Multiple mechanisms regulate c-myc gene expression during normal T cell activation.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1981 • 1,611 citations

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

Transcriptional regulation of hemoglobin switching in chicken embryos.

1981 • 800 citations

Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester

1985 • 753 citations

THE myc ONCOGENE: ITS ROLE IN TRANSFORMATION AND DIFFERENTIATION

1986 • 714 citations

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

1987 • 696 citations

Evolution of tumours and the impact of molecular oncology

1985 • 666 citations

Extreme instability of myc mRNA in normal and transformed human cells.

1984 • 522 citations

T-Cell Proliferation Involving the CD28 Pathway Is Associated witH Cyclosporine-Resistant Interleukin 2 Gene Expression

1987 • 522 citations

Cloning and sequencing of a deoxyribonucleic acid copy of glyceraldehyde 3-phosphate dehydrogenase messenger ribonucleic acid isolated from chicken muscle

1983 • 486 citations

Enhanced Transcription of c- myc in Bursal Lymphoma Cells Requires Continuous Protein Synthesis

1985 • 469 citations

Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours.

1983 • 436 citations

Levels of c-myc oncogene mRNA are invariant throughout the cell cycle

1985 • 426 citations

Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters

1987 • 379 citations

Isolation and partial nucleotide sequence of a cDNA clone for human histocompatibility antigen HLA-B by use of an oligodeoxynucleotide primer.

1981 • 374 citations

c-myc oncogene protein synthesis is independent of the cell cycle in human and avian cells

1985 • 371 citations

Expression of the c-myb proto-oncogene during cellular proliferation

1986 • 360 citations

c-myc gene expression is stimulated by agents that activate protein kinase C and does not account for the mitogenic effect of PDGF

1985 • 331 citations

Intragenic pausing and anti-sense transcription within the murine c-myc locus.

1986 • 326 citations

c-myc gene is transcribed at high rate in G0-arrested fibroblasts and is post-transcriptionally regulated in response to growth factors

1985 • 300 citations

Cell Surface Molecules and Early Events Involved in Human T Lymphocyte Activation

1987 • 297 citations

Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus

1984 • 274 citations

Enforced expression of the c-myc oncogene inhibits cell differentiation by precluding entry into a distinct predifferentiation state in G0/G1.

1988 • 273 citations

Metabolism of c-myc gene products: c-myc mRNA and protein expression in the cell cycle.

1985 • 271 citations

Transcriptional Regulation of Hemoglobin Switching in Chicken Embryos

1981 • 265 citations

Transcriptional arrest within the first exon is a fast control mechanism in c-myc gene expression

1986 • 254 citations

Sequence requirements for premature termination of transcription in the human c-myc gene

1988 • 246 citations

Mutations in the First Exon Are Associated with Altered Transcription of c- myc in Burkitt Lymphoma

1987 • 228 citations

Novel promoter upstream of the human c-myc gene and regulation of c-myc expression in B-cell lymphomas.

1986 • 176 citations

Aberrant c-myc RNAs of Burkitt's lymphoma cells have longer half-lives.

1985 • 152 citations

c-myc regulation during retinoic acid-induced differentiation of F9 cells is posttranscriptional and associated with growth arrest.

1986 • 147 citations

Multiple mechanisms regulate c-myc gene expression during normal T cell activation.

1988 • 124 citations

Specific inhibition of c-myc protein biosynthesis using an antisense synthetic deoxy-oligonucleotide in human T lymphocytes.

1988 • 119 citations

Calcium ionophore A23187 as a regulator of gene expression in mammalian cells.

1986 • 109 citations

The specific induction of myc protooncogene expression in normal human B cells is not a sufficient event for acquisition of competence to proliferate.

1985 • 97 citations

Recombinant interleukin 2 regulates levels of c-myc mRNA in a cloned murine T lymphocyte.

1985 • 80 citations

Regulation of expression of the c‐Myc proto‐oncogene

1987 • 78 citations

Stimulation of T Cells Through the CD3/T-Cell Receptor Complex: Role of Cytoplasmic Calcium, Protein Kinase C Translocation, and Phosphorylation of pp60^c-src in the Activation Pathway

1987 • 66 citations

A calcium ionophore-inducible cellular promoter is highly active and has enhancerlike properties.

1986 • 51 citations

Novel Promoter Upstream of the Human c-myc Gene and Regulation of c-myc Expression in B-Cell Lymphomas

1986 • 50 citations

Enforced Expression of the c-myc Oncogene Inhibits Cell Differentiation by Precluding Entry into a Distinct Predifferentiation State in G₀/G₁

1988 • 49 citations

Complex translocation disrupts c-myc regulation in a human plasma cell myeloma.

1988 • 47 citations

Expression of c-myc RNA in bursal lymphoma cell lines: Identification of c-myc-encoded proteins by hybrid-selected translation

1983 • 44 citations

c-myc Regulation during Retinoic Acid-Induced Differentiation of F9 Cells Is Posttranscriptional and Associated with Growth Arrest

1986 • 24 citations

A Calcium Ionophore-Inducible Cellular Promoter is Highly Active and has Enhancerlike Properties

1986 • 24 citations

Two-step stimulation of B lymphocytes to enter DNA synthesis: synergy between anti-immunoglobulin antibody and cytochalasin on expression of c-myc and a G1-specific gene.

1988 • 23 citations

Recombinant Interleukin 2 Regulates Levels of c-myc mRNA in a Cloned Murine T Lymphocyte

1985 • 21 citations

Regulation of c-myc transcription and protein expression during activation of normal human B cells

1987 • 18 citations

Downregulation of c-myc RNA is not a prerequisite for reduced cell proliferation, but is associated with G1 arrest in B-lymphoid cell lines

1987 • 16 citations

Two-Step Stimulation of B Lymphocytes to Enter DNA Synthesis: Synergy Between Anti-Immunoglobulin Antibody and Cytochalasin on Expression of c-myc and a G₁-Specific Gene

1988 • 4 citations