Pathophysiology of L-Dopa-Induced Abnormal Involuntary Movements

Brain dopamine and the syndromes of Parkinson and Huntington Clinical, morphological and neurochemical correlations

1973 • 2,615 citations

Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,922 citations

Brain dopamine receptors.

1980 • 1,878 citations

Dopamine (3-hydroxytyramine) and brain function.

1966 • 1,401 citations

Greenfield's neuropathology

1976 • 961 citations

Dendritic release of dopamine in the substantia nigra

1981 • 732 citations

Dopamine Receptor Binding Enhancement Accompanies Lesion-Induced Behavioral Supersensitivity

1977 • 716 citations

Reduction of cortical dopamine, noradrenaline, serotonin and their metabolites in Parkinson's disease

1983 • 712 citations

Gilles de la Tourette Syndrome

2021 • 545 citations

Receptor basis for dopaminergic supersensitivity in Parkinson's disease

1978 • 447 citations

Is the mesocortical dopaminergic system involved in Parkinson disease?

1980 • 412 citations

Hyperactivity of Remaining Dopaminergic Neurones after Partial Destruction of the Nigro-striatal Dopaminergic System in the Rat

1973 • 363 citations

Fluctuations of disability in Parkinson's disease – clinical aspects

1981 • 281 citations

Neurotransmitter receptor alterations in Parkinson's disease

1977 • 251 citations

L-dopa therapy of Parkinson's disease: plasma L-dopa concentration, therapeutic response, and side effects.

1971 • 232 citations

L-Dopa and Parkinsonism

1970 • 221 citations

[3H]spiperone binding, dopamine and HVA concentrations in Parkinson's disease and supranuclear palsy

1984 • 215 citations

STRIATAL AMINES, EXPERIMENTAL TREMOR AND THE EFFECT OF HARMALINE IN THE MONKEY

1966 • 205 citations

Demonstration of nigrotectal and nigroreticular projections in the cat by axonal transport of proteins

1976 • 204 citations

Modification of Chronic Manganese Poisoning

1970 • 195 citations

Behavioral correlations of dopamine receptor activation

1983 • 188 citations

L-Dopa and Parkinsonism.

1971 • 157 citations

Growth of Pulmonary Alveolar Macrophages in vitro

1973 • 155 citations

Decrease of substance P-like immunoreactivity in the substantia nigra and pallidum of parkinsonian brains

1983 • 148 citations

3-0-Methyldopa uptake and inhibition of L-dopa at the blood-brain barrier

1975 • 140 citations

Patterns of dystonia ("I-D-I" and "D-I-D-") in response to l-dopa therapy for Parkinson's disease.

1977 • 138 citations

Evidence that apomorphine and pergolide induce rotation in rats by different actions on D1 and D2 receptor sites

1984 • 124 citations

Analysis of L-dopa induced dyskinesias in 51 patients with Parkinsonism

1971 • 104 citations

Onset and End-of-Dose Levodopa-Induced Dyskinesias

1978 • 90 citations

MONOAMINES NOYAUX GRIS CENTRAUX ET SYNDROME DE PARKINSON

1975 • 87 citations

Parkinson's disease affects differently Met5- and Leu5-enkephalin in the human brain

1983 • 87 citations

Biochemistry of the hypothalamus in Parkinson's disease

1984 • 83 citations

Catecholamines. Part C: Neuropharmacology and central nervous system—Therapeutic aspects

1985 • 75 citations

Metoclopramide and pimozide in Parkinson's disease and levodopa-induced dyskinesias.

1975 • 71 citations

Micro topography of Tyrosine Hydroxylase, Glutamic Acid Decarboxylase, and Choline Acetyltransferase in the Substantia Nigra and Ventral Tegmental Area of Control and Parkinsonian Brains

1981 • 68 citations

Alterations in [3H]spiperone binding in human caudate nucleus, substantia nigra and frontal cortex in the Shy-Drager syndrome and Parkinson's disease

1979 • 66 citations

The Clinical Picture and Plasma Levodopa Metabolite Profile of Parkinsonian Nonresponders

1977 • 64 citations

Attempted use of haloperidol in the treatment of L-dopa induced dyskinesias

1974 • 62 citations

Spontaneous activity of the putamen after chronic interruption of the dopaminergic pathway: effect of L-dopa.

1970 • 55 citations

Adverse clinical side effects of levodopa therapy.

1971 • 52 citations

Effect of chronic amphetamine exposure on stereotyped behavior: implications for pathogenesis of l-dopa-induced dyskinesias.

1975 • 51 citations

Metabolic Studies and Clinical Observations During L-Dopa Treatment of Parkinson's Disease

1970 • 47 citations

Dopamine-sensitive adenylate cyclase activity in the striatum in Parkinson's disease

1979 • 47 citations

L-dopa-induced accumulation of 3-O-methyldopa in brain and heart

1970 • 45 citations

Dopamine-stimulated adenylate cyclase activity in the human brain: Changes in Parkinsonism

1978 • 29 citations

Parkinson-Specific Motor and Mental Disorders: Role of the Pallidum : Pathophysiological, Biochemical, and Therapeutic Aspects

1983 • 29 citations

Hyperkinesia and changes in behavior produced in normal monkeys by L‐dopa

1972 • 28 citations

["Beginning and end of dose" dyskinesias caused by L-DOPA].

1977 • 21 citations

Plasma 3-0-methyldopa in L-dopa therapy of Parkinson's disease.

1972 • 21 citations

Reversal of the reserpine syndrome with L‐dopa metabolites in reserpinized rats

1971 • 16 citations

Dopamine-sensitive adenylate cyclase activity in the caudate nucleus and adrenal medulla in Parkinson's disease and in liver cirrhosis.

1978 • 16 citations

PLASMA O-METHYLDOPA IN LEVODOPA-INDUCED DYSKINESIAS A Bioclinical Investigation

2009 • 16 citations

Parkinson's disease: low density and presynaptic location of D3 dopamine receptors

1981 • 16 citations

Thyrotropin releasing hormone content is unchanged in brains of patients with Parkinson disease

1983 • 13 citations

[Abnormal movements caused by L-DOPA in patients with Parkinson's disease: correlation with the plasma concentrations of DOPA and O-methyl-DOPA].

1977 • 12 citations

DYSKINESIAS DURING LEVODOPA THERAPY

1975 • 10 citations

Long-term effects of nigro-striatal denervation on striatal [3H]haloperidol binding

1981 • 9 citations

Neurological and psychiatric side-effects of L-DOPA

1976 • 9 citations

[Abnormal movements observed during treatment of Parkinson's disease with L-dopa].

1970 • 3 citations