Substance P-induced augmentation of cutaneous vascular permeability and granulocyte infiltration in mice is mast cell dependent.

Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation

1979 • 1,199 citations

DIRECT EVIDENCE FOR NEUROGENIC INFLAMMATION AND ITS PREVENTION BY DENERVATION AND BY PRETREATMENT WITH CAPSAICIN

1967 • 1,100 citations

Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation

1978 • 846 citations

Decrease of mast cells in W/Wv mice and their increase by bone marrow transplantation

1978 • 634 citations

Intestinal mucosal mast cells in normal and nematode-infected rat intestines are in intimate contact with peptidergic nerves.

1987 • 554 citations

Neutral endopeptidase 24.11 (enkephalinase) and related regulators of peptide hormones ¹

1989 • 552 citations

Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.

1985 • 503 citations

Flare and Itch Induced by Substance P in Human Skin

1978 • 460 citations

Mast cell heterogeneity: effects of neuroenteric peptides on histamine release.

1985 • 440 citations

Release of Histamine from Mast Cells by Vasoactive Peptides

1973 • 389 citations

Decreased production of mast cells in S1/S1d anemic mice

1979 • 372 citations

The effects of substance P on histamine and 5‐hydroxytryptamine release in the rat

1982 • 347 citations

Structure‐activity relationships for some substance P‐related peptides that cause wheal and flare reactions in human skin.

1983 • 319 citations

Purification and characterization of human skin mast cells. Evidence for human mast cell heterogeneity.

1987 • 257 citations

Suggestive evidence for a direct innervation of mucosal mast cells

1983 • 239 citations

125I-fibrin deposition in IgE-dependent immediate hypersensitivity reactions in mouse skin. Demonstration of the role of mast cells using genetically mast cell-deficient mice locally reconstituted with cultured mast cells.

1987 • 214 citations

Genetically mast-cell-deficient W/Wv and Sl/Sld mice. Their value for the analysis of the roles of mast cells in biologic responses in vivo.

1987 • 206 citations

Substance P induces granulocyte infiltration through degranulation of mast cells.

1989 • 195 citations

Histamine release and vascular changes induced by neuropeptides

1983 • 182 citations

Substance P and Calcitonin Gene-Related Peptide: Effects on Mast Cells and in Human Skin

1987 • 162 citations

Neuropeptide regulation of the expression of immediate hypersensitivity

1985 • 159 citations

Electron microscopical evidence for a direct contact between nerve fibres and mast cells

1981 • 156 citations

Suggestive evidence for a functional unit between mast cells and substance P fibers in the rat diaphragm and mesentery

1985 • 154 citations

Rejection of first-set skin allografts in man. the microvasculature is the critical target of the immune response.

1979 • 134 citations

Neurogenic inflammation, vascular permeability, and mast cells.

1988 • 132 citations

Mast cell-dependent amplification of an immunologically nonspecific inflammatory response. Mast cells are required for the full expression of cutaneous acute inflammation induced by phorbol 12-myristate 13-acetate.

1988 • 127 citations

Studies on pruritogenic and histamine-releasing effects of some putative peptide neurotransmitters

1981 • 122 citations

Unequivocal Delayed Hypersensitivity in Mast Cell-Deficient and Beige Mice

1984 • 121 citations

Substance P-Induced Histamine Release in Human Cutaneous Mast Cells

1987 • 120 citations

Studies on the trigeminal antidromic vasodilatation and plasma extravasation in the rat.

1984 • 116 citations

Neutral endopeptidase-like enzyme controls the contractile activity of substance P in guinea pig lung.

1987 • 105 citations

The role of the N-terminal tetrapeptide in the histamine releasing action of substance P

1981 • 99 citations

THE INVOLVEMENT OF MAST CELLS IN VASODILATATION DUE TO AXON REFLEXES IN INJURED SKIN

1972 • 99 citations

Role of mast cells in anaphylaxis. Evidence for the importance of mast cells in the cardiopulmonary alterations and death induced by anti-IgE in mice.

1989 • 98 citations

Phenotypic changes of bone marrow-derived mast cells after intraperitoneal transfer into W/Wv mice that are genetically deficient in mast cells.

1987 • 97 citations

Quantitation of fibrinogen influx and fibrin deposition and turnover in line 1 and line 10 guinea pig carcinomas.

1984 • 80 citations

Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitro and in vivo passage of clonal mast cell populations derived from mouse peritoneal mast cells

1988 • 71 citations

Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitro and in vivo passage of clonal mast cell populations derived from mouse peritoneal mast cells

1988 • 64 citations

Antidromic vasodilatation in the rat hindpaw measured by laser Doppler flowmetry: pharmacological modulation

1987 • 48 citations

Undiminished immunologic tolerance to contact sensitivity in mast cell-deficient W/Wv and Sl/Sld mice.

1985 • 46 citations

Vasodilating Action of Substance P in the Human Forearm

1965 • 42 citations

A STUDY OF CHEMICALLY INDUCED ACUTE INFLAMMATION IN THE SKIN OF THE RAT

1977 • 34 citations

Functional Heterogeneity of Human Mast Cells

1991 • 31 citations

A substance P antagonist inhibits heat‐induced oedema in the rat skin

1984 • 27 citations

125I-fibrin deposition in contact sensitivity reactions in the mouse. Sensitivity of the assay for quantitating reactions after active or passive sensitization.

1986 • 17 citations

The Innervation of Mast Cells

2018 • 5 citations

Deleted Work

1955 • 0 citations