Tomographic measurement of local cerebral glucose metabolic rate in humans with (F‐18)2‐fluoro‐2‐deoxy‐D‐glucose: Validation of method

THE [¹⁴C]DEOXYGLUCOSE METHOD FOR THE MEASUREMENT OF LOCAL CEREBRAL GLUCOSE UTILIZATION: THEORY, PROCEDURE, AND NORMAL VALUES IN THE CONSCIOUS AND ANESTHETIZED ALBINO RAT¹

1977 • 5,986 citations

The [18F]fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man.

1979 • 1,184 citations

Quantitation in Positron Emission Computed Tomography

1979 • 1,138 citations

The Effects of Changes in Pa <scp>CO</scp> ₂ Cerebral Blood Volume, Blood Flow, and Vascular Mean Transit Time

1974 • 1,015 citations

Metabolic trapping as a principle of oradiopharmaceutical design: some factors resposible for the biodistribution of [18F] 2-deoxy-2-fluoro-D-glucose.

1978 • 557 citations

Quantitation in Positron Emission Computed Tomography

1979 • 445 citations

THE QUANTITATIVELY MINOR ROLE OF CARBOHYDRATE IN OXIDATIVE METABOLISM BY SKELETAL MUSCLE IN INTACT MAN IN THE BASAL STATE. MEASUREMENTS OF OXYGEN AND GLUCOSE UPTAKE AND CARBON DIOXIDE AND LACTATE PRODUCTION IN THE FOREARM 12

1956 • 393 citations

Effects of hypoxia and normocarbia on cerebral blood flow and metabolism in conscious man.

1967 • 372 citations

THE CEREBRAL BLOOD FLOW IN MALE SUBJECTS AS MEASURED BY THE NITROUS OXIDE TECHNIQUE. NORMAL VALUES FOR BLOOD FLOW, OXYGEN UTILIZATION, GLUCOSE UTILIZATION, AND PERIPHERAL RESISTANCE, WITH OBSERVATIONS ON THE EFFECT OF TILTING AND ANXIETY 1

1949 • 367 citations

Isolation of metabolically active capillaries from rat brain^1,2

1975 • 316 citations

ECAT: a new computerized tomographic imaging system for position-emitting radiopharmaceuticals

1977 • 249 citations

The Effects of Ketamine on Cerebral Circulation and Metabolism in Man

1972 • 248 citations

Local cerebral glucose utilization in the normal conscious macaque monkey

1978 • 246 citations

Investigation of [18F]2-fluoro-2-deoxyglucose for the measure of myocardial glucose metabolism.

1978 • 221 citations

Radiopharmaceuticals XXVII. 18F-labeled 2-deoxy-2-fluoro-d-glucose as a radiopharmaceutical for measuring regional myocardial glucose metabolism in vivo: tissue distribution and imaging studies in animals.

1977 • 205 citations

Emission computed tomography

1977 • 178 citations

Kinetics of unidirectional glucose transport into the isolated dog brain

1973 • 172 citations

HETEROGENEITY OF FOREARM METABOLISM WITH SPECIAL REFERENCE TO FREE FATTY ACIDS*

1962 • 162 citations

EFFECT OF INSULIN ON CARBOHYDRATE METABOLISM AND ON POTASSIUM IN THE FOREARM OF MAN*

1962 • 153 citations

The use of deoxyfluoro-<scp>d</scp>-glucopyranoses and related compounds in a study of yeast hexokinase specificity

1972 • 148 citations

Der Kohlenhydratstoffwechsel des menschlichen Gehirns

1963 • 134 citations

Local cerebral blood volume response to carbon dioxide in man.

1978 • 129 citations

Medical Radionuclide Imaging

1978 • 127 citations

Blood-brain transfer of glucose and other molecules measured by rapid indicator dilution

1971 • 124 citations

Sugar transport across the blood-brain barrier

1970 • 124 citations

In vivo measurement of brain glucose transport and metabolism employing glucose- -11C

1975 • 116 citations

Measurement of local cerebral glucose metabolism in man with 18F-2-fluoro-2-deoxy-d-glucose.

1977 • 115 citations

Loss of radioactive 2-deoxy-d-glucose-6-phosphate from brains of conscious rats: Implications for quantitative autoradiographic determination of regional glucose utilization

1978 • 100 citations

Local cerebral blood volume in head-injured patients

1980 • 96 citations

Local cerebral blood volume determined by three-dimensional reconstruction of radionuclide scan data.

1975 • 96 citations

Effect of arterial CO 2 tension on cerebral blood flow, mean transit time, and vascular volume.

1971 • 85 citations

Measurement of Regional Substrate Utilization Rates by Emission Tomography

1978 • 69 citations

A METHOD OF OBTAINING FROM VEINS BLOOD SIMILAR TO ARTERIAL BLOOD IN GASEOUS CONTENT

1925 • 68 citations

Regional Cerebral Blood Volume in Humans

1973 • 67 citations

Correlation between PaCO2 and regional cerebral blood volume by x-ray fluorescence.

1973 • 62 citations

Mediated transport of glucose between blood and brain in the cat

1971 • 57 citations

In vivo regional cerebral blood volume by x-ray fluorescence: validation of method.

1973 • 53 citations

Studies of the Cerebral Circulation and Metabolism in Congestive Heart Failure

1953 • 48 citations

Cytochemical localization of glucose-6-phosphatase activity in the central nervous system of the rat

1976 • 48 citations

Cerebral glucose-6-phosphatase and the movement of 2-deoxy-D-glucose across cell membranes.

1977 • 44 citations

Effect of Insulin on the Synthesis of Glycogen in Cerebral Cortical Slices of Alloxan Diabetic Rats

1968 • 40 citations

Glucose-6-Phosphatase Activity in Various Sheep Tissues.

1960 • 27 citations

UPTAKE OF GLUCOSE ANALOGUES BY RAT BRAIN CORTEX SLICES: MEMBRANE TRANSPORT VERSUS METABOLISM OF 2‐DEOXY‐<scp>d</scp>‐GLUCOSE

1977 • 23 citations

Design and application of the MARK IV scanning system for radionuclide computed tomography of the brain

1976 • 12 citations

RELATIONSHIP OF LOCAL CEREBRAL GLUCOSE UTILIZATION AND RELATIVE PERFUSION IN STROKE AND EPILEPSY

1978 • 7 citations

THE USE OF “ARTERIALIZED” BLOOD FOR THE DETERMINATION OF ARTERIAL O2 AND CO2 TENSIONS

1955 • 6 citations

CHAPTER XXIV NEW METHODS

1977 • 5 citations

VALIDATION OF THE NONINVASIVE TOMOGRAPHIC MEASURE OF REGIONAL CEREBRAL GLUCOSE METABOLISM IN MAN WITH 18F-2-FLUORO-2-DEOXY-GLUCOSE

1978 • 4 citations