Modulation of human neutrophilic granulocyte functions by recombinant human tumor necrosis factor and recombinant human lymphotoxin. Promotion of adherence, inhibition of chemotactic migration and superoxide anion release from adherent cells.

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

THE CHEMOTACTIC EFFECT OF MIXTURES OF ANTIBODY AND ANTIGEN ON POLYMORPHONUCLEAR LEUCOCYTES

1962 • 2,726 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

LEUKOCYTE LOCOMOTION AND CHEMOTAXIS

1973 • 1,709 citations

Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.

1985 • 1,056 citations

Human tumor necrosis factor. Production, purification, and characterization.

1985 • 922 citations

Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factors.

1985 • 922 citations

Characterization of receptors for human tumour necrosis factor and their regulation by γ-interferon

1985 • 896 citations

Stimulation of neutrophils by tumor necrosis factor.

1986 • 847 citations

Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes.

1987 • 823 citations

Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival.

1986 • 733 citations

Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity

1984 • 638 citations

Molecular Cloning of the Complementary DNA for Human Tumor Necrosis Factor

1985 • 633 citations

Neutrophil chemotactic factor produced by lipopolysaccharide (LPS)-stimulated human blood mononuclear leukocytes: partial characterization and separation from interleukin 1 (IL 1).

1987 • 613 citations

An endothelial cell surface factor(s) induced in vitro by lipopolysaccharide, interleukin 1, and tumor necrosis factor-alpha increases neutrophil adherence by a CDw18-dependent mechanism.

1986 • 593 citations

Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator

1985 • 566 citations

Tumor necrosis factor is chemotactic for monocytes and polymorphonuclear leukocytes.

1987 • 533 citations

Purified Human Granulocyte-Macrophage Colony-Stimulating Factor: Direct Action on Neutrophils

1984 • 506 citations

Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor

1985 • 464 citations

Macrophages as a source of tumoricidal activity (tumor-necrotizing factor)

1980 • 398 citations

Tumor necrosis factor provokes superoxide anion generation from neutrophils

1986 • 307 citations

Human recombinant granulocyte-macrophage colony-stimulating factor increases cell-to-cell adhesion and surface expression of adhesion-promoting surface glycoproteins on mature granulocytes.

1986 • 284 citations

Immune interferon enhances functional properties of human granulocytes: role of Fc receptors and effect of lymphotoxin, tumor necrosis factor, and granulocyte-macrophage colony-stimulating factor.

1987 • 254 citations

Biosynthetic human GM-CSF modulates the number and affinity of neutrophil f-Met-Leu-Phe receptors.

1986 • 218 citations

Chemotactic cytokines: the role of leukocytic pyrogen and epidermal cell thymocyte-activating factor in neutrophil chemotaxis.

1984 • 215 citations

Human recombinant interleukin 1 beta has no effect on intracellular calcium or on functional responses of human neutrophils.

1987 • 131 citations

Mononuclear cell-mediated enhancement of granulocyte function in man.

1984 • 57 citations

The Effect of Bovine Serum Albumin and the Chemotactic Peptide Formyl-Methionyl-Leucyl-Phenylalanin on the Adherence of Guinea Pig Polymorphonuclear Leukocytes to Nylon Fiber Columns

1981 • 12 citations

Differential effects of nylon fibre adherence on the production of superoxide anion by human polymorphonuclear neutrophilic granulocytes stimulated with chemoattractants, ionophore A23187 and phorbol myristate acetate.

1987 • 11 citations

Bronchial asthma, leukocyte synthesis of slow-reacting substance of anaphylaxis, and other evidence for activation of blood cells in asthma

1986 • 5 citations