A disulfide bond in antithrombin is required for heparin-accelerated thrombin inactivation.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

The Purification and Mechanism of Action of Human Antithrombin-Heparin Cofactor

1973 • 1,363 citations

Glycosaminoglycans and Their Binding to Biological Macromolecules

1978 • 835 citations

Purification of antithrombin III by affinity chromatography

1974 • 426 citations

Structural Aspects of the Fibrinogen to Fibrin Conversion

1973 • 387 citations

Progress in Hemostasis and Thrombosis.

1974 • 349 citations

Heparin cofactor activity measured with an amidolytic method

1975 • 341 citations

[7] Isolation and characterization of connective tissue polysaccharides

1972 • 280 citations

Highly Purified Antithrombin III with Heparin Cofactor Activity Prepared by Disc Electrophoresis

1968 • 274 citations

[14] Thrombin

1976 • 214 citations

Identity of Plasma-activated Factor X Inhibitor with Antithrombin III and Heparin Cofactor

1971 • 195 citations

Inhibition of human factor IXa by human antithrombin

1975 • 179 citations

Characterization of human, bovine, and horse antithrombin III

1976 • 168 citations

The Inhibition of Human Plasmin by Human Antithrombin-Heparin Cofactor

1974 • 163 citations

Nonenzymic reactivation of reduced bovine pancreatic ribonuclease by air oxidation and by glutathione oxidoreduction buffers.

1975 • 159 citations

Comparison of the inhibition of thrombin by three plasma protease inhibitors

1978 • 159 citations

The Binding of Low-Affinity and High-Affinity Heparin to Antithrombin. Fluorescence Studies

1978 • 136 citations

Binding of heparin to human antithrombin III as studied by measurements of tryptophan fluorescence

1977 • 114 citations

The role of heparin in the thrombin-antithrombin III reaction

1976 • 78 citations

A MODIFIED METHOD FOR THE COLORIMETRIC DETERMINATION OF HEPARIN

1967 • 71 citations

New methods for the preparation of biospecific adsorbents and immobilized enzymes utilizing trichloro-s-triazine

1978 • 67 citations

Problems in the assay of thrombin using synthetic peptides as substrates

1977 • 61 citations

Antibody as an immunological probe for studying the refolding of bovine serum albumin. I. The catalysis of reoxidation of reduced bovine serum albumin by glutathione and a disulfide interchange enzyme.

1976 • 61 citations

Purification of thrombin by affinity chromatography on immobilized heparin

1977 • 39 citations

Decreased Heparin Sensitivity of Cyclohexanedione-Modified Thrombin

1978 • 31 citations

Effect of heparin on the extent of inhibition of thrombin by heparin cofactor

1977 • 17 citations

Small-angle X-ray scattering studies on human antithrombin III and its complex with heparin

1977 • 11 citations