Morphogen gradients

The chemical basis of morphogenesis

1952 • 11,233 citations

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

MECHANISMS OF WNT SIGNALING IN DEVELOPMENT

1998 • 2,028 citations

Embryonic Development and Induction

1939 • 1,175 citations

Transcriptional Activators of TGF-β Responses: Smads

1998 • 1,024 citations

Direct and Long-Range Action of a DPP Morphogen Gradient

1996 • 896 citations

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

1991 • 799 citations

Direct and Long-Range Action of a Wingless Morphogen Gradient

1996 • 736 citations

Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A

1990 • 660 citations

Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing

1996 • 629 citations

Cytonemes

1999 • 602 citations

Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate

1990 • 508 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

Wingless Repression of Drosophila frizzled 2 Expression Shapes the Wingless Morphogen Gradient in the Wing

1998 • 331 citations

Activin signalling and response to a morphogen gradient

1994 • 328 citations

Positional information revisited

1989 • 322 citations

Transducing the Dpp Morphogen Gradient in the Wing of Drosophila

1999 • 280 citations

One hundred years of positional information

1996 • 269 citations

The Drosophila Gene brinker Reveals a Novel Mechanism of Dpp Target Gene Regulation

1999 • 262 citations

brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes

1999 • 232 citations

The gene teashirt is required for the development of Drosophila embryonic trunk segments and encodes a protein with widely spaced zinc finger motifs

1991 • 208 citations

Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginal disc

1998 • 202 citations

The roles of the homeobox genes aristaless and Distal-less in patterning the legs and wings of Drosophila

1998 • 194 citations

Problems and paradigms: Morphogens and pattern formation

1997 • 184 citations

Gradients in the Insect Segment: The Orientation of Hairs in the Milkweed Bug Oncopeltus Fasciatus

1966 • 178 citations

The homeobox gene Distal-less induces ventral appendage development in Drosophila

1997 • 163 citations

Direct and continuous assessment by cells of their position in a morphogen gradient

1995 • 150 citations

The Vestigial gene product provides a molecular context for the interpretation of signals during the development of the wing in Drosophila

1999 • 111 citations

Cells’ Perception of Position in a Concentration Gradient

1998 • 107 citations

Interaction of goosecoid and brachyury in Xenopus mesoderm patterning

1997 • 97 citations

A quantitative analysis of signal transduction from activin receptor to nucleus and its relevance to morphogen gradient interpretation

1999 • 90 citations

Mechanism by which Cells estimate their Location within the Body

1966 • 83 citations

Trunk-specific modulation of Wingless signalling in Drosophila by Teashirt binding to Armadillo

1998 • 75 citations

The C-terminal domain of Armadillo binds to hypophosphorylated Teashirt to modulate Wingless signalling in Drosophila

1999 • 74 citations

Morphogenetic gradients — past and present

1987 • 58 citations

An experimental system for analyzing response to a morphogen gradient.

1996 • 36 citations