Physiological Changes During Brain Activation

Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation.

1992 • 4,175 citations

Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging.

1992 • 3,618 citations

Tomographic measurement of local cerebral glucose metabolic rate in humans with (F‐18)2‐fluoro‐2‐deoxy‐D‐glucose: Validation of method

1979 • 2,396 citations

Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects.

1986 • 2,017 citations

Time course EPI of human brain function during task activation

1992 • 1,893 citations

Nonoxidative Glucose Consumption During Focal Physiologic Neural Activity

1988 • 1,775 citations

Dynamics of blood flow and oxygenation changes during brain activation: The balloon model

1998 • 1,660 citations

Interactions Between Electrical Activity and Cortical Microcirculation Revealed by Imaging Spectroscopy: Implications for Functional Brain Mapping

1996 • 1,107 citations

Near infrared spectroscopy (NIRS): A new tool to study hemodynamic changes during activation of brain function in human adults

1993 • 1,094 citations

Calibrated functional MRI: Mapping the dynamics of oxidative metabolism

1998 • 1,025 citations

Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity

1998 • 863 citations

A Model for the Coupling between Cerebral Blood Flow and Oxygen Metabolism during Neural Stimulation

1997 • 784 citations

Activity‐dependent Energy Metabolism in Rat Posterior Pituitary Primarily Reflects Sodium Pump Activity

1980 • 581 citations

Review: Does Measurement of Regional Cerebral Blood Flow Reflect Synaptic Activity?—Implications for PET and fMRI

1995 • 520 citations

Relationships among local functional activity, energy metabolism, and blood flow in the central nervous system.

1981 • 486 citations

Metabolic Mapping of Functional Activity in the Hypothalamo-Neurohypophysial System of the Rat

1979 • 464 citations

Human Visual Cortical Function during Photic Stimulation Monitoring by Means of near-Infrared Spectroscopy

1993 • 430 citations

BOLD Based Functional MRI at 4 Tesla Includes a Capillary Bed Contribution: Echo‐Planar Imaging Correlates with Previous Optical Imaging Using Intrinsic Signals

1995 • 428 citations

Dynamic MR imaging of human brain oxygenation during rest and photic stimulation

1992 • 388 citations

Differential effects of electrical stimulation of sciatic nerve on metabolic activity in spinal cord and dorsal root ganglion in the rat.

1985 • 341 citations

Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal brain activation in man

1996 • 320 citations

Quantitative capillary topography and blood flow in the cerebral cortex of cats: an in vivo microscopic study

1981 • 313 citations

Metabolic mapping of the primary visual system of the monkey by means of the autoradiographic [14C]deoxyglucose technique.

1976 • 306 citations

Capillary perfusion of the rat brain cortex. An in vivo confocal microscopy study.

1994 • 292 citations

Persistent Resetting of the Cerebral Oxygen/Glucose Uptake Ratio by Brain Activation: Evidence Obtained with the Kety—Schmidt Technique

1995 • 255 citations

Cellular Bases of Brain Energy Metabolism and Their Relevance to Functional Brain Imaging: Evidence for a Prominent Role of Astrocytes

1996 • 233 citations

Cerebral oxygenation changes in response to motor stimulation

1996 • 230 citations

Stimulation‐induced [¹⁴C]2‐deoxyglucose labeling of synaptic activity in the central auditory system

1986 • 227 citations

Functional Activation of Cerebral Blood Flow and Metabolism before and after Global Ischemia of Rat Brain

1988 • 221 citations

Interdependency of local capillary density, blood flow, and metabolism in rat brains

1986 • 210 citations

Vibratory stimulation increases and decreases the regional cerebral blood flow and oxidative metabolism: a positron emission tomography (PET) study

1992 • 207 citations

Coupling of cerebral blood flow to neuronal activation: role of adenosine and nitric oxide

1994 • 188 citations

Increased tricarboxylic acid cycle flux in rat brain during forepaw stimulation detected with 1H[13C]NMR.

1996 • 188 citations

Age Dependency of Changes in Cerebral Hemoglobin Oxygenation during Brain Activation: A Near-Infrared Spectroscopy Study

1995 • 162 citations

Regional control of cerebral vascular reactivity and oxygen supply in man

1966 • 145 citations

Brain Metabolism during Short-Term Starvation in Humans

1994 • 135 citations

Noninvasive somatosensory homunculus mapping in humans by using a large-array biomagnetometer.

1993 • 133 citations

Noninvasive measurement of blood flow, oxygen consumption, and glucose utilization in the same brain regions in man by positron emission tomography: concise communication.

