High resolution studies of the Xenopus laevis ribosomal gene promoter in vivo and in vitro.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

A High-Efficiency HeLa Cell Nuclear Transcription Extract

1988 • 612 citations

Sequence-Specific Antirepression of Histone H1-Mediated Inhibition of Basal RNA Polymerase II Transcription

1991 • 378 citations

Functional Cooperativity Between Transcription Factors UBF1 and SL1 Mediates Human Ribosomal RNA Synthesis

1988 • 361 citations

A nuclear extract of xenopus laevis oocytes that accurately transcribes 5S RNA genes

1978 • 323 citations

Local mutagenesis: a method for generating viral mutants with base substitutions in preselected regions of the viral genome.

1978 • 282 citations

A transcriptional function for the repetitive ribosomal spacer in Xenopus laevis

1983 • 274 citations

Ribosomal RNA transcription in vitro is species specific

1982 • 257 citations

Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomes

1991 • 242 citations

Fractiontion and reconstitution of factors required for accurate transcription of mammalian ribosomal RNA genes: identification of a species-depandent initiation factor

1982 • 197 citations

Purification and characterization of a transcription factor that confers promoter specificity to human RNA polymerase I.

1985 • 184 citations

Assembly of alternative multiprotein complexes directs rRNA promoter selectivity.

1990 • 165 citations

An upstream transcription factor, USF (MLTF), facilitates the formation of preinitiation complexes during in vitro chromatin assembly.

1990 • 162 citations

Molecular mechanisms governing species-specific transcription of ribosomal RNA

1989 • 143 citations

Nucleotide sequence requirements for specific initiation of transcription by RNA polymerase I.

1982 • 140 citations

The Xenopus ribosomal gene enhancers bind an essential polymerase I transcription factor, xUBF.

1989 • 130 citations

Promoter occlusion during ribosomal RNA transcription

1988 • 123 citations

Two distinct promoter elements in the human rRNA gene identified by linker scanning mutagenesis.

1986 • 122 citations

Regulation of human ribosomal RNA transcription.

1983 • 117 citations

Characterization of factors that direct transcription of rat ribosomal DNA.

1990 • 106 citations

Nested control regions promote Xenopus ribosomal RNA synthesis by RNA polymerase I

1983 • 99 citations

Determination of the promoter region of mouse ribosomal RNA gene by an in vitro transcription system.

1984 • 94 citations

Transcription of cloned Xenopus laevis ribosomal DNA microinjected into Xenopus oocytes, and the identification of an RNA polymerase I promoter

1982 • 91 citations

Factors and nucleotide sequences that direct ribosomal DNA transcription and their relationship to the stable transcription complex.

1986 • 87 citations

The promoter-proximal rDNA terminator augments initiation by preventing disruption of the stable transcription complex caused by polymerase read-in.

1989 • 86 citations

A complex control region of the mouse rRNA gene directs accurate initiation by RNA polymerase I.

1985 • 83 citations

Linker scanning of the yeast RNA polymerase I promoter

1989 • 78 citations

Analysis of clustered point mutations in the human ribosomal RNA gene promoter by transient expression in vivo.

1988 • 67 citations

Localization of DNA sequences promoting RNA polymerase I activity in Drosophila.

1983 • 64 citations

rUBF, an RNA polymerase I transcription factor from rats, produces DNase I footprints identical to those produced by xUBF, its homolog from frogs.

1990 • 63 citations

An RNA polymerase I termination site can stimulate the adjacent ribosomal gene promoter by two distinct mechanisms in Xenopus laevis.

1990 • 61 citations

Isolation and functional characterization of TIF-IB, a factor that confers promoter specificity to mouse RNA polymerase I

1990 • 61 citations

Half helical turn spacing changes convert a frog into a mouse rDNA promoter: a distant upstream domain determines the helix face of the initiation site.

1990 • 60 citations

The ribosomal spacer inXenopus laevisis transcribed as part of the primary ribosomal RNA

1986 • 55 citations

A component of Drosophila RNA polymerase I promoter lies within the rRNA transcription unit

1983 • 52 citations

The enhancement of ribosomal transcription by the recycling of RNA polymerase I

1987 • 52 citations

The ribosomal RNA promoter ofAcanthamoeba castellaniidetermined by transcription in a cellfree system

1985 • 48 citations

Two distant and precisely positioned domains promote transcription of Xenopus laevis rRNA genes: analysis with linker-scanning mutants.

1986 • 47 citations

Linker scanner mutagenesis of theXenopus laevisribosomal gene promoter

1987 • 43 citations

A transcription factor, TFIS, interacts with both the promoter and enhancer of the Xenopus rRNA genes.

1989 • 42 citations

Upstream domains of the Xenopus laevis rDNA promoter are revealed in microinjected oocytes.

1986 • 33 citations

Effects of single-base substitutions within the Acanthamoeba castellanii rRNA promoter on transcription and on binding of transcription initiation factor and RNA polymerase I.

1988 • 30 citations

Regions upstream from the core promoter of the rat ribosomal gene are required for the formation of a stable transcription initiation complex by RNA polymerase I in vitro

1987 • 29 citations

Deletion mapping of the yeast pol I promoter

1985 • 28 citations

Sequence-specific binding of a transcription factor TFID to the promoter region of mouse ribosomal RNA gene.

1990 • 25 citations

The mouse ribosomal DNA promoter has more stringent requirements in vivo than in vitro.

1990 • 20 citations

The Xenopus laevis ribosomal gene terminator contains sequences that both enhance and repress ribosomal transcription.

1989 • 15 citations

Point mutation analysis of theXenopus laevisRNA polymerase I core promoter

1990 • 11 citations

The Xenopus laevis ribosomal gene promoter contains a binding site for Nuclear Factor-1

1988 • 7 citations