeloma Proteins

1978 • 58 citations

Demonstration of calcium-induced conformational change(s) in C-reactive protein by using monoclonal antibodies

1982 • 58 citations

Localization of the phosphocholine-binding sites on C-reactive protein by immunoelectron microscopy.

1983 • 50 citations

Somatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region.

1987 • 48 citations

Attempts to locate residues in complementarity-determining regions of antibody combining sites that make contact with antigen.

1976 • 42 citations

Degradation of a Pneumococcal Type-Specific Polysaccharide with Exposure of Group-Specificity

1970 • 41 citations

Isolation of C-reactive proteins of man monkey, rabbit and dog by affinity chromatography on phosphorylated cellulose

1970 • 41 citations

Syrian Hamster Female Protein: Analysis of Female Protein Primary Structure and Gene Expression

1985 • 38 citations

Derivation of the amino acid sequence of rat C-reactive protein from cDNA cloning with additional studies on the nature of its dimeric component.

1992 • 35 citations

Structure of the mouse C-reactive protein gene

1988 • 24 citations

Rabbit C-reactive protein. Biosynthesis and characterization of cDNA clones.

1986 • 23 citations

C-reactive protein (CRP) of the syrian hamster

1991 • 21 citations

Rat serum amyloid P component. Analysis of cDNA sequence and gene expression

1990 • 20 citations

[36] C-reactive protein

1988 • 20 citations

Binding and immunological properties of a synthetic peptide corresponding to the phosphorylcholine-binding region of C-reactive protein

1990 • 19 citations

Structure of the mouse serum amyloid P component gene

1988 • 15 citations

Synthesis and use of new spin labeled derivatives of phosphorylcholine in a comparative study of human, dogfish, and Limulus C-reactive proteins.

1983 • 14 citations

LOCALIZATION OF C-REACTIVE PROTEIN IN SYNOVIUM OF PATIENTS WITH RHEUMATOID ARTHRITIS

1977 • 14 citations

Purification of human C-reactive protein by immunoaffinity chromatography using mouse monoclonal antibody

1990 • 6 citations

COMPARATIVE STUDIES ON THE BINDING SPECIFICITIES OF C‐REACTIVE PROTEIN (CRP) AND HOPC 8*

1982 • 5 citations