Effects of ACE inhibition on cardiomyocyte apoptosis in dogs with heart failure

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Effect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure

1991 • 8,296 citations

Effect of Enalapril on Mortality and the Development of Heart Failure in Asymptomatic Patients with Reduced Left Ventricular Ejection Fractions

1992 • 3,708 citations

Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system.

1991 • 2,017 citations

Apoptosis in the Failing Human Heart

1997 • 1,690 citations

Shrinkage necrosis: A distinct mode of cellular death

1971 • 1,448 citations

Apoptosis in Myocytes in End-Stage Heart Failure

1996 • 1,446 citations

Reperfusion injury induces apoptosis in rabbit cardiomyocytes.

1994 • 1,431 citations

Effect of Captopril on Progressive Ventricular Dilatation after Anterior Myocardial Infarction

1988 • 1,119 citations

Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis.

1991 • 861 citations

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis.

1994 • 820 citations

Toward an understanding of the molecular mechanisms of physiological cell death.

1993 • 623 citations

Usefulness and limitations of radiographic methods for determining left ventricular volume

1966 • 622 citations

Effects of the angiotensin converting enzyme inhibitor enalapril on the long-term progression of left ventricular dysfunction in patients with heart failure. SOLVD Investigators.

1992 • 608 citations

In situ end‐labelling detects DNA strand breaks in apoptosis and other physiological and pathological states

1993 • 584 citations

Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes.

1994 • 560 citations

Apoptosis-the molecular basis of cell death

1992 • 517 citations

Internucleosomal DNA Cleavage Should not be the Sole Criterion for Identifying Apoptosis

1992 • 462 citations

Angiotensin II and Other Hypertrophic Stimuli Mediated by G Protein–Coupled Receptors Activate Tyrosine Kinase, Mitogen-Activated Protein Kinase, and 90-kD S6 Kinase in Cardiac Myocytes

1995 • 412 citations

The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max.

1993 • 392 citations

Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure.

1996 • 335 citations

Increased cardiomyocyte apoptosis during the transition to heart failure in the spontaneously hypertensive rat

1997 • 304 citations

A canine model of chronic heart failure produced by multiple sequential coronary microembolizations

1991 • 291 citations

Left ventricular remodeling in the year after first anterior myocardial infarction: A quantitative analysis of contractile segment lengths and ventricular shape

1992 • 274 citations

Reactive and reparative myocardial fibrosis in arterial hypertension in the rat

1992 • 268 citations

Apoptosis and Its Role in Human Disease

1994 • 232 citations

Effects of long-term monotherapy with enalapril, metoprolol, and digoxin on the progression of left ventricular dysfunction and dilation in dogs with reduced ejection fraction.

1994 • 207 citations

Induction and nuclear accumulation of fos and jun proto-oncogenes in hypoxic cardiac myocytes

1993 • 206 citations

Hypoxia/Reoxygenation Stimulates Jun Kinase Activity Through Redox Signaling in Cardiac Myocytes

1997 • 179 citations

Progression of heart failure: A role for interstitial fibrosis

1995 • 163 citations

Hypoxia and Hypoxia/Reoxygenation Activate Raf-1, Mitogen-Activated Protein Kinase Kinase, Mitogen-Activated Protein Kinases, and S6 Kinase in Cultured Rat Cardiac Myocytes

1996 • 120 citations

Abnormalities of cardiocytes in regions bordering fibrous scars of dogs with heart failure

1997 • 43 citations

Apoptosis and Cell Proliferation Are Terms of the Growth Equation

1991 • 25 citations

Ventricular remodeling: insights from pharmacologic interventions with angiotensin-converting enzyme inhibitors

1995 • 23 citations

Ventricular remodeling: insights from pharmacologic interventions with angiotensin-converting enzyme inhibitors

1995 • 22 citations

Enalapril but not metoprolol improves capillary density and oxygen diffusion distance in left ventricular myocardium of dogs with moderate heart failure

1996 • 8 citations

-Receptors and -Blockers in Congestive Heart Failure

1994 • 1 citations