1982 • 129 citations

Determination of rat cerebral cortical blood volume changes by capillary mean transit time analysis during hypoxia, hypercapnia and hyperventilation

1988 • 127 citations

The mechanisms controlling physiologically stimulated changes in rat brain glucose and lactate: a microdialysis study.

1996 • 126 citations

Regional changes in cerebral haemodynamics as a result of a visual stimulus measured by near infrared spectroscopy

1995 • 125 citations

Oxidative Glucose Metabolism in Rat Brain during Single Forepaw Stimulation: A Spatially Localized ¹H[¹³C] Nuclear Magnetic Resonance Study

1997 • 125 citations

Congruence of total and perfused capillary network in rat brains.

1990 • 121 citations

Extraretinal modulation of cerebral blood flow in the human visual cortex: implications for saccadic suppression

1995 • 112 citations

Lack of Capillary Recruitment in the Brains of Awake Rats during Hypercapnia

1989 • 112 citations

Hypoxia Increases Velocity of Blood Flow through Parenchymal Microvascular Systems in Rat Brain

1993 • 109 citations

Changes in Brain Capillary Diameter during Hypocapnia and Hypercapnia

1993 • 91 citations

Nuclear magnetic resonance imaging and spectroscopy of human brain function.

1993 • 87 citations

Temporal characteristics of oxygenation‐sensitive MRI responses to visual activation in humans

1998 • 86 citations

Eye movement-related inhibition of primate visual neurons

1975 • 81 citations

Simultaneous measurement of blood flow and glucose metabolism by autoradiographic techniques.

1981 • 74 citations

Global increase in cerebral metabolism and blood flow produced by focal electrical stimulation of dorsal medullary reticular formation in rat

1983 • 73 citations

Activation-Induced Resetting of Cerebral Oxygen and Glucose Uptake in the Rat

1998 • 73 citations

Tracer Oxygen Distribution Is Barrier-Limited in the Cerebral Microcirculation

1995 • 70 citations

Cerebral haemoglobin oxygenation during sustained visual stimulation – a near–infrared spectroscopy study

1997 • 70 citations

Changes of Blood Flow and Oxygen Consumption in Visual Cortex of Living Humans

1997 • 61 citations

Local cerebral glucose utilization and blood flow during metabolic acidosis

1981 • 60 citations

Topography of Capillary Density, Glucose Metabolism, and Microvascular Function within the Rat Inferior Colliculus

1987 • 57 citations

Measurement of cerebral capillary perfusion with a fluorescent label

1988 • 57 citations

Cerebral metabolic mapping at the cellular level with dry-mount autoradiography of [3H]2-deoxyglucose

1987 • 53 citations

Nicotine Raises the Influx of Permeable Solutes across the Rat Blood—Brain Barrier with Little or No Capillary Recruitment

1995 • 52 citations

Scopolamine abolishes cerebral blood flow response to somatosensory stimulation in anesthetized cats: PET study

1994 • 52 citations

Heterogeneity and Stability of Local PO2 Distribution within the Brain Tissue

1994 • 51 citations

Local oxygen tension and spike activity of the cerebral grey matter of the rat and its response to short intervals of O2 deficiency or CO2 excess

1977 • 46 citations

Cerebral blood oxygenation changes induced by visual stimulation in humans

1996 • 44 citations

Patterns of Capillary Plasma Perfusion in Brains of Conscious Rats During Normocapnia and Hypercapnia

1995 • 40 citations

Chapter 30: Density of perfused capillaries in living human brain during functional activation

1992 • 39 citations

Brain activity patterns: Assessment by high resolution autoradiographic imaging of radiolabeled 2-deoxyglucose and glucose uptake

1991 • 39 citations

The effects of intravenous norepinephrine on the local coupling between glucose utilization and blood flow in the rat brain

1983 • 37 citations

Stimulus dependence of oxygenation-sensitive MRI responses to sustained visual activation

1998 • 34 citations

Blood Oxygenation Level Dependent Signal Time Courses During Prolonged Visual Stimulation

1998 • 32 citations

Tissue Oxygen Tension in the Cerebral Cortex of the Rabbit

1989 • 27 citations

Visual Activation in α‐Chloralose‐anaesthetized Cats Does Not Cause Lactate Accumulation in the Visual Cortex as Detected by [¹HINMR Difference Spectroscopy

1997 • 19 citations

The determination of the local cerebral glucose utilization with the 2-deoxyglucose method

1988 • 14 citations

Millisecond sequencing of neural activation in simple tasks determined by the BOLD fMRI neurovascular response

1998 • 6 citations

Imbalance of regional cerebral blood flow and oxygen consumption: Effect of vascular alpha adrenoceptor blockade

1993 • 4 citations

Posters: Vision

1997 • 2 citations