Functional differences between the two splice variants of the nucleolar transcription factor UBF: the second HMG box determines specificity of DNA binding and transcriptional activity.

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

1992 • 684 citations

Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins

1990 • 656 citations

SRY, like HMG1, recognizes sharp angles in DNA.

1992 • 439 citations

Structure of the HMG box motif in the B-domain of HMG1.

1993 • 403 citations

Sequence-Specific Antirepression of Histone H1-Mediated Inhibition of Basal RNA Polymerase II Transcription

1991 • 378 citations

Functional Cooperativity Between Transcription Factors UBF1 and SL1 Mediates Human Ribosomal RNA Synthesis

1988 • 361 citations

The DNA binding site of HMG1 protein is composed of two similar segments (HMG boxes), both of which have counterparts in other eukaryotic regulatory proteins.

1992 • 259 citations

Sequence-specific interaction of the HMG box proteins TCF-1 and SRY occurs within the minor groove of a Watson-Crick double helix.

1992 • 218 citations

The nucleolar transcription factor mUBF is phosphorylated by casein kinase II in the C-terminal hyperacidic tail which is essential for transactivation.

1992 • 195 citations

Assembly of alternative multiprotein complexes directs rRNA promoter selectivity.

1990 • 165 citations

HMG has DNA wrapped up

1992 • 161 citations

Multiple domains of the RNA polymerase I activator hUBF interact with the TATA-binding protein complex hSL1 to mediate transcription.

1992 • 159 citations

Human autoantibody to RNA polymerase I transcription factor hUBF. Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factor.

1991 • 157 citations

Molecular mechanisms governing species-specific transcription of ribosomal RNA

1989 • 143 citations

A growth-dependent transcription initiation factor (TIF-IA) interacting with RNA polymerase I regulates mouse ribosomal RNA synthesis.

1990 • 130 citations

The Xenopus ribosomal gene enhancers bind an essential polymerase I transcription factor, xUBF.

1989 • 130 citations

Transcription complex formation at the mouse rDNA promoter involves the stepwise association of four transcription factors and RNA polymerase I.

1991 • 125 citations

Identification of two forms of the RNA polymerase I transcription factor UBF.

1991 • 120 citations

Dual role of the nucleolar transcription factor UBF: trans-activator and antirepressor.

1992 • 110 citations

A purified transcription factor (TIF-IB) binds to essential sequences of the mouse rDNA promoter.

1986 • 108 citations

Characterization of factors that direct transcription of rat ribosomal DNA.

1990 • 106 citations

Growth-dependent regulation of rRNA synthesis is mediated by a transcription initiation factor (TTF-IA)

1985 • 105 citations

Interaction of a protein from rat liver nuclei with cruciform DNA.

1988 • 105 citations

Mechanism of transcriptional antirepression by GAL4-VP16.

1992 • 97 citations

A TBP-containing multiprotein complex (TIF-IB) mediates transcription specificity of murine RNA polymerase I

1993 • 95 citations

Enhancers for RNA polymerase I in mouse ribosomal DNA.

1990 • 93 citations

Mouse rRNA gene transcription factor mUBF requires both HMG-box1 and an acidic tail for nucleolar accumulation: molecular analysis of the nucleolar targeting mechanism.

1992 • 89 citations

xUBF contains a novel dimerization domain essential for RNA polymerase I transcription.

1991 • 83 citations

Function of the growth-regulated transcription initiation factor TIF-IA in initiation complex formation at the murine ribosomal gene promoter.

1993 • 81 citations

Analysis of the phosphorylation, DNA-binding and dimerization properties of the RNA polymerase I transcription factors UBF1 and UBF2

1992 • 81 citations

The nucleolar transcription activator UBF relieves Ku antigen-mediated repression of mouse ribosomal gene transcription

1993 • 80 citations

A novel promoter in the mouse rDNA spacer is active in vivo and in vitro.

1987 • 78 citations

Cloning and structural analysis of cDNA and the gene for mouse transcription factor UBF

1991 • 76 citations

In vitro mutagenesis and transcriptional analysis of a mouse ribosomal promoter element.

1984 • 73 citations

A 140-base-pair repetitive sequence element in the mouse rRNA gene spacer enhances transcription by RNA polymerase I in a cell-free system.

1990 • 61 citations

A strategy for efficientin vitrotranslation of cDNAs using the rabbit β-globin leader sequence

1991 • 61 citations

Isolation and functional characterization of TIF-IB, a factor that confers promoter specificity to mouse RNA polymerase I

1990 • 61 citations

Recognition of the Xenopus ribosomal core promoter by the transcription factor xUBF involves multiple HMG box domains and leads to an xUBF interdomain interaction.

1993 • 57 citations

Characterization of Factors That Direct Transcription of Rat Ribosomal DNA

1990 • 44 citations

An RNA polymerase I promoter located in the CHO and mouse ribosomal DNA spacers: functional analysis and factor and sequence requirements.

1989 • 40 citations

Function of the Growth-Regulated Transcription Initiation Factor TIF-IA in Initiation Complex Formation at the Murine Ribosomal Gene Promoter

1993 • 38 citations

Enhancers for RNA Polymerase I in Mouse Ribosomal DNA

1990 • 38 citations

An RNA Polymerase I Promoter Located in the CHO and Mouse Ribosomal DNA Spacers: Functional Analysis and Factor and Sequence Requirements

1989 • 16 citations