7-Nitroindazole Inhibits Brain Nitric Oxide Synthase and Cerebral Vasodilatation in Response to N -Methyl- <scp>d</scp> -aspartate

Nitric oxide synthases in mammals

1994 • 2,762 citations

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1988 • 2,572 citations

Targeted disruption of the neuronal nitric oxide synthase gene

1993 • 1,300 citations

Mapping of neural nitric oxide synthase in the rat suggests frequent co-localization with NADPH diaphorase but not with soluble guanylyl cyclase, and novel paraneural functions for nitrinergic signal transduction.

1992 • 622 citations

Nitric oxide and the cerebral circulation.

1994 • 540 citations

Regulation of the cerebral microcirculation during neural activity: is nitric oxide the missing link?

1993 • 474 citations

Characterization of the novel nitric oxide synthase inhibitor 7‐nitro indazole and related indazoles: antinociceptive and cardiovascular effects

1993 • 470 citations

7‐Nitro indazole, an inhibitor of nitric oxide synthase, exhibits anti‐nociceptive activity in the mouse without increasing blood pressure

1993 • 426 citations

Inhibition of rat cerebellar nitric oxide synthase by 7‐nitro indazole and related substituted indazoles

1993 • 371 citations

Nitric oxide mediates vasodilatation in response to activation of N-methyl-D-aspartate receptors in brain.

1993 • 339 citations

The NOS Inhibitor, 7-Nitroindazole, Decreases Focal Infarct Volume but Not the Response to Topical Acetylcholine in Pial Vessels

1994 • 298 citations

Glutamate Receptor Agonists Stimulate Nitric Oxide Synthase in Primary Cultures of Cerebellar Granule Cells

1992 • 234 citations

Excitatory Amino Acid Receptors Coupled to the Nitric Oxide/Cyclic GMP Pathway in Rat Cerebellum During Development

1991 • 224 citations

The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain.

1994 • 218 citations

Response of cerebral blood vessels to an endogenous inhibitor of nitric oxide synthase

1995 • 160 citations

Time course of inhibition of brain nitric oxide synthase by 7-nitro indazole

1994 • 155 citations

Importance of nitric oxide for local increases of blood flow in rat cerebellar cortex during electrical stimulation.

1994 • 134 citations

Glutamate-Induced Cerebral Vasodilation Is Mediated by Nitric Oxide Through N -Methyl- <scp>d</scp> -Aspartate Receptors

1995 • 130 citations

Different receptors mediate stimulation of nitric oxide-dependent cyclic GMP formation in neurons and astrocytes in culture

1992 • 94 citations

Responses of cerebral arteries after ischemia and reperfusion in cats

1988 • 89 citations

The Inhibition of the Constitutive and Inducible Nitric-Oxide Synthase Isoforms by Indazole Agents

1994 • 88 citations

Dilator effects of amino acid neurotransmitters on piglet pial arterioles

1989 • 88 citations

Nitric oxide contributes to functional hyperemia in cerebellar cortex

1995 • 65 citations

Nitric oxide contributes to dilatation of cerebral arterioles during seizures

1993 • 52 citations

Nitric oxide mediates the increase in local cerebral blood flow during focal seizures.

1995 • 48 citations

Responses of cerebral arterioles to kainate.

1994 • 42 citations

Brain nitric oxide synthase activity in normal, hypertensive, and stroke-prone rats.

1994 • 32 citations

Dilatation of cerebral arterioles in response to N-methyl-d-aspartate: role of CGRP and acetylcholine

1994 • 27 citations

Altered cerebrovascular responsiveness to N-methyl-D-aspartate after asphyxia in piglets

1993 • 26 citations

The influence of opioids on local cerebral glucose utilization in the newborn pig

1992 • 21 citations

Glutamate Receptor-Induced Cyclic GMP Formation in Primary Cultures of Mesencephalic Neurons

1993 • 11 citations