Neuronal NOS-cGMP-dependent ACh-induced relaxation in pial arterioles of endothelial NOS knockout mice

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

1981 • 1,624 citations

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

1994 • 1,578 citations

Targeted disruption of the neuronal nitric oxide synthase gene

1993 • 1,300 citations

Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one.

1995 • 1,102 citations

Nitric oxide and the cerebral circulation.

1994 • 540 citations

cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase.

1996 • 473 citations

Reduced Brain Edema and Infarction Volume in Mice Lacking the Neuronal Isoform of Nitric Oxide Synthase after Transient MCA Occlusion

1996 • 422 citations

Possible Origins and Distribution of Immunoreactive Nitric Oxide Synthase-Containing Nerve Fibers in Cerebral Arteries

1993 • 382 citations

Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase.

1996 • 349 citations

The NOS Inhibitor, 7-Nitroindazole, Decreases Focal Infarct Volume but Not the Response to Topical Acetylcholine in Pial Vessels

1994 • 298 citations

Strain-Related Differences in Susceptibility to Transient Forebrain Ischemia in SV-129 and C57Black/6 Mice

1997 • 249 citations

Possible role of nitric oxide in transmitting information from vasodilator nerve to cerebroarterial muscle

1990 • 180 citations

The Role of Neuronal Nitric Oxide Synthase in Regulation of Cerebral Blood Flow in Normocapnia and Hypercapnia in Rats

1995 • 171 citations

Regional cerebral blood flow response to vibrissal stimulation in mice lacking type I NOS gene expression

1996 • 139 citations

ACh dilates pial arterioles in endothelial and neuronal NOS knockout mice by NO-dependent mechanisms

1996 • 112 citations

Importance of Nitric Oxide Synthase Inhibition to the Attenuated Vascular Responses Induced by Topical L-Nitroarginine during Vibrissal Stimulation

1994 • 110 citations

Effects of a Novel Inhibitor of Guanylyl Cyclase on Dilator Responses of Mouse Cerebral Arterioles

1997 • 107 citations

Cerebrovascular Responses under Controlled and Monitored Physiological Conditions in the Anesthetized Mouse

1995 • 100 citations

L-NA-Sensitive rCBF Augmentation during Vibrissal Stimulation in Type III Nitric Oxide Synthase Mutant Mice

1996 • 99 citations

Novel guanylyl cyclase inhibitor potently inhibits cyclic GMP accumulation in endothelial cells and relaxation of bovine pulmonary artery.

1996 • 98 citations

7-Nitroindazole Inhibits Brain Nitric Oxide Synthase and Cerebral Vasodilatation in Response to N -Methyl- <scp>d</scp> -aspartate

1995 • 92 citations

Hypoglycaemic and insulinotropic effects of a novel oral antidiabetic agent, (−)‐N‐(trans‐4‐isopropylcyclohexane‐carbonyl)‐<scp>d</scp>‐phenylalanine (A‐4166)

1997 • 91 citations

Nitric Oxide Mediates the Neurogenic Vasodilation of Bovine Cerebral Arteries

1991 • 88 citations

In vivo microdialysis study of a specific inhibitor of soluble guanylyl cyclase on the glutamate receptor/nitric oxide/cyclic GMP pathway

1996 • 73 citations

Endothelium-derived Vasoactive Factors and Regulation of the Cerebral Circulation

1993 • 69 citations

Inhibition of nitrergic relaxations by a selective inhibitor of the soluble guanylate cyclase

1996 • 64 citations

Brain distribution of nitric oxide synthase in neuronal or endothelial nitric oxide synthase mutant mice using [3H]l-NG-nitro-arginine autoradiography

1996 • 63 citations

L-NNA-sensitive regional cerebral blood flow augmentation during hypercapnia in type III NOS mutant mice

1996 • 50 citations

Effects in cats of inhibition of nitric oxide synthesis on cerebral vasodilation and endothelium-derived relaxing factor from acetylcholine.

1992 • 47 citations

Regional study of the co-localization of neuronal nitric oxide synthase with muscarinic receptors in the rat cerebral cortex

1995 • 40 citations

Nitric oxide and nitrosothiols in cerebrovascular and neuronal regulation.

1993 • 27 citations

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